Synergistic mechanisms in carcinogenesis by polycyclic aromatic hydrocarbons and by tobacco smoke: a bio-historical perspective with updates (Q34467367)

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English	Synergistic mechanisms in carcinogenesis by polycyclic aromatic hydrocarbons and by tobacco smoke: a bio-historical perspective with updates	scientific article

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scholarly article

1 reference

Europe PubMed Central

2 August 2017

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Europe PubMed Central

Synergistic mechanisms in carcinogenesis by polycyclic aromatic hydrocarbons and by tobacco smoke: a bio-historical perspective with updates (English)

1 reference

Europe PubMed Central

2 August 2017

0 references

1 reference

based on heuristic

inferred from title

polycyclic aromatic hydrocarbons

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based on heuristic

inferred from title

author name string

H Rubin

1

1 reference

Europe PubMed Central

2 August 2017

language of work or name

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publication date

1 December 2001

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Europe PubMed Central

2 August 2017

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Europe PubMed Central

2 August 2017

22

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Europe PubMed Central

2 August 2017

12

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Europe PubMed Central

2 August 2017

1903-1930

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Europe PubMed Central

2 August 2017

Fifty years of benzo(a)pyrene

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21 January 2018

Polynuclear aromatic hydrocarbons, steroids and carcinogenesis.

1 reference

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21 January 2018

EVIDENCE FOR THE BINDING OF POLYNUCLEAR AROMATIC HYDROCARBONS TO THE NUCLEIC ACIDS OF MOUSE SKIN: RELATION BETWEEN CARCINOGENIC POWER OF HYDROCARBONS AND THEIR BINDING TO DEOXYRIBONUCLEIC ACID.

1 reference

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21 January 2018

Metabolic conversion of benzo[a]pyrene by Syrian hamster liver microsomes and binding of metabolites to deoxyribonucleic acid

1 reference

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21 January 2018

A metabolite of the carcinogen 7,12-dimethylbenz[a]anthracene that reacts predominantly with adenine residues in DNA.

1 reference

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21 January 2018

Stereoselective activation of dibenzo[a,l]pyrene to (-)-anti (11R,12S,13S,14R)- and (+)-syn(11S,12R,13S,14R)-11,12-diol-13,14-epoxides which bind extensively to deoxyadenosine residues of DNA in the human mammary carcinoma cell line MCF-7.

1 reference

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21 January 2018

The role of croton oil applications, associated with a single painting of a carcinogen, in tumour induction of the mouse's skin

1 reference

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21 January 2018

A new, quantitative, approach to the study of the stages of chemical cartinogenesis in the mouse's skin

1 reference

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21 January 2018

An experimental study of the initiating state of carcinogenesis, and a re-examination of the somatic cell mutation theory of cancer

1 reference

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21 January 2018

Papillomas induced by initiation-promotion differ from those induced by carcinogen alone.

1 reference

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21 January 2018

Selective nature of phorbol 12-myristate 13-acetate-induced neoplastic transformation in NIH 3T3 cells

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21 January 2018

Carcinogens are mutagens: a simple test system combining liver homogenates for activation and bacteria for detection

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21 January 2018

Tumour-initiating activities on mouse skin of dihydrodiols derived from benzo[a]pyrene

1 reference

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21 January 2018

The initiation of tumours on mouse skin by dihydrodiols derived from 7,12-dimethylbenz(a)anthracene and 3-methylcholanthrene

1 reference

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21 January 2018

The importance of the “bay region” diol-epoxide in 7,12-dimethylbenz[a]anthracene skin tumor initiation and mutagenesis

1 reference

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21 January 2018

The approach to understanding aromatic hydrocarbon carcinogenesis. The central role of radical cations in metabolic activation

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21 January 2018

The role of the hair follicle in the origin and evolution of some cutaneous neoplasms of man and experimental animals

1 reference

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21 January 2018

Epidermal stem cells: properties, markers, and location.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F22.12.1903

21 January 2018

High mutagenicity and toxicity of a diol epoxide derived from benzo(a)pyrene

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F22.12.1903

21 January 2018

Identification of mutagenic metabolites of benzo(a)pyrene in mammalian cells

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F22.12.1903

21 January 2018

Benzo[a]pyrene 7,8-dihydrodiol is more carcinogenic than benzo[a]pyrene in newborn mice

