Functional cell-based uHTS in chemical genomic drug discovery (Q34527983)

2 August 2017

1 reference

title

Functional cell-based uHTS in chemical genomic drug discovery (English)

1 reference

2 August 2017

1 reference

Glenn E Croston

1

1 reference

2 August 2017

1 March 2002

1 reference

2 August 2017

Trends in Biotechnology

1 reference

2 August 2017

20

1 reference

2 August 2017

3

1 reference

2 August 2017

110-115

1 reference

Drug discovery: a historical perspective

2 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2901906-6

7 January 2021

Initial sequencing and analysis of the human genome

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2901906-6

7 January 2021

The Sequence of the Human Genome

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2901906-6

7 January 2021

HTS in the new millennium: the role of pharmacology and flexibility

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2901906-6

7 January 2021

High-throughput and ultra-high-throughput screening: solution- and cell-based approaches

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2901906-6

7 January 2021

New assay technologies for high-throughput screening

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2901906-6

7 January 2021

Intracellular detection assays for high-throughput screening

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2901906-6

7 January 2021

Too many targets, not enough target validation

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2901906-6

7 January 2021

Transgenic gene knock-outs: functional genomics and therapeutic target selection

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2901906-6

7 January 2021

The impact of genomics on drug discovery

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2901906-6

7 January 2021

Differences between natural and recombinant G protein-coupled receptor systems with varying receptor/G protein stoichiometry

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2901906-6

7 January 2021

Orphan G-protein-coupled receptors and natural ligand discovery

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2901906-6

7 January 2021

Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2901906-6

7 January 2021

Human urotensin-II is a potent vasoconstrictor and agonist for the orphan receptor GPR14

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2901906-6

7 January 2021

Molecular medicine. The cholesterol quartet

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2901906-6

7 January 2021

Drug discovery and the intracellular receptor family

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2901906-6

7 January 2021

High throughput assays of cloned adrenergic, muscarinic, neurokinin, and neurotrophin receptors in living mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2901906-6

7 January 2021

Tools for investigating functional interactions between ligands and G-protein-coupled receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2901906-6

7 January 2021

Amphibian Melanophore Technology as a Functional Screen for Antagonists of G-Protein Coupled 7-Transmembrane Receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2901906-6

7 January 2021

Use of a cell-based, lawn format assay to rapidly screen a 442,368 bead-based peptide library

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2901906-6

7 January 2021

Functional characterization of agonists at recombinant human 5-HT2A, 5-HT2B and 5-HT2C receptors in CHO-K1 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2901906-6

7 January 2021

A bioluminescent assay for agonist activity at potentially any G-protein-coupled receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2901906-6

7 January 2021

Quantitation of transcription and clonal selection of single living cells with beta-lactamase as reporter

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2901906-6

7 January 2021

High Throughput Quantitation of cAMP Production Mediated by Activation of Seven Transmembrane Domain Receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2901906-6

7 January 2021

Development of a functional reporter gene HTS assay for the identification of mGluR7 modulators

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2901906-6

7 January 2021

A novel high throughput chemiluminescent assay for the measurement of cellular cyclic adenosine monophosphate levels

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2901906-6

7 January 2021

Fluorescent indicators for Ca2+ based on green fluorescent proteins and calmodulin

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2901906-6

7 January 2021

A genetically encoded, fluorescent indicator for cyclic AMP in living cells

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2901906-6

7 January 2021

Cell-based assays and instrumentation for screening ion-channel targets

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2901906-6

7 January 2021

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2901906-6

7 January 2021

Paclitaxel (Taxol): a success story with valuable lessons for natural product drug discovery and development

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2802%2901906-6

7 January 2021

10.1016/S0167-7799(02)01906-6

Identifiers

DOI

1 reference

2 August 2017

1 reference

PubMed ID

11841862