Inhibition of protein geranylgeranylation induces apoptosis in synovial fibroblasts (Q34538139)

2 August 2017

Inhibition of protein geranylgeranylation induces apoptosis in synovial fibroblasts (English)

1 reference

2 August 2017

Alison M Connor

1

1 reference

2 August 2017

Stuart Berger

series ordinal

2

1 reference

2 August 2017

Aru Narendran

series ordinal

3

1 reference

2 August 2017

Edward C Keystone

series ordinal

4

1 reference

2 August 2017

1 January 2006

1 reference

Arthritis Research and Therapy

2 August 2017

1 reference

2 August 2017

8

1 reference

2 August 2017

4

1 reference

2 August 2017

R94

1 reference

https://scigraph.springernature.com/pub.10.1186/ar1968

2 August 2017

0 references

cites work

Rac1 modulates sphingosine 1-phosphate-mediated activation of phosphoinositide 3-kinase/Akt signaling pathways in vascular endothelial cells

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Anti-TNF therapy: where have we got to in 2005?

7 July 2018

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Intermolecular differences of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors contribute to distinct pharmacologic and pleiotropic actions

7 July 2018

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Role of the isoprenoid pathway in ras transforming activity, cytoskeleton organization, cell proliferation and apoptosis.

7 July 2018

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The fibroblast-like synovial cell in rheumatoid arthritis: a key player in inflammation and joint destruction.

7 July 2018

1 reference

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Gene transfer of tissue inhibitor of metalloproteinases-3 reverses the inhibitory effects of TNF-alpha on Fas-induced apoptosis in rheumatoid arthritis synovial fibroblasts

7 July 2018

1 reference

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Molecular mechanisms of TNF-alpha-induced apoptosis in aging human T cell subsets

7 July 2018

1 reference

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Chemical, pharmacokinetic and pharmacodynamic properties of statins: an update

7 July 2018

1 reference

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The origin of the statins. 2004

7 July 2018

1 reference

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Trial of Atorvastatin in Rheumatoid Arthritis (TARA): double-blind, randomised placebo-controlled trial

7 July 2018

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IL-17 induces production of IL-6 and IL-8 in rheumatoid arthritis synovial fibroblasts via NF-kappaB- and PI3-kinase/Akt-dependent pathways

7 July 2018

1 reference

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Protein geranylgeranylation is critical for the regulation of survival and proliferation of lymphoma tumor cells

7 July 2018

1 reference

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Evolving concepts of rheumatoid arthritis

7 July 2018

1 reference

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A question of transformation: the synovial fibroblast in rheumatoid arthritis

7 July 2018

1 reference

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Anti-inflammatory and immunomodulatory effects of statins.

7 July 2018

1 reference

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Apoptosis as a therapeutic tool in rheumatoid arthritis

7 July 2018

1 reference

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Immunomodulatory effects of statins: mechanisms and potential impact on arteriosclerosis

7 July 2018

1 reference

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Rac1 and RhoG promote cell survival by the activation of PI3K and Akt, independently of their ability to stimulate JNK and NF-kappaB

7 July 2018

1 reference

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A novel role for interleukin-18 in adhesion molecule induction through NF kappa B and phosphatidylinositol (PI) 3-kinase-dependent signal transduction pathways

7 July 2018

1 reference

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Anti-apoptotic function of Rac in hematopoietic cells.

7 July 2018

1 reference

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Novel salvage pathway utilizing farnesol and geranylgeraniol for protein isoprenylation

7 July 2018

1 reference

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Rheumatoid arthritis synovial fibroblast and U937 macrophage/monocyte cell line interaction in cartilage degradation

7 July 2018

1 reference

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Regulation of cellular signalling by fatty acid acylation and prenylation of signal transduction proteins

7 July 2018

1 reference

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Inhibition of isoprenoid biosynthesis induces apoptosis in human promyelocytic HL-60 cells.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1779395

Phase separation of integral membrane proteins in Triton X-114 solution

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1779395

Regulation of the mevalonate pathway

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1779395

An improved colorimetric assay for cell proliferation and viability utilizing the tetrazolium salt XTT.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1779395

Assessment of the efficacy of different statins in murine collagen-induced arthritis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1779395

Inhibition of geranylgeranylation mediates the effects of 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase inhibitors on microglia

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1779395

Simvastatin reduces human atrial myofibroblast proliferation independently of cholesterol lowering via inhibition of RhoA.

27 October 2018

1 reference

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Akt is an endogenous inhibitor toward tumor necrosis factor-related apoptosis inducing ligand-mediated apoptosis in rheumatoid synovial cells

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1779395

A novel anti-inflammatory role for simvastatin in inflammatory arthritis

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1779395

Simvastatin induces activation of the serine-threonine protein kinase AKT and increases survival of isolated human pancreatic islets

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1779395

Necessary role of phosphatidylinositol 3-kinase in transforming growth factor beta-mediated activation of Akt in normal and rheumatoid arthritis synovial fibroblasts

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1779395

Regulation of TNF-alpha-mediated hyperplasia through TNF receptors, TRAFs, and NF-kappaB in synoviocytes obtained from patients with rheumatoid arthritis.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1779395

Regulation of tumor necrosis factor alpha-mediated apoptosis of rheumatoid arthritis synovial fibroblasts by the protein kinase Akt.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1779395

Cerivastatin triggers tumor-specific apoptosis with higher efficacy than lovastatin.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1779395

Rac1 inhibits TNF-alpha-induced endothelial cell apoptosis: dual regulation by reactive oxygen species

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1779395

Gene therapy that inhibits nuclear translocation of nuclear factor kappaB results in tumor necrosis factor alpha-induced apoptosis of human synovial fibroblasts

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1779395

Lovastatin induces fibroblast apoptosis in vitro and in vivo. A possible therapy for fibroproliferative disorders.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1779395

Simultaneous inhibition of Rac1 and IKK pathways sensitizes lung cancer cells to TNFalpha-mediated apoptosis

27 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16774691

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase and Isoprenylation Inhibitors Induce Apoptosis of Vascular Smooth Muscle Cells in Culture

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16774691

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/AR1968

1 reference

Dimensions Publication ID

2 August 2017

0 references

1 reference

2 August 2017

1 reference