Functional regulation of immunoproteasomes and transporter associated with antigen processing (Q34510532)

2 August 2017

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title

Functional regulation of immunoproteasomes and transporter associated with antigen processing (English)

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2 August 2017

L Y Hwang

1

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2 August 2017

P T Lieu

series ordinal

2

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2 August 2017

P A Peterson

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3

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2 August 2017

Y Yang

series ordinal

4

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2 August 2017

1 January 2001

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2 August 2017

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2 August 2017

24

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2 August 2017

3

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2 August 2017

245-272

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https://scigraph.springernature.com/pub.10.1385/ir:24:3:245

2 August 2017

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cites work

Soluble tapasin restores MHC class I expression and function in the tapasin-negative cell line .220.

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12 December 2020

Prominence of beta 2-microglobulin, class I heavy chain conformation, and tapasin in the interactions of class I heavy chain with calreticulin and the transporter associated with antigen processing

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12 December 2020

Identification of proteassemblin, a mammalian homologue of the yeast protein, Ump1p, that is required for normal proteasome assembly

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12 December 2020

Two new proteases in the MHC class I processing pathway

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12 December 2020

Cutting edge: adenovirus E19 has two mechanisms for affecting class I MHC expression.

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12 December 2020

Translocation of long peptides by transporters associated with antigen processing (TAP).

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12 December 2020

Differences in MHC and TAP-1 expression in cervical cancer lymph node metastases as compared with the primary tumours

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12 December 2020

The proteasome activator 11 S REG (PA28) and class I antigen presentation

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12 December 2020

Proteasome complex as a potential cellular target of hepatitis B virus X protein

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12 December 2020

Human transporters associated with antigen processing possess a promiscuous peptide-binding site

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12 December 2020

Proteasomes: multicatalytic proteinase complexes

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12 December 2020

Distinct functions of tapasin revealed by polymorphism in MHC class I peptide loading

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12 December 2020

The type 1 human immunodeficiency virus Tat binding protein is a transcriptional activator belonging to an additional family of evolutionarily conserved genes

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12 December 2020

Assembly of the 26S proteasome is regulated by phosphorylation of the p45/Rpt6 ATPase subunit

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12 December 2020

In vivo assembly of the proteasomal complexes, implications for antigen processing

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12 December 2020

A subcomplex of the proteasome regulatory particle required for ubiquitin-conjugate degradation and related to the COP9-signalosome and eIF3.

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12 December 2020

A critical role for tapasin in the assembly and function of multimeric MHC class I-TAP complexes

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12 December 2020

Interaction of the thiol-dependent reductase ERp57 with nascent glycoproteins

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12 December 2020

Structural and functional effects of PA700 and modulator protein on proteasomes

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12 December 2020

Transcriptional activation of homologous and heterologous genes by the hepatitis B virus X gene product in cells permissive for viral replication

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12 December 2020

Antigen presentation by MHC class I and its regulation by interferon gamma

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12 December 2020

Decrypting class I MHC-bound peptides with peptide libraries

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12 December 2020

Interaction of MHC class I molecules with the transporter associated with antigen processing

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12 December 2020

Defective ribosomal products (DRiPs): a major source of antigenic peptides for MHC class I molecules?

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12 December 2020

Novel propeptide function in 20 S proteasome assembly influences beta subunit composition

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12 December 2020

Assembly and function of the two ABC transporter proteins encoded in the human major histocompatibility complex

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12 December 2020

HBx protein of hepatitis B virus interacts with the C-terminal portion of a novel human proteasome alpha-subunit

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12 December 2020

Structure and functions of the 20S and 26S proteasomes

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12 December 2020

Human transporters associated with antigen processing (TAPs) select epitope precursor peptides for processing in the endoplasmic reticulum and presentation to T cells

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12 December 2020

Selective export of MHC class I molecules from the ER after their dissociation from TAP

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12 December 2020

Dynamics of proteasome distribution in living cells

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12 December 2020

Repression of MHC class I gene promoter activity by two-exon Tat of HIV

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12 December 2020

The thiol oxidoreductase ERp57 is a component of the MHC class I peptide-loading complex.

