Catalytic in vivo protein knockdown by small-molecule PROTACs. (Q34480735)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26075522%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

title

Catalytic in vivo protein knockdown by small-molecule PROTACs (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26075522%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

5

1 reference

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17 February 2020

Giovanna Bergamini

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26075522%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Linda N Casillas

21

1 reference

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17 February 2020

Craig M. Crews

29

1 reference

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17 February 2020

author name string

Daniel P Bondeson

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26075522%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Alina Mares

2

1 reference

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17 February 2020

Ian E D Smith

3

1 reference

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17 February 2020

Eunhwa Ko

4

1 reference

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17 February 2020

Afjal H Miah

6

1 reference

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17 February 2020

Katie E Mulholland

7

1 reference

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17 February 2020

Natasha Routly

8

1 reference

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17 February 2020

Dennis L Buckley

9

1 reference

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17 February 2020

Jeffrey L Gustafson

10

1 reference

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17 February 2020

Nico Zinn

11

1 reference

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17 February 2020

Satoko Shimamura

13

1 reference

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17 February 2020

Maria Faelth-Savitski

15

1 reference

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17 February 2020

Marcus Bantscheff

16

1 reference

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17 February 2020

Carly Cox

17

1 reference

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17 February 2020

Deborah A Gordon

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26075522%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Ryan R Willard

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26075522%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

John J Flanagan

20

1 reference

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17 February 2020

Bartholomew J Votta

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26075522%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Willem den Besten

23

1 reference

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17 February 2020

Kristoffer Famm

24

1 reference

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17 February 2020

Laurens Kruidenier

25

1 reference

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17 February 2020

Paul S Carter

26

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26075522%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

John D Harling

27

1 reference

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17 February 2020

Ian Churcher

28

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26075522%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Paola Grandi

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26075522%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

publication date

10 June 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26075522%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

number of pages

7

1 reference

inferred from page(s)

published in

Nature Chemical Biology

1 reference

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17 February 2020

volume

11

1 reference

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17 February 2020

issue

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26075522%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

page(s)

611-617

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26075522%20AND%20SRC:MED&resulttype=core&format=json

RIP kinases: key decision makers in cell death and innate immunity

17 February 2020

cites work

1 reference

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Small-molecule control of intracellular protein levels through modulation of the ubiquitin proteasome system

6 July 2018

1 reference

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Development of hybrid small molecules that induce degradation of estrogen receptor-alpha and necrotic cell death in breast cancer cells.

6 July 2018

1 reference

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Posttranslational protein knockdown coupled to receptor tyrosine kinase activation with phosphoPROTACs

6 July 2018

1 reference

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A comprehensive mathematical model for three-body binding equilibria

6 July 2018

1 reference

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Small-Molecule Inhibitors of the Interaction between the E3 Ligase VHL and HIF1α

6 July 2018

1 reference

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A HaloTag-based small molecule microarray screening methodology with increased sensitivity and multiplex capabilities

6 July 2018

1 reference

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Double protein knockdown of cIAP1 and CRABP-II using a hybrid molecule consisting of ATRA and IAPs antagonist.

6 July 2018

1 reference

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A selective inhibitor reveals PI3Kγ dependence of T(H)17 cell differentiation

6 July 2018

1 reference

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Targeting the von Hippel–Lindau E3 Ubiquitin Ligase Using Small Molecules To Disrupt the VHL/HIF-1α Interaction

6 July 2018

1 reference

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Global quantification of mammalian gene expression control

6 July 2018

1 reference

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6 July 2018

1 reference

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Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes

6 July 2018

1 reference

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Identification of diaryl ether-based ligands for estrogen-related receptor α as potential antidiabetic agents

6 July 2018

1 reference

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Chemoproteomics-based kinome profiling and target deconvolution of clinical multi-kinase inhibitors in primary chronic lymphocytic leukemia cells.