1 reference

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21 January 2018

Tumor-initiating activity and carcinogenicity of dibenzo[a,l]pyrene versus 7,12-dimethylbenz[a]anthracene and benzo[a]pyrene at low doses in mouse skin.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F22.12.1903

21 January 2018

The binding to mouse skin DNA of benzo[a]pyrene, its 7,8-diol and 7,8-diol-9,10-epoxides in relation to the tumourigenicity of these compounds

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F22.12.1903

21 January 2018

Comparison of levels of benzo[a]pyrene diol epoxide diastereomers covalently bound in vivo to macromolecular components of the whole epidermis versus the basal cell layer

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F22.12.1903

21 January 2018

Tumorigenicity of the optical enantiomers of the diastereomeric benzo[a]pyrene 7,8-diol-9,10-epoxides in newborn mice: exceptional activity of (+)-7beta,8alpha-dihydroxy-9alpha,10alpha-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F22.12.1903

21 January 2018

Quantitative assay for carcinogen altered differentiation in mouse epidermal cells

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F22.12.1903

21 January 2018

Expression of transformed morphology and anchorage independent growth of hamster embryo cells.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F22.12.1903

21 January 2018

Mutagenicity to mammalian cells of epoxides and other derivatives of polycyclic hydrocarbons

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F22.12.1903

21 January 2018

Epoxides of Carcinogenic Polycyclic Hydrocarbons Are Frameshift Mutagens

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F22.12.1903

21 January 2018

The carcinogenic activities in mice of compounds related to 3-methylcholanthrene.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F22.12.1903

21 January 2018

In vitro transformation of rodent cells by K-region derivatives of polycyclic hydrocarbons

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F22.12.1903

21 January 2018

Malignant transformationin vitro of mouse fibroblasts by 7, 12-dimethylbenz(A)anthracene and 7-hydroxymethylbenz(A)anthracene and by their K-region derivatives

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F22.12.1903

21 January 2018

The rate of disappearance of 3:4-benzpyrene from the mouse after subcutaneous and intraperitoneal injection

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F22.12.1903

21 January 2018

Non-mutagenic carcinogens are primarily hydrophobic.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F22.12.1903

21 January 2018

Aneuploidy, an early event in mouse skin tumor development

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F22.12.1903

21 January 2018

Chromosome breakage induced by a carcinogenic hydrocarbon in Chinese hamster cells and human leukocytes in vitro

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F22.12.1903

21 January 2018

Prooxidant states and tumor promotion

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F22.12.1903

21 January 2018

Carcinogen-induced chromosomal breakage decreased by antioxidants

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F22.12.1903

21 January 2018

CONDITIONAL NEOPLASMS AND SUBTHRESHOLD NEOPLASTIC STATES : A STUDY OF THE TAR TUMORS OF RABBITS.

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21 January 2018

THE EXPERIMENTAL DISCLOSURE OF LATENT NEOPLASTIC CHANGES IN TARRED SKIN.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F22.12.1903

21 January 2018

THE INITIATING AND PROMOTING ELEMENTS IN TUMOR PRODUCTION : AN ANALYSIS OF THE EFFECTS OF TAR, BENZPYRENE, AND METHYLCHOLANTHRENE ON RABBIT SKIN.

1 reference

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21 January 2018

The persistence of latent tumour cells induced in the mouse's skin by a single application of 9:10-dimethyl-1:2-benzanthracene

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F22.12.1903

21 January 2018

Somatic spectrum of cancer-associated single basepair substitutions in the TP53 gene is determined mainly by endogenous mechanisms of mutation and by selection

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F22.12.1903

21 January 2018

Tumor Promoters: Carcinogenesis Gets More Complicated

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F22.12.1903

21 January 2018

v-ras genes from Harvey and BALB murine sarcoma viruses can act as initiators of two-stage mouse skin carcinogenesis.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F22.12.1903

21 January 2018

In vitro establishment is not a sufficient prerequisite for transformation by activated ras oncogenes.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F22.12.1903

21 January 2018

Studies on the mechanism of skin tumor promotion: evidence for several stages in promotion