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12 December 2020

Changes in proteasome localization during the cell cycle

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12 December 2020

The molecular chaperone calnexin facilitates folding and assembly of class I histocompatibility molecules

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12 December 2020

The proteasome, a novel protease regulated by multiple mechanisms

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12 December 2020

Molecular requirements for assembly and intracellular transport of class I major histocompatibility complex molecules.

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12 December 2020

The human cytomegalovirus gene product US6 inhibits ATP binding by TAP

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12 December 2020

A role for the thiol-dependent reductase ERp57 in the assembly of MHC class I molecules

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12 December 2020

The structure of ClpP at 2.3 A resolution suggests a model for ATP-dependent proteolysis

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12 December 2020

Subcellular localization, stoichiometry, and protein levels of 26 S proteasome subunits in yeast

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12 December 2020

Altered expression of TAP-1 and major histocompatibility complex class I in laryngeal papillomatosis: correlation of TAP-1 with disease.

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12 December 2020

An early pseudorabies virus protein down-regulates porcine MHC class I expression by inhibition of transporter associated with antigen processing (TAP).

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12 December 2020

The human major histocompatability complex: lessons from the DNA sequence

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12 December 2020

Interaction with newly synthesized and retained proteins in the endoplasmic reticulum suggests a chaperone function for human integral membrane protein IP90 (calnexin)

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12 December 2020

A functionally defective allele of TAP1 results in loss of MHC class I antigen presentation in a human lung cancer

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12 December 2020

Functional relationship between calreticulin, calnexin, and the endoplasmic reticulum luminal domain of calnexin

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12 December 2020

A cDNA for a protein that interacts with the human immunodeficiency virus Tat transactivator

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12 December 2020

Presentation of viral antigen by MHC class I molecules is dependent on a putative peptide transporter heterodimer

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12 December 2020

A viral inhibitor of peptide transporters for antigen presentation

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12 December 2020

Roles for calreticulin and a novel glycoprotein, tapasin, in the interaction of MHC class I molecules with TAP

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12 December 2020

Hepatitis B virus X protein is both a substrate and a potential inhibitor of the proteasome complex

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12 December 2020

A role for calnexin in the assembly of the MHC class I loading complex in the endoplasmic reticulum

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12 December 2020

Phosphorylated peptides are naturally processed and presented by major histocompatibility complex class I molecules in vivo

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12 December 2020

In vivo regulation of the assembly and intracellular transport of class I major histocompatibility complex molecules

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12 December 2020

ER-60, a chaperone with thiol-dependent reductase activity involved in MHC class I assembly

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12 December 2020

Molecular cloning and expression of a gamma-interferon-inducible activator of the multicatalytic protease

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12 December 2020

Formation of proteasome-PA700 complexes directly correlates with activation of peptidase activity

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12 December 2020

Independent and synergistic effects of disulfide bond formation, beta 2-microglobulin, and peptides on class I MHC folding and assembly in an in vitro translation system

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12 December 2020

HIV-1 tat binds TAFII250 and represses TAFII250-dependent transcription of major histocompatibility class I genes

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12 December 2020

Intracellular localization of proteasomal degradation of a viral antigen

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12 December 2020

Head-head/tail-tail relative orientation of the pore-forming domains of the heterodimeric ABC transporter TAP

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12 December 2020

A gated channel into the proteasome core particle

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12 December 2020

A giant protease with potential to substitute for some functions of the proteasome

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12 December 2020

HBx gene of hepatitis B virus induces liver cancer in transgenic mice

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12 December 2020

The thiol-dependent reductase ERp57 interacts specifically with N-glycosylated integral membrane proteins

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12 December 2020

Rapid degradation of a large fraction of newly synthesized proteins by proteasomes.

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12 December 2020

Impairment of the ubiquitin-proteasome system by protein aggregation

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12 December 2020

New human gene encoding a positive modulator of HIV Tat-mediated transactivation

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12 December 2020

Crystal structure of the 20S proteasome from the archaeon T. acidophilum at 3.4 A resolution

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12 December 2020

Impaired immunoproteasome assembly and immune responses in PA28-/- mice.

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12 December 2020

The HBV X-ORF encodes a transactivator: a potential factor in viral hepatocarcinogenesis.

