Human lung cancer and p53: the interplay between mutagenesis and selection (Q35413576)

8 August 2017

Human lung cancer and p53: the interplay between mutagenesis and selection (English)

1 reference

8 August 2017

1 reference

S N Rodin

1

1 reference

PubMed ID

11035769

8 August 2017

A S Rodin

series ordinal

2

1 reference

PubMed ID

11035769

8 August 2017

language of work or name

English

0 references

publication date

1 October 2000

1 reference

Proceedings of the National Academy of Sciences of the United States of America

8 August 2017

1 reference

8 August 2017

97

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8 August 2017

22

1 reference

8 August 2017

12244-12249

1 reference

IARC p53 mutation database: a relational database to compile and analyze p53 mutations in human tumors and cell lines. International Agency for Research on Cancer

8 August 2017

1 reference

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Influence of sex, smoking and age on human hprt mutation frequencies and spectra

27 July 2018

1 reference

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Molecular epidemiology of human cancer risk: gene-environment interactions and p53 mutation spectrum in human lung cancer

27 July 2018

1 reference

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Smoking and carcinoma of the lung. Preliminary report. 1950.

27 July 2018

1 reference

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Strand asymmetry of CpG transitions as indicator of G1 phase-dependent origin of multiple tumorigenic p53 mutations in stem cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17326

A specific spectrum of p53 mutations in lung cancer from smokers: review of mutations compiled in the IARC p53 database

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17326

Hypermutability in carcinogenesis

27 July 2018

1 reference

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A model for p53-induced apoptosis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17326

Somatic mutation theory, DNA repair rates, and the molecular epidemiology of p53 mutations

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17326

Distribution of p53 and K-ras mutations in human lung cancer tissues

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17326

p53, the cellular gatekeeper for growth and division

27 July 2018

1 reference

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The Croonian Lecture, 1996: endogenous damage to DNA.

27 July 2018

1 reference

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Cancer risk and oxidative DNA damage in man.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17326

Preferential formation of benzo[a]pyrene adducts at lung cancer mutational hotspots in P53.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17326

Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17326

Benzo[a]pyrene-induced murine skin tumors exhibit frequent and characteristic G to T mutations in the p53 gene

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17326

N-nitroso-N-methylurea-induced rat mammary tumors arise from cells with preexisting oncogenic Hras1 gene mutations

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17326

Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17326

Tobacco and cancer: epidemiology and the laboratory

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17326

Software for the analysis of mutations at the human hprt gene.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17326

Statistical test for the comparison of samples from mutational spectra

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17326

Ability of adducts formed in a shuttle vector by reactive metabolites of 1-nitropyrene and benzo(a)pyrene to induce mutations when the plasmid replicates in human cells.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17326

p53 mutations, benzo[a]pyrene and lung cancer: a reply

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17326

CpG transition strand asymmetry and hitch-hiking mutations as measures of tumorigenic selection in shaping the p53 mutation spectrum

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17326

p53 mutations, benzo[a]pyrene and lung cancer.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17326

p53 mutations in non-small-cell lung cancers occurring in individuals without a past history of active smoking

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17326

Mutation and cancer: the antecedents to our studies of adaptive mutation.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17326

Slow repair of bulky DNA adducts along the nontranscribed strand of the human p53 gene may explain the strand bias of transversion mutations in cancers.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17326

p53 mediates permanent arrest over multiple cell cycles in response to gamma-irradiation.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17326

5-Methylcytosine as an Endogenous Mutagen in the Human LDL Receptor and p53 Genes

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17326

In vitro and in vivo genotoxicity evaluation of hormonal drugs v. mestranol.

26 September 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.180320897

Selection, the mutation rate and cancer: Ensuring that the tail does not wag the dog

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.180320897

Somatic spectrum of cancer-associated single basepair substitutions in the TP53 gene is determined mainly by endogenous mechanisms of mutation and by selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.180320897

Life (and death) in a malignant tumour

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.180320897

The influence of formamidopyrimidine-DNA glycosylase on the spontaneous and gamma-radiation-induced mutation spectrum of the lacZ alpha gene

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11035769

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Comparison of mutations in the p53 and K-ras genes in lung carcinomas from smoking and nonsmoking women

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11035769

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.180320897

1 reference

8 August 2017

0 references

1 reference

8 August 2017

1 reference

PubMed ID

11035769