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F22.12.1903

21 January 2018

Skin tumor promotion by phorbol esters is a two-stage process

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F22.12.1903

21 January 2018

Tumor promotion by phorbol esters in skin: evidence for a memory effect.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F22.12.1903

21 January 2018

Partial inversion of the initiation-promotion sequence of multistage tumorigenesis in the skin of NMRI mice.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F22.12.1903

21 January 2018

DNA Strand Breakage in Human Leukocytes Exposed to a Tumor Promoter, Phorbol Myristate Acetate

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F22.12.1903

21 January 2018

Tumor promoter 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced chromosome aberrations in mouse keratinocyte cell lines: a possible genetic mechanism of tumor promotion

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F22.12.1903

21 January 2018

Cytogenetic effects caused by phorbol ester tumor promoters in primary mouse keratinocyte cultures: correlation with the convertogenic activity of TPA in multistage skin carcinogenesis

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F22.12.1903

21 January 2018

Tumor induction in initiated mouse skin by phorbol esters and methyl methanesulfonate: correlation between chromosomal damage and conversion ('stage I of tumor promotion') in vivo

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F22.12.1903

21 January 2018

Three-stage tumorigenesis in mouse skin: DNA synthesis as a prerequisite for the conversion stage induced by TPA prior to initiation

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F22.12.1903

21 January 2018

Stimulatory role of transforming growth factors in multistage skin carcinogenesis: possible explanation for the tumor-inducing effect of wounding in initiated NMRI mouse skin

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F22.12.1903

21 January 2018

Chromosomal aberrations as a contributing factor for tumor promotion in the mouse skin

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F22.12.1903

21 January 2018

Defective responses of transformed keratinocytes to terminal differentiation stimuli. Their role in epidermal tumour promotion by phorbol esters and by deep skin wounding

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F22.12.1903

21 January 2018

The conversion stage of skin carcinogenesis

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F22.12.1903

21 January 2018

The effects of weak or non-carcinogenic polycyclic hydrocarbons on 7, 12-dimethylbenz[a]anthracene and benzo[a]pyrene skin tumor-initiation

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F22.12.1903

21 January 2018

Retinoyl-phorbol-acetate is a complete skin tumor promoter in SENCAR mice

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21 January 2018

Correlation between sensitivity to tumor promotion and sustained epidermal hyperplasia of mice and rats treated with 12-O-tetra-decanoylphorbol-13-acetate.

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21 January 2018

Evidence for the progressive and adaptive nature of spontaneous transformation in the NIH 3T3 cell line

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21 January 2018

Induction of pseudofoci and inhibition of density-mediated neoplastic transformation by PMA in NIH 3T3 cells after short-term exposures

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21 January 2018

Integration of a mutant c-Ha-ras oncogene into C3H/10T1/2 cells and its relationship to tumorigenic transformation

1 reference

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21 January 2018

Tobacco smoking as a possible etiologic factor in bronchiogenic carcinoma; a study of 684 proved cases

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21 January 2018

Smoking and carcinoma of the lung; preliminary report

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21 January 2018

A study of tobacco carcinogenesis. II. Dose-response studies.

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21 January 2018

A study of tobacco carcinogenesis. I. The primary fractions.

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21 January 2018

Effect of concentration of benzopyrene in skin carcinogenesis.

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21 January 2018

A study of tobacco carcinogenesis. VII. The role of higher polycyclic hydrocarbons.

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21 January 2018

The development of malignant tumours of mouse skin after initiating and promoting stimuli. III. The carcinogenic action of croton oil.

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21 January 2018

Incomplete Carcinogens in Cigarette Smoke Condensate: Tumour-Promotion by a Phenolic Fraction

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21 January 2018

Incomplete carcinogens: ethyl carbamate (urethane) as an initiator of skin tumour formation in the mouse

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21 January 2018

Further Studies on Incomplete Carcinogenesis: Triethylene Melamine (T.E.M.), 1,2-Benzanthracene and β-Propiolactone, as Initiators of Skin Tumour Formation in the Mouse

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21 January 2018

A study of tobacco carcinogenesis. VIII. The role of the acidic fractions as promoters.

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21 January 2018

A study of tobacco carcinogenesis. X. Tumor promoting activity.