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12 December 2020

Identification and characterization of a mammalian protein interacting with 20S proteasome precursors

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12 December 2020

Proteasome active sites allosterically regulate each other, suggesting a cyclical bite-chew mechanism for protein breakdown

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12 December 2020

The multicatalytic proteinase complex, a major extralysosomal proteolytic system

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12 December 2020

Herpes simplex virus turns off the TAP to evade host immunity

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12 December 2020

Transcriptional regulation of the major histocompatibility complex (MHC) class I heavy chain, TAP1 and LMP2 genes by the human papillomavirus (HPV) type 6b, 16 and 18 E7 oncoproteins.

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12 December 2020

Molecular mechanisms of class I major histocompatibility complex antigen processing and presentation

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12 December 2020

Does HIV-1 Tat induce a change in viral initiation rights?

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12 December 2020

Efficient dissociation of the p88 chaperone from major histocompatibility complex class I molecules requires both beta 2-microglobulin and peptide

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12 December 2020

Characterisation of the newly identified human Ump1 homologue POMP and analysis of LMP7(beta 5i) incorporation into 20 S proteasomes

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12 December 2020

Interaction of the UV-damaged DNA-binding protein with hepatitis B virus X protein is conserved among mammalian hepadnaviruses and restricted to transactivation-proficient X-insertion mutants

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12 December 2020

The N-terminal region of tapasin is required to stabilize the MHC class I loading complex

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12 December 2020

Differential regulation of Dk and Kk major histocompatibility complex class I proteins on the cell surface after infection of murine cells by pseudorabies virus

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12 December 2020

The proteasome: paradigm of a self-compartmentalizing protease

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12 December 2020

Tyrosine phosphorylated p91 binds to a single element in the ISGF2/IRF-1 promoter to mediate induction by IFN alpha and IFN gamma, and is likely to autoregulate the p91 gene.

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12 December 2020

Crystal structures of two viral peptides in complex with murine MHC class I H-2Kb

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12 December 2020

Mechanisms of MHC class I--restricted antigen processing

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12 December 2020

Functional requirement for class I MHC in CNS development and plasticity

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12 December 2020

Structural and functional characterization of interaction between hepatitis B virus X protein and the proteasome complex

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12 December 2020

Expression of protein kinase A and protein kinase C during ongoing human cytomegalovirus infection.

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12 December 2020

Association of immunoproteasomes with the endoplasmic reticulum

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12 December 2020

Sequences encoded in the class II region of the MHC related to the 'ABC' superfamily of transporters

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12 December 2020

Endoplasmic reticulum resident protein of 90 kilodaltons associates with the T- and B-cell antigen receptors and major histocompatibility complex antigens during their assembly

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12 December 2020

MHC class I molecules form ternary complexes with calnexin and TAP and undergo peptide-regulated interaction with TAP via their extracellular domains

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12 December 2020

Assembly of tapasin-associated MHC class I in the absence of the transporter associated with antigen processing (TAP).

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12 December 2020

gamma-Interferon decreases the level of 26 S proteasomes and changes the pattern of phosphorylation

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12 December 2020

ABC Transporters: From Microorganisms to Man

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12 December 2020

Recognition DNA sequences of interferon regulatory factor 1 (IRF-1) and IRF-2, regulators of cell growth and the interferon system

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12 December 2020

Chaperone selection during glycoprotein translocation into the endoplasmic reticulum.

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12 December 2020

Maturation of mammalian 20 S proteasome: purification and characterization of 13 S and 16 S proteasome precursor complexes.

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12 December 2020

Interferon gamma regulates accumulation of the proteasome activator PA28 and immunoproteasomes at nuclear PML bodies

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12 December 2020

Enhanced Catalysis of Ribonuclease B Folding by the Interaction of Calnexin or Calreticulin with ERp57

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12 December 2020

Distinct functional properties of the TAP subunits coordinate the nucleotide-dependent transport cycle

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12 December 2020

Species-specific differences in chaperone interaction of human and mouse major histocompatibility complex class I molecules

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12 December 2020

Molecular dynamics of MHC genesis unraveled by sequence analysis of the 1,796,938-bp HLA class I region

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12 December 2020

The basis of multidrug resistance in mammalian cells: homology with bacterial transport

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12 December 2020

Two putative subunits of a peptide pump encoded in the human major histocompatibility complex class II region

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12 December 2020

Competitor analogs for defined T cell antigens: peptides incorporating a putative binding motif and polyproline or polyglycine spacers

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12 December 2020

Subunit stoichiometry and three-dimensional arrangement in proteasomes from Thermoplasma acidophilum

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12 December 2020

Ump1p is required for proper maturation of the 20S proteasome and becomes its substrate upon completion of the assembly.

