pH-sensitivity of the ribosomal peptidyl transfer reaction dependent on the identity of the A-site aminoacyl-tRNA. (Q34471932)

2 August 2017

title

pH-sensitivity of the ribosomal peptidyl transfer reaction dependent on the identity of the A-site aminoacyl-tRNA. (English)

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2 August 2017

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7

Måns Ehrenberg

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2 August 2017

1

Magnus Johansson

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2 August 2017

5

Johan Åqvist

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2 August 2017

Ka-Weng Ieong

2

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2 August 2017

Stefan Trobro

series ordinal

3

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2 August 2017

Peter Strazewski

series ordinal

4

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2 August 2017

Michael Y Pavlov

series ordinal

6

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2 August 2017

language of work or name

English

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publication date

17 December 2010

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Proceedings of the National Academy of Sciences of the United States of America

2 August 2017

published in

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2 August 2017

volume

108

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2 August 2017

issue

1

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2 August 2017

page(s)

79-84

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Optimization of speed and accuracy of decoding in translation

2 August 2017

cites work

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3017169

Chemical models of peptide formation in translation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3017169

The Crystal Structure of the Ribosome Bound to EF-Tu and Aminoacyl-tRNA

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3017169

Fidelity at the molecular level: lessons from protein synthesis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3017169

Slow peptide bond formation by proline and other N-alkylamino acids in translation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3017169

Different aa-tRNAs are selected uniformly on the ribosome

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3017169

The kinetics of ribosomal peptidyl transfer revisited

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3017169

Specificity of translation for N-alkyl amino acids

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3017169

Importance of tRNA interactions with 23S rRNA for peptide bond formation on the ribosome: studies with substrate analogs

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3017169

The ribosomal peptidyl transferase

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3017169

The interaction between C75 of tRNA and the A loop of the ribosome stimulates peptidyl transferase activity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3017169

An induced-fit mechanism to promote peptide bond formation and exclude hydrolysis of peptidyl-tRNA.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3017169

Mechanism of peptide bond synthesis on the ribosome

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3017169

Mononucleotide derivatives as ribosomal P-site substrates reveal an important contribution of the 2'-OH to activity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3017169

The path to perdition is paved with protons

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3017169

Structural insights into peptide bond formation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3017169

The structural basis of ribosome activity in peptide bond synthesis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3017169

Complete kinetic mechanism of elongation factor Tu-dependent binding of aminoacyl-tRNA to the A site of the E. coli ribosome

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3017169

Fast recycling of Escherichia coli ribosomes requires both ribosome recycling factor (RRF) and release factor RF3

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3017169

Kinetic properties of Escherichia coli ribosomes with altered forms of S12

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3017169

Nucleoside triphosphate regeneration decreases the frequency of translation errors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3017169

The Peptidyltransferase Center of Ribosomes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3017169

Substrate-assisted catalysis of peptide bond formation by the ribosome

6 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1012612107

Structural insights into the roles of water and the 2' hydroxyl of the P site tRNA in the peptidyl transferase reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1012612107

The role of 23S ribosomal RNA residue A2451 in peptide bond synthesis revealed by atomic mutagenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1012612107

Transient conformational states of aminoacyl-tRNA during ribosome binding catalyzed by elongation factor Tu.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1012612107

Important contribution to catalysis of peptide bond formation by a single ionizing group within the ribosome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1012612107

Uncovering the enzymatic pKa of the ribosomal peptidyl transferase reaction utilizing a fluorinated puromycin derivative

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1012612107

Q: a molecular dynamics program for free energy calculations and empirical valence bond simulations in biomolecular systems.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1012612107

2'/3'-O-peptidyl adenosine as a general base catalyst of its own external peptidyl transfer: implications for the ribosome catalytic mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1012612107

A new method for predicting binding affinity in computer-aided drug design

21 January 2018

1 reference

12 December 2020

THE MECHANISM OF HYDROLYSIS OF AMINO ACYL RNA

1 reference

12 December 2020

Peptide bond formation does not involve acid-base catalysis by ribosomal residues

1 reference

12 December 2020

Analysis of predictions for the catalytic mechanism of ribosomal peptidyl transfer

1 reference

12 December 2020

Combining docking, molecular dynamics and the linear interaction energy method to predict binding modes and affinities for non-nucleoside inhibitors to HIV-1 reverse transcriptase

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1012612107

1 reference

2 August 2017

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2 August 2017

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