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21 January 2018

TUMOR-PROMOTING ACTIVITY OF EXTRACTS OF UNBURNED TOBACCO.

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21 January 2018

Carcinogenic constituents of coal-tar

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21 January 2018

Covalent binding of polycyclic aromatic hydrocarbon components of coal tar to DNA in mouse skin.

1 reference

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21 January 2018

The carcinogenicity of environmental tobacco smoke

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21 January 2018

The carcinogenic potential of the gas phase of environmental tobacco smoke

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21 January 2018

Successful and not so successful chemoprevention of tobacco smoke-induced lung tumors.

1 reference

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21 January 2018

Preferential formation of benzo[a]pyrene adducts at lung cancer mutational hotspots in P53.

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21 January 2018

p53 mutations, benzo[a]pyrene and lung cancer.

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21 January 2018

Human lung cancer and p53: the interplay between mutagenesis and selection

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21 January 2018

Patterns of p53 G-->T transversions in lung cancers reflect the primary mutagenic signature of DNA-damage by tobacco smoke

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21 January 2018

Tobacco-specific nitrosamines, an important group of carcinogens in tobacco and tobacco smoke.

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21 January 2018

Tobacco smoke carcinogens and lung cancer

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21 January 2018

Cigarette smoking and changes in the histopathology of lung cancer

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21 January 2018

Differential response of Snell's and C57 black mice to chronic inhalation of cigarette smoke. Pulmonary carcinogenesis and vascular alterations in lung and heart.

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21 January 2018

Lung tumors in strain A mice as a bioassay for carcinogenicity of environmental chemicals

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21 January 2018

Mechanistic linkage between DNA adducts, mutations in oncogenes and tumorigenesis of carcinogenic environmental polycyclic aromatic hydrocarbons in strain A/J mice.

1 reference

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21 January 2018

Six-month exposure of strain A/J mice to cigarette sidestream smoke: cell kinetics and lung tumor data

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21 January 2018

Failure of cigarette smoke to induce or promote lung cancer in the A/J mouse.

1 reference

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21 January 2018

DNA damage in human respiratory tract epithelial cells: damage by gas phase cigarette smoke apparently involves attack by reactive nitrogen species in addition to oxygen radicals

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21 January 2018

Comparative carcinogenicity of cigarette mainstream and sidestream smoke condensates on the mouse skin.

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21 January 2018

Cigarette Smoke Inhalation Studies in Inbred Syrian Golden Hamsters2

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21 January 2018

Carcinogenesis by Cholesterol

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21 January 2018

Effect of dose fractionation on the enhancement by radiation or cyclophosphamide of artificial pulmonary metastases

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21 January 2018

Distinct spectra of somatic mutations accumulated with age in mouse heart and small intestine

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21 January 2018

Lessons from hereditary colorectal cancer

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21 January 2018

Elimination of Metabolic Cooperation in Chinese Hamster Cells by a Tumor Promoter

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21 January 2018

Activity of benzo[a]pyrene and its hydroxylated metabolites in an estrogen receptor-alpha reporter gene assay

1 reference

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21 January 2018

Polynuclear aromatic hydrocarbon carcinogens as antiestrogens in MCF-7 human breast cancer cells: role of the Ah receptor

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21 January 2018

On the Origin of Cancer Cells

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21 January 2018

On respiratory impairment in cancer cells

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21 January 2018

The action of steroids and streptolysin S on the permeability of phospholipid structures to cations

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21 January 2018

Keilin's Respiratory Chain Concept and Its Chemiosmotic Consequences

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21 January 2018

The mutation rate and cancer

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21 January 2018

Metabolic activation of benzo(a)pyrene proceeds by a diol-epoxide

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21 January 2018

Malignant conversion of mouse skin tumours is increased by tumour initiators and unaffected by tumour promoters

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21 January 2018

Penetration of Benzpyrene through the Intact Skin of New-Born Mice

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21 January 2018

Uptake of Hydrocarbon Carcinogens by Lysosomes

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21 January 2018

Tumour-promoting Agents in Unburned Cigarette Tobacco

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21 January 2018

Identifiers

10.1093/CARCIN/22.12.1903

1 reference

Europe PubMed Central

2 August 2017

1 reference

Europe PubMed Central

2 August 2017

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