Ageing induced vascular smooth muscle cell senescence in atherosclerosis (Q34485057)

A complex secretory program orchestrated by the inflammasome controls paracrine senescence

21 January 2018

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Chemokine signaling via the CXCR2 receptor reinforces senescence

21 January 2018

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Akt regulates the survival of vascular smooth muscle cells via inhibition of FoxO3a and GSK3.

21 January 2018

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21 January 2018

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Mitochondrial integrity and function in atherogenesis

21 January 2018

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Apoptosis of human vascular smooth muscle cells derived from normal vessels and coronary atherosclerotic plaques

21 January 2018

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Smooth muscle cells in atherosclerosis originate from the local vessel wall and not circulating progenitor cells in ApoE knockout mice.

21 January 2018

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Effects of aging and hypoxia-inducible factor-1 activity on angiogenic cell mobilization and recovery of perfusion after limb ischemia

21 January 2018

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Detection of mtDNA with 4977 bp deletion in blood cells and atherosclerotic lesions of patients with coronary artery disease.

21 January 2018

1 reference

Telomere length, risk of coronary heart disease, and statin treatment in the West of Scotland Primary Prevention Study: a nested case-control study

21 January 2018

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Leukocyte telomere length is associated with high-risk plaques on virtual histology intravascular ultrasound and increased proinflammatory activity.

21 January 2018

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Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors

21 January 2018

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Epigenetic basis for the transcriptional hyporesponsiveness of the human inducible nitric oxide synthase gene in vascular endothelial cells.

21 January 2018

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Telomere length and replicative aging in human vascular tissues

21 January 2018

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Age decreases endothelial progenitor cell recruitment through decreases in hypoxia-inducible factor 1alpha stabilization during ischemia

21 January 2018

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A DNA damage checkpoint response in telomere-initiated senescence

21 January 2018

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Senescent cells as a source of inflammatory factors for tumor progression

21 January 2018

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Vascular endothelial dysfunction with aging: endothelin-1 and endothelial nitric oxide synthase

21 January 2018

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Protection of vascular cells from oxidative stress by proteasome inhibition depends on Nrf2.

21 January 2018

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Loss of Akt1 leads to severe atherosclerosis and occlusive coronary artery disease

21 January 2018

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Absence of Akt1 reduces vascular smooth muscle cell migration and survival and induces features of plaque vulnerability and cardiac dysfunction during atherosclerosis.

21 January 2018

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The roles of senescence and telomere shortening in cardiovascular disease

21 January 2018

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Vascular smooth muscle cell sirtuin 1 protects against DNA damage and inhibits atherosclerosis

21 January 2018

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Effects of DNA damage in smooth muscle cells in atherosclerosis.

21 January 2018

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Mammalian telomeres end in a large duplex loop

21 January 2018

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Circulating endothelial progenitor cells do not contribute to regeneration of endothelium after murine arterial injury.

21 January 2018

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Circulating endothelial progenitor cells do not contribute to plaque endothelium in murine atherosclerosis.

21 January 2018

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Impaired progenitor cell activity in age-related endothelial dysfunction

21 January 2018

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Angiotensin II-mediated oxidative DNA damage accelerates cellular senescence in cultured human vascular smooth muscle cells via telomere-dependent and independent pathways.

21 January 2018

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Abundant progenitor cells in the adventitia contribute to atherosclerosis of vein grafts in ApoE-deficient mice

21 January 2018

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p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2

21 January 2018

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Potential involvement of LOX-1 in functional consequences of endothelial senescence

21 January 2018

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Local hypomethylation in atherosclerosis found in rabbit ec-sod gene.

21 January 2018

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Nox NADPH oxidases and the endoplasmic reticulum

21 January 2018

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21 January 2018

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21 January 2018

The hallmarks of aging

1 reference

DNA methylation polymorphisms precede any histological sign of atherosclerosis in mice lacking apolipoprotein E.

21 January 2018

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Statins use a novel Nijmegen breakage syndrome-1-dependent pathway to accelerate DNA repair in vascular smooth muscle cells

21 January 2018

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Oxidative DNA damage and repair in experimental atherosclerosis are reversed by dietary lipid lowering

21 January 2018

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Elevated levels of oxidative DNA damage and DNA repair enzymes in human atherosclerotic plaques

21 January 2018

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Vascular smooth muscle cells undergo telomere-based senescence in human atherosclerosis: effects of telomerase and oxidative stress.

