Differential SERM effects on corepressor binding dictate ERalpha activity in vivo (Q34529817)

2 August 2017

Differential SERM effects on corepressor binding dictate ERalpha activity in vivo (English)

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2 August 2017

Paul Webb

1

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2 August 2017

Phuong Nguyen

series ordinal

2

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2 August 2017

Peter J Kushner

series ordinal

3

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2 August 2017

language of work or name

English

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publication date

13 December 2002

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Journal of Biological Chemistry

2 August 2017

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2 August 2017

278

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2 August 2017

9

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2 August 2017

6912-6920

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Estrogen receptor transcription and transactivation: Estrogen receptor alpha and estrogen receptor beta: regulation by selective estrogen receptor modulators and importance in breast cancer

2 August 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208501200

Tamoxifen activation of the estrogen receptor/AP-1 pathway: potential origin for the cell-specific estrogen-like effects of antiestrogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208501200

Transcriptional activation of genes by 17 beta-estradiol through estrogen receptor-Sp1 interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208501200

Opposing action of estrogen receptors alpha and beta on cyclin D1 gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208501200

Molecular determinants for the tissue specificity of SERMs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208501200

Selective estrogen receptor modulation and reduction in risk of breast cancer, osteoporosis, and coronary heart disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208501200

Hormone-dependent coactivator binding to a hydrophobic cleft on nuclear receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208501200

Molecular determinants of the estrogen receptor-coactivator interface

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208501200

Molecular basis of agonism and antagonism in the oestrogen receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208501200

The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208501200

Structure of the ligand-binding domain of oestrogen receptor beta in the presence of a partial agonist and a full antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208501200

Structural characterization of a subtype-selective ligand reveals a novel mode of estrogen receptor antagonism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208501200

Structural insights into the mode of action of a pure antiestrogen

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208501200

The secrets of selective estrogen receptor modulation: cell-specific coregulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208501200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208501200

An antiestrogen-responsive estrogen receptor-alpha mutant (D351Y) shows weak AF-2 activity in the presence of tamoxifen

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208501200

Peptide antagonists of the human estrogen receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208501200

Estrogen receptor activation function 1 works by binding p160 coactivator proteins

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M208501200

Activation of the estrogen receptor through phosphorylation by mitogen-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208501200

AIB1 is a conduit for kinase-mediated growth factor signaling to the estrogen receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208501200

Potentiation of estrogen receptor activation function 1 (AF-1) by Src/JNK through a serine 118-independent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208501200

Comparative analyses of mechanistic differences among antiestrogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208501200

Differential ligand activation of estrogen receptors ERalpha and ERbeta at AP1 sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208501200

Unique protein determinants of the subtype-selective ligand responses of the estrogen receptors (ERalpha and ERbeta ) at AP-1 sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208501200

Estrogen receptor binding to DNA is not required for its activity through the nonclassical AP1 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208501200

Estrogen receptor pathways to AP-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208501200

Antiestrogen ICI 164,384 reduces cellular estrogen receptor content by increasing its turnover

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208501200

Examination of the DNA-binding ability of estrogen receptor in whole cells: implications for hormone-independent transactivation and the actions of antiestrogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208501200

The partial agonist activity of antagonist-occupied steroid receptors is controlled by a novel hinge domain-binding coactivator L7/SPA and the corepressors N-CoR or SMRT

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208501200

Diverse signaling pathways modulate nuclear receptor recruitment of N-CoR and SMRT complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208501200

The tamoxifen-responsive estrogen receptor alpha mutant D351Y shows reduced tamoxifen-dependent interaction with corepressor complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208501200

Cofactor dynamics and sufficiency in estrogen receptor-regulated transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208501200

Identification of a negative regulatory surface within estrogen receptor alpha provides evidence in support of a role for corepressors in regulating cellular responses to agonists and antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208501200

Titration by estrogen receptor activation function-2 of targets that are downstream from coactivators

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208501200

TR surfaces and conformations required to bind nuclear receptor corepressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208501200

Selective Interaction of hsp90 with an Estrogen Receptor Ligand-binding Domain Containing a Point Mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208501200

Identification and characterization of a novel corepressor interaction region in RVR and Rev-erbA alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208501200

The CoRNR motif controls the recruitment of corepressors by nuclear hormone receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208501200

Mechanism of corepressor binding and release from nuclear hormone receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208501200

Molecular determinants of nuclear receptor-corepressor interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208501200

Structure and specificity of nuclear receptor-coactivator interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208501200

An estrogen receptor-selective coregulator that potentiates the effectiveness of antiestrogens and represses the activity of estrogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208501200

Structural basis for antagonist-mediated recruitment of nuclear co-repressors by PPARalpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208501200

Rational design and synthesis of a novel thyroid hormone antagonist that blocks coactivator recruitment

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208501200

The nuclear corepressors NCoR and SMRT are key regulators of both ligand- and 8-bromo-cyclic AMP-dependent transcriptional activity of the human progesterone receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208501200

FRA-1 expression level modulates regulation of activator protein-1 activity by estradiol in breast cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208501200

Effect of antagonists on DNA binding properties of the human estrogen receptor in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208501200

21 January 2018

Identifiers

DOI

10.1074/JBC.M208501200

1 reference

2 August 2017

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