Evidence of oxidative damage in Alzheimer's disease brain: central role for amyloid beta-peptide (Q34456855)

2 August 2017

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title

Evidence of oxidative damage in Alzheimer's disease brain: central role for amyloid beta-peptide (English)

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2 August 2017

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Butterfield DA

1

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2 August 2017

Drake J

series ordinal

2

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2 August 2017

Pocernich C

series ordinal

3

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2 August 2017

Castegna A

series ordinal

4

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2 August 2017

1 December 2001

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Trends in Molecular Medicine

2 August 2017

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2 August 2017

7

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2 August 2017

548-554

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2 August 2017

12

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Advances in Alzheimer's disease

2 August 2017

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https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902173-6

7 January 2021

Amyloid beta-protein and the genetics of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902173-6

7 January 2021

In vivo neurotoxicity of beta-amyloid [beta(1-40)] and the beta(25-35) fragment

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https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902173-6

7 January 2021

Nerve growth factor potentiates the neurotoxicity of beta amyloid

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902173-6

7 January 2021

beta-Amyloid induces neuritic dystrophy in vitro: similarities with Alzheimer pathology

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https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902173-6

7 January 2021

beta-Amyloid-associated free radical oxidative stress and neurotoxicity: implications for Alzheimer's disease

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https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902173-6

7 January 2021

Review: Alzheimer's amyloid beta-peptide-associated free radical oxidative stress and neurotoxicity

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https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902173-6

7 January 2021

Oxidative stress hypothesis in Alzheimer's disease

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https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902173-6

7 January 2021

Impairment of membrane transport and signal transduction systems by amyloidogenic proteins.

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https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902173-6

7 January 2021

Role of spermine in amyloid beta-peptide-associated free radical-induced neurotoxicity

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https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902173-6

7 January 2021

The glial glutamate transporter, GLT-1, is oxidatively modified by 4-hydroxy-2-nonenal in the Alzheimer's disease brain: the role of Abeta1-42.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902173-6

7 January 2021

RAGE and amyloid-beta peptide neurotoxicity in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902173-6

7 January 2021

Neuroinflammatory signaling upregulation in Alzheimer's disease

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https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902173-6

7 January 2021

Apolipoprotein E modulates Alzheimer's Abeta(1-42)-induced oxidative damage to synaptosomes in an allele-specific manner

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https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902173-6

7 January 2021

Evidence for a membrane defect in Alzheimer disease brain

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https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902173-6

7 January 2021

Regional membrane phospholipid alterations in Alzheimer's disease.

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https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902173-6

7 January 2021

Vitamin E protects against Alzheimer's amyloid peptide (25-35)-induced changes in neocortical synaptosomal membrane lipid structure and composition.

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https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902173-6

7 January 2021

Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes

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https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902173-6

7 January 2021

Four-hydroxynonenal, a product of lipid peroxidation, is increased in the brain in Alzheimer's disease.

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https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902173-6

7 January 2021

4-hydroxy-2-nonenal pyrrole adducts in human neurodegenerative disease.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902173-6

7 January 2021

4-Hydroxynonenal, a product of lipid peroxidation, damages cholinergic neurons and impairs visuospatial memory in rats

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902173-6

7 January 2021

Glutathione elevation and its protective role in acrolein-induced protein damage in synaptosomal membranes: relevance to brain lipid peroxidation in neurodegenerative disease

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902173-6

7 January 2021

Protein-bound acrolein: a novel marker of oxidative stress in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902173-6

7 January 2021

Acrolein is increased in Alzheimer's disease brain and is toxic to primary hippocampal cultures

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902173-6

7 January 2021

Peroxynitrite-induced alterations in synaptosomal membrane proteins: insight into oxidative stress in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902173-6

7 January 2021

Decreased glutathione transferase activity in brain and ventricular fluid in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902173-6

7 January 2021

Formation of isoprostane-like compounds (neuroprostanes) in vivo from docosahexaenoic acid.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902173-6

7 January 2021

Cerebrospinal fluid F2-isoprostane levels are increased in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902173-6

7 January 2021

Characterization of 8-epiprostaglandin F2alpha as a marker of amyloid beta-peptide-induced oxidative damage.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902173-6

7 January 2021

The magnitude of brain lipid peroxidation correlates with the extent of degeneration but not with density of neuritic plaques or neurofibrillary tangles or with APOE genotype in Alzheimer's disease patients

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902173-6

7 January 2021

Brain regional quantification of F-ring and D-/E-ring isoprostanes and neuroprostanes in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902173-6

7 January 2021

beta-Amyloid peptide free radical fragments initiate synaptosomal lipoperoxidation in a sequence-specific fashion: implications to Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902173-6

7 January 2021

Protein oxidation and aging

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https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902173-6

7 January 2021

Free radical oxidation of brain proteins in accelerated senescence and its modulation by N-tert-butyl-alpha-phenylnitrone

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902173-6

7 January 2021

Biochemistry and pathology of radical-mediated protein oxidation

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https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902173-6

7 January 2021

Amyloid beta-peptide-associated free radical oxidative stress, neurotoxicity, and Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902173-6

7 January 2021

Oxidation of cytosolic proteins and expression of creatine kinase BB in frontal lobe in different neurodegenerative disorders.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902173-6

7 January 2021

An assessment of oxidative damage to proteins, lipids, and DNA in brain from patients with Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902173-6

7 January 2021

Brain regional correspondence between Alzheimer's disease histopathology and biomarkers of protein oxidation.

