Nimbolide sensitizes human colon cancer cells to TRAIL through reactive oxygen species- and ERK-dependent up-regulation of death receptors, p53, and Bax. (Q34488880)

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English	Nimbolide sensitizes human colon cancer cells to TRAIL through reactive oxygen species- and ERK-dependent up-regulation of death receptors, p53, and Bax.	scientific article

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scholarly article

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16 January 2020

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Dataset for "Continued use of retracted papers: Temporal trends in citations and (lack of) awareness of retractions shown in citation contexts in biomedicine"

Continued use of retracted papers: Temporal trends in citations and (lack of) awareness of retractions shown in citation contexts in biomedicine

Nimbolide sensitizes human colon cancer cells to TRAIL through reactive oxygen species- and ERK-dependent up-regulation of death receptors, p53, and Bax (English)

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16 January 2020

reactive oxygen species

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based on heuristic

inferred from title

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Kanokkarn Phromnoi

3

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16 January 2020

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Subash C Gupta

1

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16 January 2020

Simone Reuter

2

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16 January 2020

Byoungduck Park

4

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16 January 2020

Padmanabhan S Hema

5

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16 January 2020

Mangalam Nair

6

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16 January 2020

Bharat B Aggarwal

7

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16 January 2020

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15 November 2010

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16 January 2020

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13

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Journal of Biological Chemistry

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16 January 2020

286

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16 January 2020

2

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16 January 2020

1134-1146

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16 January 2020

Modification of Cysteine 179 of IκBα Kinase by Nimbolide Leads to Down-regulation of NF-κB-regulated Cell Survival and Proliferative Proteins and Sensitization of Tumor Cells to Chemotherapeutic Agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020720

6 July 2018

Butein sensitizes human hepatoma cells to TRAIL-induced apoptosis via extracellular signal-regulated kinase/Sp1-dependent DR5 upregulation and NF-kappaB inactivation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020720

6 July 2018

Celastrol, a triterpene, enhances TRAIL-induced apoptosis through the down-regulation of cell survival proteins and up-regulation of death receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020720

6 July 2018

Zerumbone enhances TRAIL-induced apoptosis through the induction of death receptors in human colon cancer cells: Evidence for an essential role of reactive oxygen species.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020720

6 July 2018

High sensitivity of ovarian cancer cells to the synthetic triterpenoid CDDO-Imidazolide.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020720

6 July 2018

TRAIL agonists on clinical trials for cancer therapy: the promises and the challenges

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020720

6 July 2018

Baicalein overcomes tumor necrosis factor-related apoptosis-inducing ligand resistance via two different cell-specific pathways in cancer cells but not in normal cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020720

6 July 2018

Nimbolide a limonoid from Azadirachta indica inhibits proliferation and induces apoptosis of human choriocarcinoma (BeWo) cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020720

6 July 2018

A mitochondrial block and expression of XIAP lead to resistance to TRAIL-induced apoptosis during progression to metastasis of a colon carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020720

6 July 2018

Death-receptor O-glycosylation controls tumor-cell sensitivity to the proapoptotic ligand Apo2L/TRAIL.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020720

6 July 2018

Antiproliferative effect on human cancer cell lines after treatment with nimbolide extracted from an edible part of the neem tree (Azadirachta indica).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020720

6 July 2018

Dual role of hydrogen peroxide in cancer: possible relevance to cancer chemoprevention and therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020720

6 July 2018

Celastrol, a novel triterpene, potentiates TNF-induced apoptosis and suppresses invasion of tumor cells by inhibiting NF-kappaB-regulated gene products and TAK1-mediated NF-kappaB activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020720

6 July 2018

Synthesis and biological activity of amide derivatives of nimbolide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020720

6 July 2018

Protein farnesyltransferase inhibitor (SCH 66336) abolishes NF-kappaB activation induced by various carcinogens and inflammatory stimuli leading to suppression of NF-kappaB-regulated gene expression and up-regulation of apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020720

