Tumor-cell resistance to death receptor--induced apoptosis through mutational inactivation of the proapoptotic Bcl-2 homolog Bax. (Q43903493)

27 November 2017

Tumor-cell resistance to death receptor--induced apoptosis through mutational inactivation of the proapoptotic Bcl-2 homolog Bax. (English)

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27 November 2017

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Heidi LeBlanc

1

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27 November 2017

David Lawrence

2

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27 November 2017

Eugene Varfolomeev

3

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27 November 2017

Klara Totpal

4

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27 November 2017

John Morlan

5

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27 November 2017

Peter Schow

6

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27 November 2017

Sharon Fong

7

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27 November 2017

Ralph Schwall

8

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27 November 2017

Dominick Sinicropi

9

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27 November 2017

Avi Ashkenazi

10

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27 November 2017

language of work or name

English

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publication date

1 March 2002

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27 November 2017

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27 November 2017

8

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27 November 2017

3

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27 November 2017

274-281

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https://scigraph.springernature.com/pub.10.1038/nm0302-274

27 November 2017

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cites work

Death receptors: signaling and modulation

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https://api.crossref.org/works/10.1038%2FNM0302-274

7 January 2021

Apoptotic pathways: paper wraps stone blunts scissors

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https://api.crossref.org/works/10.1038%2FNM0302-274

7 January 2021

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

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https://api.crossref.org/works/10.1038%2FNM0302-274

7 January 2021

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

1 reference

https://api.crossref.org/works/10.1038%2FNM0302-274

7 January 2021

Caspase cleaved BID targets mitochondria and is required for cytochrome c release, while BCL-XL prevents this release but not tumor necrosis factor-R1/Fas death

1 reference

https://api.crossref.org/works/10.1038%2FNM0302-274

7 January 2021

Cross-talk in cell death signaling

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https://api.crossref.org/works/10.1038%2FNM0302-274

7 January 2021

Bid induces the oligomerization and insertion of Bax into the outer mitochondrial membrane

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https://api.crossref.org/works/10.1038%2FNM0302-274

7 January 2021

Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis

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https://api.crossref.org/works/10.1038%2FNM0302-274

7 January 2021

The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues

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https://api.crossref.org/works/10.1038%2FNM0302-274

7 January 2021

Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

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https://api.crossref.org/works/10.1038%2FNM0302-274

7 January 2021

From bench to clinic with apoptosis-based therapeutic agents

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https://api.crossref.org/works/10.1038%2FNM0302-274

7 January 2021

Genetic instabilities in human cancers

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https://api.crossref.org/works/10.1038%2FNM0302-274

7 January 2021

Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype.

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https://api.crossref.org/works/10.1038%2FNM0302-274

7 January 2021

Role of BAX in the apoptotic response to anticancer agents

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https://api.crossref.org/works/10.1038%2FNM0302-274

7 January 2021

Mutational inactivation of the proapoptotic gene BAX confers selective advantage during tumor clonal evolution

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https://api.crossref.org/works/10.1038%2FNM0302-274

7 January 2021

Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5.

1 reference

https://api.crossref.org/works/10.1038%2FNM0302-274

7 January 2021

FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2

1 reference

https://api.crossref.org/works/10.1038%2FNM0302-274

7 January 2021

TRAIL receptor-2 signals apoptosis through FADD and caspase-8

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https://api.crossref.org/works/10.1038%2FNM0302-274

7 January 2021

Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death

1 reference

https://api.crossref.org/works/10.1038%2FNM0302-274

7 January 2021

FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex

1 reference

https://api.crossref.org/works/10.1038%2FNM0302-274

7 January 2021

A matter of life and cell death

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https://api.crossref.org/works/10.1038%2FNM0302-274

7 January 2021

KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene

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https://api.crossref.org/works/10.1038%2FNM0302-274

7 January 2021

Differential modulation of apoptosis sensitivity in CD95 type I and type II cells.

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https://api.crossref.org/works/10.1038%2FNM0302-274

7 January 2021

Genomic amplification of a decoy receptor for Fas ligand in lung and colon cancer

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https://api.crossref.org/works/10.1038%2FNM0302-274

7 January 2021

The inhibitor of death receptor signaling, FLICE-inhibitory protein defines a new class of tumor progression factors

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https://api.crossref.org/works/10.1038%2FNM0302-274

7 January 2021

Immune escape of tumors in vivo by expression of cellular FLICE-inhibitory protein

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https://api.crossref.org/works/10.1038%2FNM0302-274

7 January 2021

Safety and antitumor activity of recombinant soluble Apo2 ligand

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https://api.crossref.org/works/10.1038%2FNM0302-274

7 January 2021

Differential hepatocyte toxicity of recombinant Apo2L/TRAIL versions

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https://api.crossref.org/works/10.1038%2FNM0302-274

7 January 2021

Avoiding premature apoptosis of normal epidermal cells

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https://api.crossref.org/works/10.1038%2FNM0302-274

7 January 2021

Apoptosis control by death and decoy receptors

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https://api.crossref.org/works/10.1038%2FNM0302-274

7 January 2021

Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo.

1 reference

https://api.crossref.org/works/10.1038%2FNM0302-274

7 January 2021

Combined effect of tumor necrosis factor-related apoptosis-inducing ligand and ionizing radiation in breast cancer therapy

1 reference

https://api.crossref.org/works/10.1038%2FNM0302-274

7 January 2021

Locoregional Apo2L/TRAIL eradicates intracranial human malignant glioma xenografts in athymic mice in the absence of neurotoxicity.

1 reference

https://api.crossref.org/works/10.1038%2FNM0302-274

7 January 2021

Isotype-dependent inhibition of tumor growth in vivo by monoclonal antibodies to death receptor 4

1 reference

https://api.crossref.org/works/10.1038%2FNM0302-274

7 January 2021

Tumoricidal activity of a novel anti-human DR5 monoclonal antibody without hepatocyte cytotoxicity.

1 reference

https://api.crossref.org/works/10.1038%2FNM0302-274

7 January 2021

A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry

1 reference

https://api.crossref.org/works/10.1038%2FNM0302-274

7 January 2021

Interaction of CED-4 with CED-3 and CED-9: a molecular framework for cell death

1 reference

https://api.crossref.org/works/10.1038%2FNM0302-274

7 January 2021

Identifiers

DOI

10.1038/NM0302-274

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Dimensions Publication ID

27 November 2017

1024488928

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Fatcat ID

release_sr7onur2wng3rfojq2ylpxugna

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/sr7onur2wng3rfojq2ylpxugna

24 November 2022

mapped directly with Wikidata item

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