Selective inactivation of USP18 isopeptidase activity in vivo enhances ISG15 conjugation and viral resistance (Q34458906)

2 August 2017

Selective inactivation of USP18 isopeptidase activity in vivo enhances ISG15 conjugation and viral resistance (English)

1 reference

2 August 2017

11

Olaf Utermöhlen

1 reference

2 August 2017

Lars Ketscher

1

0 references

Tobias Goldmann

object named as

Tobias Goldmann

6

0 references

Andrew Pekosz

object named as

Andrew Pekosz

10

0 references

Deborah J. Lenschow

12

object named as

Deborah J Lenschow

1 reference

2 August 2017

8

Marco Prinz

1 reference

2 August 2017

Annika Hausmann

7

0 references

author name string

Ronny Hannß

2

1 reference

2 August 2017

David J Morales

3

1 reference

2 August 2017

Anja Basters

4

1 reference

2 August 2017

Susana Guerra

5

1 reference

2 August 2017

Ronald Naumann

9

1 reference

2 August 2017

Klaus-Peter Knobeloch

13

1 reference

2 August 2017

language of work or name

English

0 references

publication date

20 January 2015

1 reference

Proceedings of the National Academy of Sciences of the United States of America

2 August 2017

1 reference

2 August 2017

112

1 reference

2 August 2017

5

1 reference

2 August 2017

1577-1582

1 reference

ISG15 is counteracted by vaccinia virus E3 protein and controls the proinflammatory response against viral infection

2 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321242

Ubiquitin-specific protease-like 1 (USPL1) is a SUMO isopeptidase with essential, non-catalytic functions

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321242

HERC6 is the main E3 ligase for global ISG15 conjugation in mouse cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321242

mHERC6 is the essential ISG15 E3 ligase in the murine system

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321242

Enforced viral replication activates adaptive immunity and is essential for the control of a cytopathic virus

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321242

USP18-based negative feedback control is induced by type I and type III interferons and specifically inactivates interferon α response

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321242

Toll-like receptors and their crosstalk with other innate receptors in infection and immunity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321242

Polyubiquitin binding and cross-reactivity in the USP domain deubiquitinase USP21

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321242

N-ethyl-N-nitrosourea-induced mutation in ubiquitin-specific peptidase 18 causes hyperactivation of IFN-αß signaling and suppresses STAT4-induced IFN-γ production, resulting in increased susceptibility to Salmonella typhimurium

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321242

The ISG15 conjugation system broadly targets newly synthesized proteins: implications for the antiviral function of ISG15.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321242

Positive regulation of interferon regulatory factor 3 activation by Herc5 via ISG15 modification

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321242

ISG15 conjugation system targets the viral NS1 protein in influenza A virus-infected cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321242

Breaking the chains: structure and function of the deubiquitinases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321242

Alpha Interferon Induces Long-Lasting Refractoriness of JAK-STAT Signaling in the Mouse Liver through Induction of USP18/UBP43

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321242

ISG15 Arg151 and the ISG15-conjugating enzyme UbE1L are important for innate immune control of Sindbis virus

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321242

Vaccinia virus E3 protein prevents the antiviral action of ISG15

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321242

Interferon-inducible antiviral effectors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321242

Ovarian tumor domain-containing viral proteases evade ubiquitin- and ISG15-dependent innate immune responses

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321242

Screen for ISG15-crossreactive deubiquitinases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321242

IFN-stimulated gene 15 functions as a critical antiviral molecule against influenza, herpes, and Sindbis viruses

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321242

ISG15 enhances the innate antiviral response by inhibition of IRF-3 degradation.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321242

HERC5 is an IFN-induced HECT-type E3 protein ligase that mediates type I IFN-induced ISGylation of protein targets

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321242

UBP43 is a novel regulator of interferon signaling independent of its ISG15 isopeptidase activity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321242

Herc5, an interferon-induced HECT E3 enzyme, is required for conjugation of ISG15 in human cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321242

Ube1L and protein ISGylation are not essential for alpha/beta interferon signaling

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321242

Reexamination of the role of ubiquitin-like modifier ISG15 in the phenotype of UBP43-deficient mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321242

ISG15, an interferon-stimulated ubiquitin-like protein, is not essential for STAT1 signaling and responses against vesicular stomatitis and lymphocytic choriomeningitis virus

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321242

The UbcH8 ubiquitin E2 enzyme is also the E2 enzyme for ISG15, an IFN-alpha/beta-induced ubiquitin-like protein

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321242

Protein ISGylation modulates the JAK-STAT signaling pathway

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321242

Chemistry-based functional proteomics reveals novel members of the deubiquitinating enzyme family

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321242

Dysregulation of protein modification by ISG15 results in brain cell injury

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321242

UBP43 (USP18) specifically removes ISG15 from conjugated proteins

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321242

Influenza B virus NS1 protein inhibits conjugation of the interferon (IFN)-induced ubiquitin-like ISG15 protein

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4321242

Mice lacking the ISG15 E1 enzyme UbE1L demonstrate increased susceptibility to both mouse-adapted and non-mouse-adapted influenza B virus infection

6 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1412881112

Role of ISG15 protease UBP43 (USP18) in innate immunity to viral infection.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1412881112

Growth and differentiation of mouse tracheal epithelial cells: selection of a proliferative population.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1412881112

Crystal structure of the interferon-induced ubiquitin-like protein ISG15

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25605921

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1412881112

1 reference

2 August 2017

0 references

1 reference

2 August 2017

1 reference