IP3 receptor type 2 deficiency is associated with a secretory defect in the pancreatic acinar cell and an accumulation of zymogen granules (Q34489671)

2 August 2017

IP3 receptor type 2 deficiency is associated with a secretory defect in the pancreatic acinar cell and an accumulation of zymogen granules (English)

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2 August 2017

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Abrahim I Orabi

1

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2 August 2017

Yuhuan Luo

2

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2 August 2017

Mahwish U Ahmad

3

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2 August 2017

Ahsan U Shah

4

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2 August 2017

Zahir Mannan

5

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2 August 2017

Dong Wang

6

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2 August 2017

Sheharyar Sarwar

7

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2 August 2017

Kamaldeen A Muili

8

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2 August 2017

Christine Shugrue

9

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2 August 2017

Thomas R Kolodecik

10

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2 August 2017

Vijay P Singh

11

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2 August 2017

Mark E Lowe

12

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2 August 2017

Edwin Thrower

13

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2 August 2017

Ju Chen

14

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2 August 2017

Sohail Z Husain

15

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2 August 2017

language of work or name

English

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publication date

21 November 2012

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2 August 2017

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2 August 2017

7

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2 August 2017

e48465

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2 August 2017

11

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Creative Commons Attribution 4.0 International

2 August 2017

start time

21 November 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3504040/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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6 July 2018

Genetics of pancreatitis

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Vesicle-associated membrane protein 8 (VAMP8) is a SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) selectively required for sequential granule-to-granule fusion

6 July 2018

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Novel characterization of drug-associated pancreatitis in children

6 July 2018

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InsP₃receptors and Orai channels in pancreatic acinar cells: co-localization and its consequences

6 July 2018

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Calmodulin protects against alcohol-induced pancreatic trypsinogen activation elicited via Ca2+ release through IP3 receptors

6 July 2018

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Ethanol enhances carbachol-induced protease activation and accelerates Ca2+ waves in isolated rat pancreatic acini

6 July 2018

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6 July 2018

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Dantrolene mitigates caerulein-induced pancreatitis in vivo in mice

6 July 2018

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Pancreatic protease activation by alcohol metabolite depends on Ca2+ release via acid store IP3 receptors

6 July 2018

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The type 2 inositol (1,4,5)-trisphosphate (InsP3) receptor determines the sensitivity of InsP3-induced Ca2+ release to ATP in pancreatic acinar cells

6 July 2018

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VAMP8 is the v-SNARE that mediates basolateral exocytosis in a mouse model of alcoholic pancreatitis

6 July 2018

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Polarized calcium signaling in exocrine gland cells

6 July 2018

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6 July 2018

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6 July 2018

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The spatial distribution of inositol 1,4,5-trisphosphate receptor isoforms shapes Ca2+ waves.

6 July 2018

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Cyclic AMP-dependent protein kinase and Epac mediate cyclic AMP responses in pancreatic acini

6 July 2018

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VAMP8/endobrevin as a general vesicular SNARE for regulated exocytosis of the exocrine system

6 July 2018

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Suppression of transforming growth factor beta signalling aborts caerulein induced pancreatitis and eliminates restricted stimulation at high caerulein concentrations

6 July 2018

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Clinical practice. Acute pancreatitis

6 July 2018

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IP3 receptor types 2 and 3 mediate exocrine secretion underlying energy metabolism.

6 July 2018

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The ryanodine receptor mediates early zymogen activation in pancreatitis

6 July 2018

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6 July 2018

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Endothelin-1-induced arrhythmogenic Ca2+ signaling is abolished in atrial myocytes of inositol-1,4,5-trisphosphate(IP3)-receptor type 2-deficient mice

6 July 2018

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Effects of increased intracellular cAMP on carbachol-stimulated zymogen activation, secretion, and injury in the pancreatic acinar cell

6 July 2018

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New insights into neurohormonal regulation of pancreatic secretion

6 July 2018

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Subcellular distribution of the inositol 1,4,5-trisphosphate receptors: functional relevance and molecular determinants

6 July 2018

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The minor regulated pathway, a rapid component of salivary secretion, may provide docking/fusion sites for granule exocytosis at the apical surface of acinar cells.

6 July 2018

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High-affinity Ca(2+) binding inhibits autoactivation of rat trypsinogen

6 July 2018

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Hereditary pancreatitis is caused by a mutation in the cationic trypsinogen gene

6 July 2018

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Type I, II, and III inositol 1,4,5-trisphosphate receptors are unequally susceptible to down-regulation and are expressed in markedly different proportions in different cell types

6 July 2018

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Caerulein-induced acute necrotizing pancreatitis in mice: protective effects of proglumide, benzotript, and secretin

6 July 2018

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Cytosolic Ca2+ gradients triggering unidirectional fluid secretion from exocrine pancreas

6 July 2018

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Intracellular Aspects of the Process of Protein Synthesis

6 July 2018

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

6 July 2018

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6 July 2018

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The type II inositol 1,4,5-trisphosphate receptor can trigger Ca2+ waves in rat hepatocytes

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0048465

A role of VAMP8/endobrevin in regulated exocytosis of pancreatic acinar cells

21 January 2018

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Selective exocytosis of zymogen granules induces non-parallel secretion in short-term cholecystokinin-stimulated rats

21 January 2018

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12 December 2020

Exocrine Pancreas: Evidence for Topographic Partition of Secretory Function

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12 December 2020

Pancreatic zymogen granules differ markedly in protein composition

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12 December 2020

Local and global cytosolic Ca2+ oscillations in exocrine cells evoked by agonists and inositol trisphosphate

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12 December 2020

Co-expression in vertebrate tissues and cell lines of multiple inositol 1,4,5-trisphosphate (InsP3) receptors with distinct affinities for InsP3

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12 December 2020

Differences among type I, II, and III inositol-1,4,5-trisphosphate receptors in ligand-binding affinity influence the sensitivity of calcium stores to inositol-1,4,5-trisphosphate

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0048465

Identifiers

DOI

1 reference

release_x67mnqjqibegpivinfd763rkyu

2 August 2017

0 references

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/x67mnqjqibegpivinfd763rkyu

24 November 2022

mapped directly with Wikidata item

PMCID

3504040

1 reference

2 August 2017

1 reference