Mutant mammalian cells as tools to delineate the sterol regulatory element-binding protein pathway for feedback regulation of lipid synthesis (Q34497858)

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English	Mutant mammalian cells as tools to delineate the sterol regulatory element-binding protein pathway for feedback regulation of lipid synthesis	scientific article

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

1 reference

Europe PubMed Central

Mutant mammalian cells as tools to delineate the sterol regulatory element-binding protein pathway for feedback regulation of lipid synthesis (English)

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Joseph L. Goldstein

1

object named as

Joseph L Goldstein

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

author name string

Robert B Rawson

2

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Michael S Brown

3

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Europe PubMed Central

PubMed publication ID

2 August 2017

language of work or name

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publication date

1 January 2002

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Europe PubMed Central

PubMed publication ID

2 August 2017

number of pages

10

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based on heuristic

inferred from page(s)

Archives of Biochemistry and Biophysics

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Europe PubMed Central

PubMed publication ID

2 August 2017

397

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

2

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

139-148

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Familial hypercholesterolemia: identification of a defect in the regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity associated with overproduction of cholesterol

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Nucleotide sequence of 3-hydroxy-3-methyl-glutaryl coenzyme A reductase, a glycoprotein of endoplasmic reticulum

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Appearance of crystalloid endoplasmic reticulum in compactin-resistant Chinese hamster cells with a 500-fold increase in 3-hydroxy-3-methylglutaryl-coenzyme A reductase

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Sterols regulate processing of carbohydrate chains of wild-type SREBP cleavage-activating protein (SCAP), but not sterol-resistant mutants Y298C or D443N.

1 reference

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Regulated step in cholesterol feedback localized to budding of SCAP from ER membranes

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The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor

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Molecular characterization of a membrane transporter for lactate, pyruvate, and other monocarboxylates: implications for the Cori cycle

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Second-site cleavage in sterol regulatory element-binding protein occurs at transmembrane junction as determined by cysteine panning

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Sterol resistance in CHO cells traced to point mutation in SREBP cleavage-activating protein

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Sterols regulate cycling of SREBP cleavage-activating protein (SCAP) between endoplasmic reticulum and Golgi

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Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humans

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Somatic cell genetic and biochemical characterization of cell lines resulting from human genomic DNA transfections of Chinese hamster ovary cell mutants defective in sterol-dependent activation of sterol synthesis and LDL receptor expression

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Identification of a cholesterol-regulated 53,000-dalton cytosolic protein in UT-1 cells and cloning of its cDNA

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Complementation cloning of S2P, a gene encoding a putative metalloprotease required for intramembrane cleavage of SREBPs

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Role of Niemann-Pick type C1 protein in intracellular trafficking of low density lipoprotein-derived cholesterol

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Failure to cleave sterol regulatory element-binding proteins (SREBPs) causes cholesterol auxotrophy in Chinese hamster ovary cells with genetic absence of SREBP cleavage-activating protein.

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Competitive inhibition of 3-hydroxy-3-methylglutaryl coenzyme A reductase by ML-236A and ML-236B fungal metabolites, having hypocholesterolemic activity

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Glycosyltransferase mutants: key to new insights in glycobiology

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SREBP-1, a membrane-bound transcription factor released by sterol-regulated proteolysis

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Molecular identification of the sterol-regulated luminal protease that cleaves SREBPs and controls lipid composition of animal cells

1 reference

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HMG CoA reductase: a negatively regulated gene with unusual promoter and 5' untranslated regions

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Loss of transcriptional activation of three sterol-regulated genes in mutant hamster cells

1 reference

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A receptor-mediated pathway for cholesterol homeostasis

1 reference

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Somatic cell genetics and the study of cholesterol metabolism

1 reference

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Requirement of the Lec35 gene for all known classes of monosaccharide-P-dolichol-dependent glycosyltransferase reactions in mammals

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Transport-Dependent Proteolysis of SREBP

1 reference

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Molecular cloning of 3-hydroxy-3-methylglutaryl coenzyme a reductase and evidence for regulation of its mRNA.

1 reference

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Isolation of cholesterol-requiring mutant Chinese hamster ovary cells with defects in cleavage of sterol regulatory element-binding proteins at site 1.

1 reference

11 October 2022

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Polyene antibiotic-sterol interactions in membranes of Acholeplasma laidlawii cells and lecithin liposomes. 3. Molecular structure of the polyene antibiotic-cholesterol complexes

1 reference

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Sterol regulatory element-binding proteins: activators of cholesterol and fatty acid biosynthesis

1 reference

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Restoration of a regulatory response to low density lipoprotein in acid lipase-deficient human fibroblasts.

1 reference

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Sterol-regulated release of SREBP-2 from cell membranes requires two sequential cleavages, one within a transmembrane segment

1 reference

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Mammalian cell mutant requiring cholesterol and unsaturated fatty acid for growth

1 reference

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Sterol-resistant transcription in CHO cells caused by gene rearrangement that truncates SREBP-2.

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DPM2 regulates biosynthesis of dolichol phosphate-mannose in mammalian cells: correct subcellular localization and stabilization of DPM1, and binding of dolichol phosphate

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Three different rearrangements in a single intron truncate sterol regulatory element binding protein-2 and produce sterol-resistant phenotype in three cell lines. Role of introns in protein evolution

1 reference

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Topology of SREBP cleavage-activating protein, a polytopic membrane protein with a sterol-sensing domain

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Complementary recessive 25-hydroxycholesterol-resistant somatic cell mutants--assay of 25-hydroxycholesterol binding activity.

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Familial hypercholesterolemia: defective binding of lipoproteins to cultured fibroblasts associated with impaired regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity

1 reference

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Autocatalytic processing of site-1 protease removes propeptide and permits cleavage of sterol regulatory element-binding proteins

1 reference

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Cleavage site for sterol-regulated protease localized to a leu-Ser bond in the lumenal loop of sterol regulatory element-binding protein-2.

1 reference

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Further characterization of a Chinese hamster ovary cell mutant defective in lanosterol demethylation

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Isolation and partial characterization of a cholesterol-requiring mutant of Chinese hamster ovary cells

1 reference

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Recurrent G-to-A substitution in a single codon of SREBP cleavage-activating protein causes sterol resistance in three mutant Chinese hamster ovary cell lines.

1 reference

11 October 2022

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A proteolytic pathway that controls the cholesterol content of membranes, cells, and blood

1 reference

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https://opencitations.net/index/coci/api/v1/references/10.1006/ABBI.2001.2615

Regulation of gene expression by SREBP and SCAP.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/ABBI.2001.2615

Cleavage of sterol regulatory element-binding proteins (SREBPs) at site-1 requires interaction with SREBP cleavage-activating protein. Evidence from in vivo competition studies

1 reference

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cDNA cloning of MCT2, a second monocarboxylate transporter expressed in different cells than MCT1.

1 reference

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The proton-linked monocarboxylate transporter (MCT) family: structure, function and regulation

1 reference

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Isolation and characterization of Chinese hamster ovary cell mutants defective in intracellular low density lipoprotein-cholesterol trafficking

1 reference

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Loss of transcriptional repression of three sterol-regulated genes in mutant hamster cells.

1 reference

19 October 2022

https://opencitations.net/index/coci/api/v1/citations/10.1016/S0021-9258(19)84879-2

Identifiers

10.1006/ABBI.2001.2615

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

ResearchGate publication ID

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