21 January 2018

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Endothelial cell senescence in human atherosclerosis: role of telomere in endothelial dysfunction

21 January 2018

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The Sirt1 activator SRT3025 provides atheroprotection in Apoe-/- mice by reducing hepatic Pcsk9 secretion and enhancing Ldlr expression

21 January 2018

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Differential cyclin E expression in human in-stent stenosis smooth muscle cells identifies targets for selective anti-restenosis therapy.

21 January 2018

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Leukocyte telomere length is associated with measures of subclinical atherosclerosis

21 January 2018

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Feedback between p21 and reactive oxygen production is necessary for cell senescence

21 January 2018

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Defect in insulin-like growth factor-1 survival mechanism in atherosclerotic plaque-derived vascular smooth muscle cells is mediated by reduced surface binding and signaling

21 January 2018

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An activator of mTOR inhibits oxLDL-induced autophagy and apoptosis in vascular endothelial cells and restricts atherosclerosis in apolipoprotein E⁻/⁻ mice

21 January 2018

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Chromosomal damage and atherosclerosis. A protective effect from simvastatin

21 January 2018

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DNA hypomethylation in the origin and pathogenesis of human diseases

21 January 2018

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Vascular wall progenitor cells in health and disease

21 January 2018

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Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion.

21 January 2018

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Reduction of nitric oxide producing activity associated with in vitro aging in cultured human umbilical vein endothelial cell

21 January 2018

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21 January 2018

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Mechanisms of ER stress-induced apoptosis in atherosclerosis

21 January 2018

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Defective CXCR4 expression in aged bone marrow cells impairs vascular regeneration

21 January 2018

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Aging enhances the basal production of IL-6 and CCL2 in vascular smooth muscle cells

21 January 2018

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Statins enhance migratory capacity by upregulation of the telomere repeat-binding factor TRF2 in endothelial progenitor cells.

21 January 2018

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Differentiation of multipotent vascular stem cells contributes to vascular diseases

21 January 2018

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Contribution of stem cells to neointimal formation of decellularized vessel grafts in a novel mouse model.

21 January 2018

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Akt1 regulates vascular smooth muscle cell apoptosis through FoxO3a and Apaf1 and protects against arterial remodeling and atherosclerosis

21 January 2018

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The role of senescent cells in ageing

21 January 2018

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TRF2 Protects Human Telomeres from End-to-End Fusions

21 January 2018

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Integrated analysis of microarray data of atherosclerotic plaques: modulation of the ubiquitin-proteasome system

21 January 2018

1 reference

Attenuation of early atherogenesis in low-density lipoprotein receptor-deficient mice by proteasome inhibition.

21 January 2018

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Cellular aging reflected by leukocyte telomere length predicts advanced atherosclerosis and cardiovascular disease risk.

21 January 2018

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Pot1 deficiency initiates DNA damage checkpoint activation and aberrant homologous recombination at telomeres

21 January 2018

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Nox4-derived H2O2 mediates endoplasmic reticulum signaling through local Ras activation

21 January 2018

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Peroxisome proliferator-activated receptor γ coactivator-1α is a central negative regulator of vascular senescence

21 January 2018

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Impaired CXCR4 expression and cell engraftment of bone marrow-derived cells from aged atherogenic mice

21 January 2018

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Mitochondrial DNA damage can promote atherosclerosis independently of reactive oxygen species through effects on smooth muscle cells and monocytes and correlates with higher-risk plaques in humans.

21 January 2018

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Premature senescence of highly proliferative endothelial progenitor cells is induced by tumor necrosis factor-alpha via the p38 mitogen-activated protein kinase pathway

21 January 2018

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Stress-induced premature senescence. Essence of life, evolution, stress, and aging

21 January 2018

1 reference

PubMed Central

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4933105

Telomere length in vascular tissues from patients with atherosclerotic disease

27 October 2018

1 reference

Carbamylated low-density lipoprotein induces oxidative stress and accelerated senescence in human endothelial progenitor cells

21 January 2018

1 reference

12 December 2020

Cooperative interactions between RB and p53 regulate cell proliferation, cell senescence, and apoptosis in human vascular smooth muscle cells from atherosclerotic plaques

1 reference

12 December 2020

Proliferation in primary and restenotic coronary atherectomy tissue. Implications for antiproliferative therapy

1 reference

12 December 2020

White cell telomere length and risk of premature myocardial infarction

1 reference

12 December 2020

Telomere shortening in human coronary artery diseases

1 reference

12 December 2020

Evidence for DNA damage in patients with coronary artery disease

1 reference

12 December 2020