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https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902173-6

7 January 2021

Protein oxidation in the brain in Alzheimer's disease

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https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902173-6

7 January 2021

Oxidative damage in Alzheimer's.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902173-6

7 January 2021

Oxidative modification of creatine kinase BB in Alzheimer's disease brain.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902173-6

7 January 2021

Oxidatively induced structural alteration of glutamine synthetase assessed by analysis of spin label incorporation kinetics: relevance to Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902173-6

7 January 2021

Oxidative modification of glutamine synthetase by amyloid beta peptide.

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https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902173-6

7 January 2021

Oxidative chemistry of peroxynitrite

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https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902173-6

7 January 2021

Electrochemical analysis of protein nitrotyrosine and dityrosine in the Alzheimer brain indicates region-specific accumulation.

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https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902173-6

7 January 2021

Widespread peroxynitrite-mediated damage in Alzheimer's disease.

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https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902173-6

7 January 2021

Decreased thioredoxin and increased thioredoxin reductase levels in Alzheimer's disease brain.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902173-6

7 January 2021

Oxidative damage and protection by antioxidants in the frontal cortex of Alzheimer's disease is related to the apolipoprotein E genotype.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902173-6

7 January 2021

Vulnerability of synaptosomes from apoE knock-out mice to structural and oxidative modifications induced by A beta(1-40): implications for Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902173-6

7 January 2021

Methionine residues as endogenous antioxidants in proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902173-6

7 January 2021

Decrease in peptide methionine sulfoxide reductase in Alzheimer's disease brain.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902173-6

7 January 2021

Oxidative damage to mitochondrial DNA is increased in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902173-6

7 January 2021

Increased nuclear DNA oxidation in the brain in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902173-6

7 January 2021

RNA oxidation is a prominent feature of vulnerable neurons in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902173-6

7 January 2021

Mitochondrial DNA damage as a mechanism of cell loss in Alzheimer's disease.

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https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902173-6

7 January 2021

Mitochondrial abnormalities in Alzheimer's disease.

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https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902173-6

7 January 2021

Ratio of 8-hydroxyguanine in intact DNA to free 8-hydroxyguanine is increased in Alzheimer disease ventricular cerebrospinal fluid

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https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902173-6

7 January 2021

Increased levels of DNA breaks in cerebral cortex of Alzheimer's disease patients

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https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902173-6

7 January 2021

Neuronal DNA damage precedes tangle formation and is associated with up-regulation of nitrotyrosine in Alzheimer's disease brain.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902173-6

7 January 2021

Decreased base excision repair and increased helicase activity in Alzheimer's disease brain.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902173-6

7 January 2021

Increased poly(ADP-ribosyl)ation of nuclear proteins in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902173-6

7 January 2021

Fibrillar Alzheimer's amyloid peptide Abeta(1-42) stimulates low density lipoprotein binding and cell association, free radical production and cell cytotoxicity in PC12 cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902173-6

7 January 2021

Different mechanisms of oxidative stress and neurotoxicity for Alzheimer's A beta(1--42) and A beta(25--35).

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https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902173-6

7 January 2021

Perturbed endoplasmic reticulum function, synaptic apoptosis and the pathogenesis of Alzheimer's disease.

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https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902173-6

7 January 2021

Alzheimer's disease amyloid-beta binds copper and zinc to generate an allosterically ordered membrane-penetrating structure containing superoxide dismutase-like subunits

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902173-6

7 January 2021

Neurotoxic Abeta peptides increase oxidative stress in vivo through NMDA-receptor and nitric-oxide-synthase mechanisms, and inhibit complex IV activity and induce a mitochondrial permeability transition in vitro

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https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902173-6

7 January 2021

Fibrillar beta-amyloid evokes oxidative damage in a transgenic mouse model of Alzheimer's disease

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https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902173-6

7 January 2021

Brain oxidative stress in animal models of accelerated aging and the age-related neurodegenerative disorders, Alzheimer's disease and Huntington's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902173-6

7 January 2021

10.1016/S1471-4914(01)02173-6

Identifiers

DOI

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2 August 2017

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