Saturated, but not n-6 polyunsaturated, fatty acids induce insulin resistance: role of intramuscular accumulation of lipid metabolites (Q34476883)

2 August 2017

Saturated, but not n-6 polyunsaturated, fatty acids induce insulin resistance: role of intramuscular accumulation of lipid metabolites (English)

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2 August 2017

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Jong Sam Lee

1

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2 August 2017

Srijan K Pinnamaneni

2

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2 August 2017

Su Ju Eo

3

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2 August 2017

In Ho Cho

4

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2 August 2017

Jae Hwan Pyo

5

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2 August 2017

Chang Keun Kim

6

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2 August 2017

Andrew J Sinclair

7

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2 August 2017

Mark A Febbraio

8

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2 August 2017

Matthew J Watt

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2 August 2017

language of work or name

English

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publication date

15 December 2005

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Journal of Applied Physiology

2 August 2017

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2 August 2017

100

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2 August 2017

1467-1474

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2 August 2017

5

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Ceramide content is increased in skeletal muscle from obese insulin-resistant humans

2 August 2017

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https://api.crossref.org/works/10.1152%2FJAPPLPHYSIOL.01438.2005

Effects of intravenous and dietary lipid challenge on intramyocellular lipid content and the relation with insulin sensitivity in humans

21 January 2018

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https://api.crossref.org/works/10.1152%2FJAPPLPHYSIOL.01438.2005

Effects of acute changes of plasma free fatty acids on intramyocellular fat content and insulin resistance in healthy subjects

21 January 2018

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https://api.crossref.org/works/10.1152%2FJAPPLPHYSIOL.01438.2005

Disassociation of muscle triglyceride content and insulin sensitivity after exercise training in patients with Type 2 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FJAPPLPHYSIOL.01438.2005

A role for protein phosphatase 2A-like activity, but not atypical protein kinase Czeta, in the inhibition of protein kinase B/Akt and glycogen synthesis by palmitate

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FJAPPLPHYSIOL.01438.2005

A role for ceramide, but not diacylglycerol, in the antagonism of insulin signal transduction by saturated fatty acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FJAPPLPHYSIOL.01438.2005

Characterizing the effects of saturated fatty acids on insulin signaling and ceramide and diacylglycerol accumulation in 3T3-L1 adipocytes and C2C12 myotubes

21 January 2018

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https://api.crossref.org/works/10.1152%2FJAPPLPHYSIOL.01438.2005

The multi-dimensional regulation of gene expression by fatty acids: polyunsaturated fats as nutrient sensors

21 January 2018

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https://api.crossref.org/works/10.1152%2FJAPPLPHYSIOL.01438.2005

Role for stearoyl-CoA desaturase-1 in leptin-mediated weight loss

21 January 2018

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https://api.crossref.org/works/10.1152%2FJAPPLPHYSIOL.01438.2005

Relation of triglyceride stores in skeletal muscle cells to central obesity and insulin sensitivity in European and South Asian men.

21 January 2018

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https://api.crossref.org/works/10.1152%2FJAPPLPHYSIOL.01438.2005

Differential utilization of saturated palmitate and unsaturated oleate: evidence from cultured myotubes

21 January 2018

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https://api.crossref.org/works/10.1152%2FJAPPLPHYSIOL.01438.2005

Skeletal muscle lipid content and insulin resistance: evidence for a paradox in endurance-trained athletes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FJAPPLPHYSIOL.01438.2005

Effect of streptozotocin-diabetes on the functioning of the sphingomyelin-signalling pathway in skeletal muscles of the rat.

21 January 2018

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https://api.crossref.org/works/10.1152%2FJAPPLPHYSIOL.01438.2005

Training affects muscle phospholipid fatty acid composition in humans

21 January 2018

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https://api.crossref.org/works/10.1152%2FJAPPLPHYSIOL.01438.2005

Lipid-induced insulin resistance in human muscle is associated with changes in diacylglycerol, protein kinase C, and IkappaB-alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FJAPPLPHYSIOL.01438.2005

Differential effects of safflower oil versus fish oil feeding on insulin-stimulated glycogen synthesis, glycolysis, and pyruvate dehydrogenase flux in skeletal muscle: a 13C nuclear magnetic resonance study.

