Clinical application of NKT cell assays to the prediction of type 1 diabetes (Q34470637)

2 August 2017

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title

Clinical application of NKT cell assays to the prediction of type 1 diabetes (English)

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2 August 2017

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Poulton LD

1

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2 August 2017

Baxter AG

series ordinal

2

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2 August 2017

language of work or name

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1 November 2001

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Diabetes - Metabolism: Research and Reviews

2 August 2017

published in

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2 August 2017

volume

17

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2 August 2017

issue

6

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2 August 2017

page(s)

429-435

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A secular increase in the incidence of juvenile diabetes mellitus

2 August 2017

cites work

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HLA-DQ beta gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus

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21 January 2018

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An invariant T cell receptor alpha chain is used by a unique subset of major histocompatibility complex class I-specific CD4+ and CD4-8- T cells in mice and humans.

21 January 2018

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Tracking the response of natural killer T cells to a glycolipid antigen using CD1d tetramers

21 January 2018

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In vivo identification of glycolipid antigen-specific T cells using fluorescent CD1d tetramers

21 January 2018

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CD4pos, NK1.1pos T cells promptly produce interleukin 4 in response to in vivo challenge with anti-CD3.

21 January 2018

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NK1.1+ T cells from IL-7-deficient mice have a normal distribution and selection but exhibit impaired cytokine production.

21 January 2018

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IL-4-producing NK T cells are biased towards IFN-gamma production by IL-12. Influence of the microenvironment on the functional capacities of NK T cells

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Increased interleukin 4 and immunoglobulin E production in transgenic mice overexpressing NK1 T cells.

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Suppression of in vivo polyclonal IgE responses by monoclonal antibody to the lymphokine B-cell stimulatory factor 1.

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Role of NK1.1+ T cells in a TH2 response and in immunoglobulin E production

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Impaired NK1+ T cell development and early IL-4 production in CD1-deficient mice.

21 January 2018

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Beta 2-microglobulin-dependent NK1.1+ T cells are not essential for T helper cell 2 immune responses

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An update on cytokines in the pathogenesis of insulin-dependent diabetes mellitus

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CD1-reactive natural killer T cells are required for development of systemic tolerance through an immune-privileged site.

21 January 2018

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Double negative (CD4-CD8- alpha beta+) T cells which promote tolerance induction and regulate autoimmunity

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Requirement for natural killer T (NKT) cells in the induction of allograft tolerance

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CD4(+) Valpha14 natural killer T cells are essential for acceptance of rat islet xenografts in mice

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The cells that knew too much

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Flow cytometric study of T cell development in NOD mice reveals a deficiency in alphabetaTCR+CDR-CD8- thymocytes.

21 January 2018

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alpha/beta-T cell receptor (TCR)+CD4-CD8- (NKT) thymocytes prevent insulin-dependent diabetes mellitus in nonobese diabetic (NOD)/Lt mice by the influence of interleukin (IL)-4 and/or IL-10.

21 January 2018

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Overexpression of natural killer T cells protects Valpha14- Jalpha281 transgenic nonobese diabetic mice against diabetes.

21 January 2018

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Germ line deletion of the CD1 locus exacerbates diabetes in the NOD mouse

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CD1-restricted NK T cells protect nonobese diabetic mice from developing diabetes

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Lipid antigen presentation in the immune system: lessons learned from CD1d knockout mice.

21 January 2018

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Extreme Th1 bias of invariant Valpha24JalphaQ T cells in type 1 diabetes.

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Multiple differences in gene expression in regulatory Valpha 24Jalpha Q T cells from identical twins discordant for type I diabetes

21 January 2018

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Natural T cells: cranking up the immune system by prompt cytokine secretion

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Heterophile antibodies segregate in families and are associated with protection from type 1 diabetes

21 January 2018

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Heterophile anti-mouse immunoglobulin antibodies may interfere with cytokine measurements in patients with HLA alleles protective for type 1A diabetes

21 January 2018

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Decreased secretion of Th2 cytokines precedes Up-regulated and delayed secretion of Th1 cytokines in activated peripheral blood mononuclear cells from patients with insulin-dependent diabetes mellitus.

