Cdk5 behind the wheel: a role in trafficking and transport? (Q34537614)

2 August 2017

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title

Cdk5 behind the wheel: a role in trafficking and transport? (English)

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2 August 2017

2

Li Huei Tsai

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2 August 2017

Deanna S Smith

1

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2 August 2017

publication date

1 January 2002

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2 August 2017

published in

Trends in Cell Biology

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2 August 2017

volume

12

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2 August 2017

issue

1

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2 August 2017

page(s)

28-36

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Principles of CDK regulation

2 August 2017

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Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons

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Cyclin-dependent kinase 5 promotes insulin exocytosis.

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7 January 2021

Regulation of exocytosis by cyclin-dependent kinase 5 via phosphorylation of Munc18

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7 January 2021

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Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration

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7 January 2021

Neurotoxicity induces cleavage of p35 to p25 by calpain

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7 January 2021

p35, the neuronal-specific activator of cyclin-dependent kinase 5 (Cdk5) is degraded by the ubiquitin-proteasome pathway

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7 January 2021

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7 January 2021

Accumulation of cyclin-dependent kinase 5 (cdk5) in neurons with early stages of Alzheimer's disease neurofibrillary degeneration

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7 January 2021

Abnormal Alzheimer-like phosphorylation of tau-protein by cyclin-dependent kinases cdk2 and cdk5

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7 January 2021

Hyperphosphorylated tau and neurofilament and cytoskeletal disruptions in mice overexpressing human p25, an activator of cdk5

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

Extra axonal neurofilaments do not exacerbate disease caused by mutant Cu,Zn superoxide dismutase.

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7 January 2021

Deregulation of Cdk5 in a mouse model of ALS: toxicity alleviated by perikaryal neurofilament inclusions

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7 January 2021

Overexpression of tau protein inhibits kinesin-dependent trafficking of vesicles, mitochondria, and endoplasmic reticulum: implications for Alzheimer's disease

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7 January 2021

Axonal transport of amyloid precursor protein is mediated by direct binding to the kinesin light chain subunit of kinesin-I

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7 January 2021

Slowing of axonal transport is a very early event in the toxicity of ALS-linked SOD1 mutants to motor neurons

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7 January 2021

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7 January 2021

Region-specific expression of cyclin-dependent kinase 5 (cdk5) and its activators, p35 and p39, in the developing and adult rat central nervous system

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7 January 2021

Nuclear migration, nucleokinesis and lissencephaly

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7 January 2021

Cytoplasmic dynein and dynactin in cell division and intracellular transport

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7 January 2021

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Identifiers

DOI

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2 August 2017

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