6 July 2018

1 reference

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Potent and selective photo-inactivation of proteins with peptoid-ruthenium conjugates

6 July 2018

1 reference

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Targeted data acquisition for improved reproducibility and robustness of proteomic mass spectrometry assays

6 July 2018

1 reference

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siRNA applications in nanomedicine

6 July 2018

1 reference

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Design, synthesis and selection of DNA-encoded small-molecule libraries

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4629852

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4629852

Targeting steroid hormone receptors for ubiquitination and degradation in breast and prostate cancer

6 July 2018

1 reference

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Targeted intracellular protein degradation induced by a small molecule: En route to chemical proteomics

6 July 2018

1 reference

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Small molecules destabilize cIAP1 by activating auto-ubiquitylation

6 July 2018

1 reference

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Quantitative chemical proteomics reveals mechanisms of action of clinical ABL kinase inhibitors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4629852

Potentiation of ICI182,780 (Fulvestrant)-induced estrogen receptor-alpha degradation by the estrogen receptor-related receptor-alpha inverse agonist XCT790.

6 July 2018

1 reference

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Molecular mechanisms involved in the regulation of cytokine production by muramyl dipeptide

6 July 2018

1 reference

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RNAi therapeutics: a potential new class of pharmaceutical drugs

6 July 2018

1 reference

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A robust small-molecule microarray platform for screening cell lysates

6 July 2018

1 reference

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Absolute quantification of proteins by LCMSE: a virtue of parallel MS acquisition

6 July 2018

1 reference

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Chemical genetic control of protein levels: selective in vivo targeted degradation

6 July 2018

1 reference

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Structural basis for the recognition of hydroxyproline in HIF-1 alpha by pVHL

6 July 2018

1 reference

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Structure of an HIF-1alpha -pVHL complex: hydroxyproline recognition in signaling

6 July 2018

1 reference

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Controlling the false discovery rate in behavior genetics research

6 July 2018

1 reference

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CARD15 mutations in Blau syndrome

6 July 2018

1 reference

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Protacs: chimeric molecules that target proteins to the Skp1-Cullin-F box complex for ubiquitination and degradation

6 July 2018

1 reference

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Induction of HIF-1alpha in response to hypoxia is instantaneous

6 July 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4629852

6 July 2018

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1858

7 January 2021

inferred from DOI database lookup

Activation of HIF1alpha ubiquitination by a reconstituted von Hippel-Lindau (VHL) tumor suppressor complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4629852

Identification of the von Hippel-lindau tumor-suppressor protein as part of an active E3 ubiquitin ligase complex

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4629852

Epoxomicin, a potent and selective proteasome inhibitor, exhibits in vivo antiinflammatory activity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4629852

Chemoproteomics reveals time-dependent binding of histone deacetylase inhibitors to endogenous repressor complexes.

6 July 2018

1 reference

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Structural basis for hijacking CBF-β and CUL5 E3 ligase complex by HIV-1 Vif.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4629852

Measuring and managing ratio compression for accurate iTRAQ/TMT quantification.

27 October 2018

1 reference

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A call to ARMs: the promise of immunomodulatory small molecules

27 October 2018

1 reference

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High-resolution enabled TMT 8-plexing.

27 October 2018

1 reference

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Implementation and evaluation of relative and absolute quantification in shotgun proteomics with label-free methods

27 October 2018

1 reference

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Proteomics strategy for quantitative protein interaction profiling in cell extracts.

27 October 2018

1 reference

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Development of an aryl hydrocarbon receptor antagonist using the proteolysis-targeting chimeric molecules approach: a potential tool for chemoprevention

27 October 2018

1 reference

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Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs

27 October 2018

1 reference

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Delayed fragmentation and optimized isolation width settings for improvement of protein identification and accuracy of isobaric mass tag quantification on Orbitrap-type mass spectrometers

27 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26075522

12 December 2020

inferred from PubMed ID database lookup

Early-onset sarcoidosis and CARD15 mutations with constitutive nuclear factor-kappaB activation: common genetic etiology with Blau syndrome

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26075522

12 December 2020

inferred from PubMed ID database lookup

What is the right dose? The elusive optimal biologic dose in phase I clinical trials

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26075522

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/NCHEMBIO.1858

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26075522%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26075522%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

PubMed publication ID

26075522

1 reference