Highly mutagenic exocyclic DNA adducts are substrates for the human nucleotide incision repair pathway (Q34517201)

2 August 2017

Highly mutagenic exocyclic DNA adducts are substrates for the human nucleotide incision repair pathway (English)

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2 August 2017

Paulina Prorok

1

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Alexander Ishchenko

object named as

Alexander A Ishchenko

5

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Olga S. Fedorova

object named as

Olga S Fedorova

4

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Barbara Tudek

8

object named as

Barbara Tudek

1 reference

2 August 2017

Christine Saint-Pierre

2

1 reference

2 August 2017

Didier Gasparutto

3

1 reference

2 August 2017

Hervé Leh

6

1 reference

2 August 2017

Malcolm Buckle

7

1 reference

2 August 2017

Murat Saparbaev

9

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2 August 2017

language of work or name

English

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publication date

14 December 2012

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2 August 2017

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2 August 2017

7

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2 August 2017

12

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2 August 2017

e51776

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Creative Commons Attribution 4.0 International

2 August 2017

start time

14 December 2012

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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describes a project that uses

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3522590/fullTextXML

inferred from PubMed Central ID database lookup

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New insights in the removal of the hydantoins, oxidation product of pyrimidines, via the base excision and nucleotide incision repair pathways.

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Genetic and biochemical characterization of human AP endonuclease 1 mutants deficient in nucleotide incision repair activity

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Selective Incision of the alpha-N-Methyl-Formamidopyrimidine Anomer by Escherichia coli Endonuclease IV.

7 July 2018

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Intrusion of a DNA repair protein in the RNome world: is this the beginning of a new era?

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7 July 2018

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Human AP endonuclease 1 stimulates multiple-turnover base excision by alkyladenine DNA glycosylase

7 July 2018

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Targeted deletion of the genes encoding NTH1 and NEIL1 DNA N-glycosylases reveals the existence of novel carcinogenic oxidative damage to DNA.

7 July 2018

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Base excision repair of oxidative DNA damage and association with cancer and aging

7 July 2018

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AlkB homologue 2-mediated repair of ethenoadenine lesions in mammalian DNA.

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Base excision DNA repair

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7 July 2018

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The intricate structural chemistry of base excision repair machinery: implications for DNA damage recognition, removal, and repair.

7 July 2018

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Uncoupling of the base excision and nucleotide incision repair pathways reveals their respective biological roles.

7 July 2018

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Direct repair of the exocyclic DNA adduct 1,N6-ethenoadenine by the DNA repair AlkB proteins

7 July 2018

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AlkB reverses etheno DNA lesions caused by lipid oxidation in vitro and in vivo

7 July 2018

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Molecular and biological roles of Ape1 protein in mammalian base excision repair

7 July 2018

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Two essential but distinct functions of the mammalian abasic endonuclease

7 July 2018

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Spontaneous mutagenesis is enhanced in Apex heterozygous mice

7 July 2018

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Human apurinic endonuclease 1 (APE1) expression and prognostic significance in osteosarcoma: enhanced sensitivity of osteosarcoma to DNA damaging agents using silencing RNA APE1 expression inhibition

7 July 2018

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Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints

7 July 2018

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Structural insights by molecular dynamics simulations into specificity of the major human AP endonuclease toward the benzene-derived DNA adduct, pBQ-C.

7 July 2018

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DNA glycosylase recognition and catalysis

7 July 2018

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Differential specificity of human and Escherichia coli endonuclease III and VIII homologues for oxidative base lesions

7 July 2018

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The major human AP endonuclease (Ape1) is involved in the nucleotide incision repair pathway.

7 July 2018

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A back-up glycosylase in Nth1 knock-out mice is a functional Nei (endonuclease VIII) homologue

7 July 2018

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Targeted deletion of mNth1 reveals a novel DNA repair enzyme activity.

7 July 2018

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The pyrimidine ring-opened derivative of 1,N6-ethenoadenine is excised from DNA by the Escherichia coli Fpg and Nth proteins

7 July 2018

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Ultrasensitive and specific detection methods for exocylic DNA adducts: markers for lipid peroxidation and oxidative stress

7 July 2018

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Abasic site recognition by two apurinic/apyrimidinic endonuclease families in DNA base excision repair: the 3' ends justify the means

7 July 2018

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Substrate specificity of human methylpurine DNA N-glycosylase

7 July 2018

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DNA-bound structures and mutants reveal abasic DNA binding by APE1 and DNA repair coordination [corrected]

7 July 2018

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Excision of 5,6-dihydroxy-5,6-dihydrothymine, 5,6-dihydrothymine, and 5-hydroxycytosine from defined sequence oligonucleotides by Escherichia coli endonuclease III and Fpg proteins: kinetic and mechanistic aspects

7 July 2018

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Human thymine DNA glycosylase binds to apurinic sites in DNA but is displaced by human apurinic endonuclease 1.

