Control of T helper cell differentiation--in search of master genes (Q34467702)

2 August 2017

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title

Control of T helper cell differentiation--in search of master genes (English)

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2 August 2017

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2

Flavell RA

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2 August 2017

Dong C

1

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2 August 2017

12 September 2000

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Science's STKE : signal transduction knowledge environment

2 August 2017

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2 August 2017

2000

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2 August 2017

pe1

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2 August 2017

49

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Reprogramming the signalling requirement for AP-1 (activator protein-1) activation during differentiation of precursor CD4+ T-cells into effector Th1 and Th2 cells.

2 August 2017

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.49.PE1

Transcription mediated by NFAT is highly inducible in effector CD4+ T helper 2 (Th2) cells but not in Th1 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.49.PE1

The NFAT-1 DNA binding complex in activated T cells contains Fra-1 and JunB.

21 January 2018

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https://api.crossref.org/works/10.1126%2FSTKE.2000.49.PE1

An enhanced immune response in mice lacking the transcription factor NFAT1.

21 January 2018

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https://api.crossref.org/works/10.1126%2FSTKE.2000.49.PE1

Transcription factor GATA-3 is differentially expressed in murine Th1 and Th2 cells and controls Th2-specific expression of the interleukin-5 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.49.PE1

The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.49.PE1

The proto-oncogene c-maf is responsible for tissue-specific expression of interleukin-4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.49.PE1

c-maf promotes T helper cell type 2 (Th2) and attenuates Th1 differentiation by both interleukin 4-dependent and -independent mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.49.PE1

Th2-specific DNase I-hypersensitive sites in the murine IL-13 and IL-4 intergenic region.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.49.PE1

Identification of a Coordinate Regulator of Interleukins 4, 13, and 5 by Cross-Species Sequence Comparisons

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.49.PE1

Independent and epigenetic regulation of the interleukin-4 alleles in CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.49.PE1

Two essential regulatory elements in the human interferon gamma promoter confer activation specific expression in T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.49.PE1

Differential transcription directed by discrete gamma interferon promoter elements in naive and memory (effector) CD4 T cells and CD8 T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.49.PE1

The c-rel protooncogene product c-Rel but not NF-kappa B binds to the intronic region of the human interferon-gamma gene at a site related to an interferon-stimulable response element

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.49.PE1

A novel transcription factor, T-bet, directs Th1 lineage commitment

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.49.PE1

Essential role of Stat6 in IL-4 signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.49.PE1

Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.49.PE1

Control of inflammation, cytokine expression, and germinal center formation by BCL-6

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.49.PE1

T-cell subset-specific expression of the IL-4 gene is regulated by a silencer element and STAT6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.49.PE1

Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.49.PE1

Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.49.PE1

T cell antigen receptor-mediated activation of the Ras/mitogen-activated protein kinase pathway controls interleukin 4 receptor function and type-2 helper T cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.49.PE1

Interferon-gamma expression by Th1 effector T cells mediated by the p38 MAP kinase signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.49.PE1

Signal transduction by the c-Jun N-terminal kinase (JNK)--from inflammation to development

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.49.PE1

JNK is involved in signal integration during costimulation of T lymphocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.49.PE1

Regulation of c-Jun NH(2)-terminal kinase (Jnk) gene expression during T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.49.PE1

JNK is required for effector T-cell function but not for T-cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.49.PE1

AIB1 is a conduit for kinase-mediated growth factor signaling to the estrogen receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.49.PE1

The Proximal Regulatory Element of the Interferon-γ Promoter Mediates Selective Expression in T Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.49.PE1

Role of the Guanosine Triphosphatase Rac2 in T Helper 1 Cell Differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.49.PE1

21 January 2018

Identifiers

DOI

10.1126/STKE.2000.49.PE1

1 reference

2 August 2017

1 reference

PubMed ID

11752608