21 January 2018

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Requirements for CD1d recognition by human invariant Valpha24+ CD4-CD8- T cells

21 January 2018

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Phenotypic and functional analysis of CD4+ NKRP1A+ human T lymphocytes. Direct evidence that the NKRP1A molecule is involved in transendothelial migration

21 January 2018

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CD161 (NKR-P1A) costimulation of CD1d-dependent activation of human T cells expressing invariant V alpha 24 J alpha Q T cell receptor alpha chains

21 January 2018

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CD8(+)NKR-P1A (+)T cells preferentially accumulate in human liver

21 January 2018

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Selective reduction of T cells bearing invariant V alpha 24J alpha Q antigen receptor in patients with systemic sclerosis

21 January 2018

1 reference

Insulin-IGF2 region on chromosome 11p encodes a gene implicated in HLA-DR4-dependent diabetes susceptibility

21 January 2018

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The CTLA-4 gene region of chromosome 2q33 is linked to, and associated with, type 1 diabetes. Belgian Diabetes Registry

21 January 2018

2 references

21 January 2018

inferred from DOI database lookup

7 January 2021

based on heuristic

Susceptibility to human type 1 diabetes at IDDM2 is determined by tandem repeat variation at the insulin gene minisatellite locus

1 reference

Incidence of childhood-onset Type 1 diabetes mellitus in Devon and Cornwall, England, 1975-1996

21 January 2018

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Number of autoantibodies (against insulin, GAD or ICA512/IA2) rather than particular autoantibody specificities determines risk of type I diabetes

21 January 2018

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Prediction of type I diabetes in first-degree relatives using a combination of insulin, GAD, and ICA512bdc/IA-2 autoantibodies

21 January 2018

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Sometimes it's hot, sometimes it's not

21 January 2018

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Genetic susceptibility factors in type 1 diabetes: linkage, disequilibrium and functional analyses

21 January 2018

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A Polymorphic Locus Near the Human Insulin Gene Is Associated with Insulin-dependent Diabetes Melliitus

21 January 2018

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Fine-mapping of the type 1 diabetes locus (IDDM4) on chromosome 11q and evaluation of two candidate genes (FADD and GALN) by affected sibpair and linkage-disequilibrium analyses

21 January 2018

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Saturation multipoint linkage mapping of chromosome 6q in type 1 diabetes

21 January 2018

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Insulin-dependent diabetes mellitus (IDDM) is associated with CTLA4 polymorphisms in multiple ethnic groups

21 January 2018

1 reference

Genetic and physical mapping of a type 1 diabetes susceptibility gene (IDDM12) to a 100-kb phagemid artificial chromosome clone containing D2S72-CTLA4-D2S105 on chromosome 2q33

21 January 2018

1 reference

Modelling the effects of genetic and environmental factors on the risk of autoimmune disease

21 January 2018

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NK1.1+ CD4+ CD8- thymocytes with specific lymphokine secretion

21 January 2018

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Requirement of IL-7 for IL-4-producing potential of MHC class I-selected CD4-CD8-TCR alpha beta+ thymocytes

21 January 2018

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NK T cell-derived IL-10 is essential for the differentiation of antigen-specific T regulatory cells in systemic tolerance

21 January 2018

1 reference

Liver-associated lymphocytes expressing NK1.1 are essential for oral immune tolerance induction in a murine model

21 January 2018

1 reference

Early quantitative and functional deficiency of NK1+-like thymocytes in the NOD mouse

21 January 2018

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Association between alphabetaTCR+CD4-CD8- T-cell deficiency and IDDM in NOD/Lt mice

21 January 2018

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Diabetes prone BB rats are severely deficient in natural killer T cells

21 January 2018

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Dendritic cells are targets for human invariant Valpha24+ natural killer T-cell cytotoxic activity: an important immune regulatory function

21 January 2018

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CD1d-Restricted NKT Cells: An Interstrain Comparison

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/DMRR.238

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2 August 2017

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