Loci identified by genome-wide association studies influence different disease-related phenotypes in chronic obstructive pulmonary disease (Q34535065)

2 August 2017

Loci identified by genome-wide association studies influence different disease-related phenotypes in chronic obstructive pulmonary disease (English)

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genome-wide association study

2 August 2017

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chronic obstructive pulmonary disease

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Lisa D Edwards

3

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Xiangyang Kong

2

object named as

Xiangyang Kong

1 reference

2 August 2017

Sreekumar G Pillai

1

1 reference

2 August 2017

Michael H Cho

4

1 reference

2 August 2017

Wayne H Anderson

5

1 reference

2 August 2017

Harvey O Coxson

6

1 reference

2 August 2017

David A Lomas

7

1 reference

2 August 2017

Edwin K Silverman

8

1 reference

2 August 2017

ECLIPSE and ICGN Investigators

9

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2 August 2017

language of work or name

English

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publication date

23 July 2010

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American Journal of Respiratory and Critical Care Medicine

2 August 2017

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2 August 2017

182

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2 August 2017

1498-1505

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2 August 2017

12

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Meta-analysis and imputation refines the association of 15q25 with smoking quantity

2 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3029936

Variants in FAM13A are associated with chronic obstructive pulmonary disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3029936

Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3029936

Genome-wide association study identifies five loci associated with lung function

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3029936

Integration of genomic and genetic approaches implicates IREB2 as a COPD susceptibility gene

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3029936

Systemic manifestations and comorbidities of COPD.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3029936

A genome-wide association study in chronic obstructive pulmonary disease (COPD): identification of two major susceptibility loci.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3029936

Polymorphic variation in surfactant protein B is associated with COPD exacerbations.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3029936

Genetic variation in the CHRNA5 gene affects mRNA levels and is associated with risk for alcohol dependence

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3029936

Genome-wide association analysis identifies 20 loci that influence adult height

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3029936

A variant associated with nicotine dependence, lung cancer and peripheral arterial disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3029936

A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3029936

Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3029936

Alpha-5/alpha-3 nicotinic receptor subunit alleles increase risk for heavy smoking

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3029936

A new MALDI-TOF-based assay for monitoring JAK2 V617F mutation level in patients undergoing allogeneic stem cell transplantation (allo SCT) for classic myeloproliferative disorders (MPD).

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3029936

The non-neuronal cholinergic system in the airways: an unappreciated regulatory role in pulmonary inflammation?

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3029936

New molecular targets for the treatment of neutrophilic diseases

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3029936

Cholinergic nicotinic receptor genes implicated in a nicotine dependence association study targeting 348 candidate genes with 3713 SNPs

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3029936

Nicotine-mediated cell proliferation and angiogenesis: new twists to an old story

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3029936

Nicotine induces cell proliferation by beta-arrestin-mediated activation of Src and Rb-Raf-1 pathways

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3029936

The role of iron regulatory proteins in mammalian iron homeostasis and disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3029936

Outcomes and markers in the assessment of chronic obstructive pulmonary disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3029936

The body-mass index, airflow obstruction, dyspnea, and exercise capacity index in chronic obstructive pulmonary disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3029936

Rapid Akt activation by nicotine and a tobacco carcinogen modulates the phenotype of normal human airway epithelial cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3029936

Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. NHLBI/WHO Global Initiative for Chronic Obstructive Lung Disease (GOLD) Workshop summary

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3029936

Genetic epidemiology of severe, early-onset chronic obstructive pulmonary disease. Risk to relatives for airflow obstruction and chronic bronchitis.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3029936

Non-neuronal acetylcholine, a locally acting molecule, widely distributed in biological systems: expression and function in humans

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3029936

Alternative projections of mortality and disability by cause 1990-2020: Global Burden of Disease Study

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3029936

Opioids induce while nicotine suppresses apoptosis in human lung cancer cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3029936

Genotypic and phenotypic similarities in pulmonary function among family members of adult monozygotic and dizygotic twins

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3029936

Bedside methods versus dual energy X-ray absorptiometry for body composition measurement in COPD.

7 July 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201002-0151OC

Airway wall thickening and emphysema show independent familial aggregation in chronic obstructive pulmonary disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201002-0151OC

PBAT: tools for family-based association studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201002-0151OC

Prediction of risk of COPD exacerbations by the BODE index.

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201002-0151OC

Serum surfactant protein D is steroid sensitive and associated with exacerbations of COPD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201002-0151OC

[(3)H]Nicotine binding in peripheral blood cells of smokers is correlated with the number of cigarettes smoked per day.

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201002-0151OC

Effects of nicotine on intercellular adhesion molecule expression in endothelial cells and integrin expression in neutrophils in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201002-0151OC

Nicotine prolongs neutrophil survival by suppressing apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201002-0151OC

Evaluation of COPD Longitudinally to Identify Predictive Surrogate End-points (ECLIPSE)

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201002-0151OC

Obstructive Lung Disease and Trypsin Inhibitors in α1-Antitrypsin Deficiency

21 January 2018

1 reference

12 December 2020

Familial factors related to lung function in children aged 6-10 years. Results from the PAARC epidemiologic study

1 reference

12 December 2020

Cigarette smoking and health. American Thoracic Society

1 reference

12 December 2020

A single nucleotide polymorphism in the CCL1 gene predicts acute exacerbations in chronic obstructive pulmonary disease

1 reference

12 December 2020

Siblings of patients with severe chronic obstructive pulmonary disease have a significant risk of airflow obstruction

1 reference

12 December 2020

Family aggregation of pulmonary function measurements

1 reference

12 December 2020

10.1164/RCCM.201002-0151OC

Identifiers

DOI

1 reference

2 August 2017

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2 August 2017

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