21 January 2018

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https://api.crossref.org/works/10.1152%2FJAPPLPHYSIOL.01438.2005

Intramyocellular lipid concentrations are correlated with insulin sensitivity in humans: a 1H NMR spectroscopy study.

21 January 2018

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https://api.crossref.org/works/10.1152%2FJAPPLPHYSIOL.01438.2005

Rosiglitazone enhances glucose tolerance by mechanisms other than reduction of fatty acid accumulation within skeletal muscle

21 January 2018

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https://api.crossref.org/works/10.1152%2FJAPPLPHYSIOL.01438.2005

Differential oxidation of saturated and unsaturated fatty acids in vivo in the rat.

21 January 2018

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https://api.crossref.org/works/10.1152%2FJAPPLPHYSIOL.01438.2005

Triglyceride accumulation protects against fatty acid-induced lipotoxicity

21 January 2018

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https://api.crossref.org/works/10.1152%2FJAPPLPHYSIOL.01438.2005

Saturated fat intake and insulin resistance in men with coronary artery disease. The Stanford Coronary Risk Intervention Project Investigators and Staff.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FJAPPLPHYSIOL.01438.2005

Fiber type- and fatty acid composition-dependent effects of high-fat diets on rat muscle triacylglyceride and fatty acid transporter protein-1 content

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FJAPPLPHYSIOL.01438.2005

Improved insulin sensitivity by bezafibrate in rats: relationship to fatty acid composition of skeletal-muscle triglycerides

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FJAPPLPHYSIOL.01438.2005

DAG accumulation from saturated fatty acids desensitizes insulin stimulation of glucose uptake in muscle cells

21 January 2018

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https://api.crossref.org/works/10.1152%2FJAPPLPHYSIOL.01438.2005

Loss of stearoyl-CoA desaturase-1 function protects mice against adiposity

21 January 2018

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https://api.crossref.org/works/10.1152%2FJAPPLPHYSIOL.01438.2005

Skeletal muscle triglyceride levels are inversely related to insulin action.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FJAPPLPHYSIOL.01438.2005

Tissue and isoform-selective activation of protein kinase C in insulin-resistant obese Zucker rats - effects of feeding.

21 January 2018

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https://api.crossref.org/works/10.1152%2FJAPPLPHYSIOL.01438.2005

Dietary fat, insulin sensitivity and the metabolic syndrome.

21 January 2018

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https://api.crossref.org/works/10.1152%2FJAPPLPHYSIOL.01438.2005

Polyunsaturated fatty acid regulation of genes of lipid metabolism

21 January 2018

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https://api.crossref.org/works/10.1152%2FJAPPLPHYSIOL.01438.2005

Ceramide generation is sufficient to account for the inhibition of the insulin-stimulated PKB pathway in C2C12 skeletal muscle cells pretreated with palmitate

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FJAPPLPHYSIOL.01438.2005

Influence of dietary fat composition on development of insulin resistance in rats. Relationship to muscle triglyceride and omega-3 fatty acids in muscle phospholipid

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FJAPPLPHYSIOL.01438.2005

Relationship between insulin sensitivity and sphingomyelin signaling pathway in human skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FJAPPLPHYSIOL.01438.2005

Regulation of insulin action by ceramide: dual mechanisms linking ceramide accumulation to the inhibition of Akt/protein kinase B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FJAPPLPHYSIOL.01438.2005

A role for sphingolipids in producing the common features of type 2 diabetes, metabolic syndrome X, and Cushing's syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FJAPPLPHYSIOL.01438.2005

Polyunsaturated fatty acids inhibit hepatic stearoyl-CoA desaturase-1 gene in diabetic mice

21 January 2018

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https://api.crossref.org/works/10.1152%2FJAPPLPHYSIOL.01438.2005

Intramuscular triacylglycerol, glycogen and acetyl group metabolism during 4 h of moderate exercise in man

21 January 2018

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https://api.crossref.org/works/10.1152%2FJAPPLPHYSIOL.01438.2005

Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FJAPPLPHYSIOL.01438.2005

10.1152/JAPPLPHYSIOL.01438.2005

21 January 2018

Identifiers

DOI

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2 August 2017

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