6 July 2018

Signalling pathways of the TNF superfamily: a double-edged sword

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020720

6 July 2018

Redox signaling and the MAP kinase pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020720

6 July 2018

Natural products as sources of new drugs over the period 1981-2002.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020720

6 July 2018

Death receptors leave a caspase footprint that Smacs of XIAP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020720

6 July 2018

The Hallmarks of Cancer

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020720

6 July 2018

KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020720

6 July 2018

An antagonist decoy receptor and a death domain-containing receptor for TRAIL

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020720

6 July 2018

X-linked IAP is a direct inhibitor of cell-death proteases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020720

6 July 2018

The receptor for the cytotoxic ligand TRAIL

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020720

6 July 2018

Apo-3, a new member of the tumor necrosis factor receptor family, contains a death domain and activates apoptosis and NF-kappa B

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020720

6 July 2018

Identification and characterization of a new member of the TNF family that induces apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020720

6 July 2018

Nimbolide, a constituent of Azadirachta indica, inhibits Plasmodium falciparum in culture

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020720

6 July 2018

Mechanisms of resistance to TRAIL-induced apoptosis in primary B cell chronic lymphocytic leukaemia.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.191379

21 January 2018

Downregulation of Bcl-2, FLIP or IAPs (XIAP and survivin) by siRNAs sensitizes resistant melanoma cells to Apo2L/TRAIL-induced apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.191379

21 January 2018

The neem limonoids azadirachtin and nimbolide inhibit hamster cheek pouch carcinogenesis by modulating xenobiotic-metabolizing enzymes, DNA damage, antioxidants, invasion and angiogenesis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.191379

21 January 2018

Curcumin (diferuloylmethane) down-regulates the constitutive activation of nuclear factor-kappa B and IkappaBalpha kinase in human multiple myeloma cells, leading to suppression of proliferation and induction of apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.191379

21 January 2018

LY303511 enhances TRAIL sensitivity of SHEP-1 neuroblastoma cells via hydrogen peroxide-mediated mitogen-activated protein kinase activation and up-regulation of death receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.191379

21 January 2018

Tumor-cell resistance to death receptor--induced apoptosis through mutational inactivation of the proapoptotic Bcl-2 homolog Bax.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.191379

21 January 2018

Questionable methods of cancer management: hydrogen peroxide and other 'hyperoxygenation' therapies

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.191379

21 January 2018

A Method of destroying a Malignant Rat Tumour in vivo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.191379

21 January 2018

Hydrogen Peroxide and Cancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.191379

21 January 2018

Regulation of death receptor expression and TRAIL/Apo2L-induced apoptosis by NF-kappaB

1 reference

https://pubmed.ncbi.nlm.nih.gov/21078664

12 December 2020

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inferred from PubMed ID database lookup

Bcl-XL protects pancreatic adenocarcinoma cells against CD95- and TRAIL-receptor-mediated apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21078664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nimbolide and isonimbolide

1 reference

https://pubmed.ncbi.nlm.nih.gov/21078664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hydrogen peroxide enhances TRAIL-induced cell death through up-regulation of DR5 in human astrocytic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21078664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sodium nitroprusside enhances TRAIL-induced apoptosis via a mitochondria-dependent pathway in human colorectal carcinoma CX-1 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21078664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ethacrynic acid butyl-ester induces apoptosis in leukemia cells through a hydrogen peroxide mediated pathway independent of glutathione S-transferase P1-1 inhibition

1 reference

https://pubmed.ncbi.nlm.nih.gov/21078664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mcl-1 interacts with truncated Bid and inhibits its induction of cytochrome c release and its role in receptor-mediated apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21078664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/21078664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Optimised isolation procedure for biologically active compounds nimbolide and 28-deoxonimbolide from Azadirachta indica leaves

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.1074/JBC.M110.191379

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10.1074/JBC.M110.191379

1 reference

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16 January 2020

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16 January 2020

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16 January 2020

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