Smad2 protects against TGF-beta/Smad3-mediated renal fibrosis. (Q34455322)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20595680%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

title

Smad2 protects against TGF-beta/Smad3-mediated renal fibrosis (English)

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6 February 2020

6

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6 February 2020

Hui Y Lan

9

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6 February 2020

author name string

Xiao Ming Meng

1

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6 February 2020

Xiao Ru Huang

2

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6 February 2020

Arthur C K Chung

3

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6 February 2020

Wei Qin

4

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6 February 2020

Xinli Shao

5

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6 February 2020

Wenjun Ju

7

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6 February 2020

Erwin P Bottinger

8

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6 February 2020

publication date

1 July 2010

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Journal of the American Society of Nephrology

6 February 2020

published in

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6 February 2020

volume

21

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6 February 2020

issue

9

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6 February 2020

page(s)

1477-1487

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Advanced glycation end-products induce tubular CTGF via TGF-beta-independent Smad3 signaling

6 February 2020

cites work

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Angiotensin II induces connective tissue growth factor and collagen I expression via transforming growth factor-beta-dependent and -independent Smad pathways: the role of Smad3

6 July 2018

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Role of SARA (SMAD anchor for receptor activation) in maintenance of epithelial cell phenotype.

6 July 2018

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Latent TGF-beta1 protects against crescentic glomerulonephritis

6 July 2018

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Essential role of Smad3 in angiotensin II-induced vascular fibrosis

6 July 2018

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Renal fibrosis: new insights into the pathogenesis and therapeutics

6 July 2018

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Deletion of Smad2 in mouse liver reveals novel functions in hepatocyte growth and differentiation

6 July 2018

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Smad3 is key to TGF-beta-mediated epithelial-to-mesenchymal transition, fibrosis, tumor suppression and metastasis.

6 July 2018

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The differential role of Smad2 and Smad3 in the regulation of pro-fibrotic TGFbeta1 responses in human proximal-tubule epithelial cells.

6 July 2018

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Signaling mechanism of TGF-beta1 in prevention of renal inflammation: role of Smad7.

6 July 2018

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Transforming growth factor-beta and Smad signalling in kidney diseases.

6 July 2018

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Smad3 as a mediator of the fibrotic response

6 July 2018

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Integration of TGF-beta/Smad and Jagged1/Notch signalling in epithelial-to-mesenchymal transition

6 July 2018

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Targeted disruption of TGF-β1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction

6 July 2018

1 reference

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Smad-dependent and Smad-independent pathways in TGF-beta family signalling

6 July 2018

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Smad3: a key player in pathogenetic mechanisms dependent on TGF-beta

6 July 2018

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Smad3 and PKCdelta mediate TGF-beta1-induced collagen I expression in human mesangial cells

6 July 2018

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TGF-beta signaling in renal disease

6 July 2018

1 reference

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Smad3/AP-1 interactions control transcriptional responses to TGF-beta in a promoter-specific manner

6 July 2018

1 reference

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Identification of novel TGF-beta /Smad gene targets in dermal fibroblasts using a combined cDNA microarray/promoter transactivation approach.

6 July 2018

1 reference

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Mice lacking Smad3 show accelerated wound healing and an impaired local inflammatory response

6 July 2018

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Postgastrulation Smad2-deficient embryos show defects in embryo turning and anterior morphogenesis

6 July 2018

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Targeted disruption of SMAD3 results in impaired mucosal immunity and diminished T cell responsiveness to TGF-beta

6 July 2018

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Alternatively spliced variant of Smad2 lacking exon 3. Comparison with wild-type Smad2 and Smad3.

6 July 2018

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SMAD3/4-dependent transcriptional activation of the human type VII collagen gene (COL7A1) promoter by transforming growth factor beta.

6 July 2018

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Smad2 role in mesoderm formation, left-right patterning and craniofacial development

6 July 2018

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Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene

6 July 2018

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Targeted disruption of Smad3 confers resistance to the development of dimethylnitrosamine-induced hepatic fibrosis in mice.

6 July 2018

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Disruption of the Smad7 gene promotes renal fibrosis and inflammation in unilateral ureteral obstruction (UUO) in mice.

27 October 2018

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Essential role of Smad3 in infarct healing and in the pathogenesis of cardiac remodeling.

27 October 2018

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Inhibition of renal fibrosis by gene transfer of inducible Smad7 using ultrasound-microbubble system in rat UUO model

27 October 2018

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Epithelial-specific Cre/lox recombination in the developing kidney and genitourinary tract.

27 October 2018

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Smad3 deficiency attenuates bleomycin-induced pulmonary fibrosis in mice

27 October 2018

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Transforming growth factor-beta repression of matrix metalloproteinase-1 in dermal fibroblasts involves Smad3.

27 October 2018

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Functional characterization of transforming growth factor beta signaling in Smad2- and Smad3-deficient fibroblasts

27 October 2018

1 reference

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CTGF and SMADs, maintenance of scleroderma phenotype is independent of SMAD signaling

27 October 2018

1 reference

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Stimulation of Type I Collagen Transcription in Human Skin Fibroblasts by TGF-β: Involvement of Smad 3

27 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20595680

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

It's a Smad world: regulation of TGF-beta signaling in the kidney

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20595680

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1681/ASN.2009121244

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20595680%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20595680%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

1 reference