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12 December 2020

The hepatitis B virus X-gene product trans-activates both RNA polymerase II and III promoters

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12 December 2020

The multicatalytic and 26 S proteases

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12 December 2020

A 26 S protease subunit that binds ubiquitin conjugates

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12 December 2020

Regulation of HIV expression: mechanisms of action of Tat and Rev.

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12 December 2020

Nucleotide binding by TAP mediates association with peptide and release of assembled MHC class I molecules

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12 December 2020

LMP-associated proteolytic activities and TAP-dependent peptide transport for class 1 MHC molecules are suppressed in cell lines transformed by the highly oncogenic adenovirus 12.

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12 December 2020

Impaired immune responses and altered peptide repertoire in tapasin-deficient mice

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12 December 2020

Frequency of down-regulation of individual HLA-A and -B alleles in cervical carcinomas in relation to TAP-1 expression

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12 December 2020

Subcellular localization of proteasomes and their regulatory complexes in mammalian cells.

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12 December 2020

Regulation of MHC class I transport by the molecular chaperone, calnexin (p88, IP90).

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12 December 2020

Retention of empty MHC class I molecules by tapasin is essential to reconstitute antigen presentation in invertebrate cells

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12 December 2020

Molecular biology of the proteasome.

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12 December 2020

Conformational changes induced in the MHC class I molecule by peptide and beta 2-microglobulin

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12 December 2020

Primary structures of two homologous subunits of PA28, a gamma-interferon-inducible protein activator of the 20S proteasome

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12 December 2020

The major substrates for TAP in vivo are derived from newly synthesized proteins

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12 December 2020

Membrane topology and dimerization of the two subunits of the transporter associated with antigen processing reveal a three-domain structure

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12 December 2020

The human papillomavirus E7 oncoprotein functionally interacts with the S4 subunit of the 26 S proteasome

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12 December 2020

Regulatory proteins of the proteasome.

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12 December 2020

Location of MHC-encoded transporters in the endoplasmic reticulum and cis-Golgi.

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12 December 2020

Hepatitis B virus HBx protein activates Ras-GTP complex formation and establishes a Ras, Raf, MAP kinase signaling cascade

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12 December 2020

MHC class I/beta 2-microglobulin complexes associate with TAP transporters before peptide binding

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12 December 2020

Integration of the ubiquitin-proteasome pathway with a cytosolic oligopeptidase activity

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12 December 2020

HIV Tat represses transcription through Sp1-like elements in the basal promoter

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12 December 2020

Heat shock protein 70 moderately enhances peptide binding and transport by the transporter associated with antigen processing

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12 December 2020

Genes encoded in the major histocompatibility complex affecting the generation of peptides for TAP transport

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12 December 2020

The chicken B locus is a minimal essential major histocompatibility complex.

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12 December 2020

Impaired assembly yet normal trafficking of MHC class I molecules in Tapasin mutant mice

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12 December 2020

Effects on NF-kappa B1/p105 processing of the interaction between the HTLV-1 transactivator Tax and the proteasome

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12 December 2020

Characteristics of peptide and major histocompatibility complex class I/beta 2-microglobulin binding to the transporters associated with antigen processing (TAP1 and TAP2)

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12 December 2020

PA28 activator protein forms regulatory caps on proteasome stacked rings.

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12 December 2020

Phosphorylated peptides can be transported by TAP molecules, presented by class I MHC molecules, and recognized by phosphopeptide-specific CTL.

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12 December 2020

Identifiers

DOI

10.1385/IR:24:3:245

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Dimensions Publication ID

2 August 2017

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