7 July 2018

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A 55-kDa protein isolated from human cells shows DNA glycosylase activity toward 3,N4-ethenocytosine and the G/T mismatch

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522590

3,N4-ethenocytosine, a highly mutagenic adduct, is a primary substrate for Escherichia coli double-stranded uracil-DNA glycosylase and human mismatch-specific thymine-DNA glycosylase

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522590

Targeted deletion of alkylpurine-DNA-N-glycosylase in mice eliminates repair of 1,N6-ethenoadenine and hypoxanthine but not of 3,N4-ethenocytosine or 8-oxoguanine

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522590

In vitro repair of oxidative DNA damage by human nucleotide excision repair system: possible explanation for neurodegeneration in xeroderma pigmentosum patients

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522590

The redox/DNA repair protein, Ref-1, is essential for early embryonic development in mice.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522590

1,N6-ethenodeoxyadenosine, a DNA adduct highly mutagenic in mammalian cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522590

The biochemical basis of zinc physiology

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522590

Mutagenic potency of exocyclic DNA adducts: marked differences between Escherichia coli and simian kidney cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522590

Repair of oxidative damage to DNA: enzymology and biology

7 July 2018

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Dihaloalkanes and polyhaloalkenes

7 July 2018

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A role for the human DNA repair enzyme HAP1 in cellular protection against DNA damaging agents and hypoxic stress

7 July 2018

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Alpha-deoxyadenosine, a major anoxic radiolysis product of adenine in DNA, is a substrate for Escherichia coli endonuclease IV.

7 July 2018

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Deoxyhexanucleotide containing a vinyl chloride induced DNA lesion, 1,N6-ethenoadenine: synthesis, physical characterization, and incorporation into a duplex bacteriophage M13 genome as part of an amber codon

7 July 2018

1 reference

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Roles of etheno-DNA adducts in tumorigenicity of olefins

7 July 2018

1 reference

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Substrate specificity of the Escherichia coli Fpg protein (formamidopyrimidine-DNA glycosylase): excision of purine lesions in DNA produced by ionizing radiation or photosensitization.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522590

Both purified human 1,N6-ethenoadenine-binding protein and purified human 3-methyladenine-DNA glycosylase act on 1,N6-ethenoadenine and 3-methyladenine

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522590

Redox activation of Fos-Jun DNA binding activity is mediated by a DNA repair enzyme

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522590

Mutagenic and genotoxic effects of three vinyl chloride-induced DNA lesions: 1,N6-ethenoadenine, 3,N4-ethenocytosine, and 4-amino-5-(imidazol-2-yl)imidazole.

7 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0051776

Alternative nucleotide incision repair pathway for oxidative DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0051776

Alpha-anomeric deoxynucleotides, anoxic products of ionizing radiation, are substrates for the endonuclease IV-type AP endonucleases

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0051776

Major oxidative products of cytosine are substrates for the nucleotide incision repair pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0051776

The exonuclease activity of human apurinic/apyrimidinic endonuclease (APE1). Biochemical properties and inhibition by the natural dinucleotide Gp4G.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0051776

A murine AP-endonuclease gene-targeted deficiency with post-implantation embryonic progression and ionizing radiation sensitivity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0051776

UV-induced photolesions elicit ATR-kinase-dependent signaling in non-cycling cells through nucleotide excision repair-dependent and -independent pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0051776

Hijacking of the human alkyl-N-purine-DNA glycosylase by 3,N4-ethenocytosine, a lipid peroxidation-induced DNA adduct

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0051776

Increased formation and persistence of 1,N(6)-ethenoadenine in DNA is not associated with higher susceptibility to carcinogenesis in alkylpurine-DNA-N-glycosylase knockout mice treated with vinyl carbamate.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522590

Mutagenesis induced by a single 1,N6-ethenodeoxyadenosine adduct in human cells.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522590

Database of mouse strains carrying targeted mutations in genes affecting biological responses to DNA damage Version 7

27 October 2018

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12 December 2020

1,N6-ethenodeoxyadenosine and 3,N4-ethenodeoxycytine in liver DNA from humans and untreated rodents detected by immunoaffinity/32P-postlabeling

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12 December 2020

Mutagenicity of site-specifically located 1,N2-ethenoguanine in Chinese hamster ovary cell chromosomal DNA

1 reference

12 December 2020

Biological Responses of Human Apurinic Endonuclease to Radiation‐Induced DNA Damage

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12 December 2020

10.1371/JOURNAL.PONE.0051776

Identifiers

DOI

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2 August 2017

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2 August 2017

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