Modeling a genetic risk for schizophrenia in iPSCs and mice reveals neural stem cell deficits associated with adherens junctions and polarity (Q34540416)

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English	Modeling a genetic risk for schizophrenia in iPSCs and mice reveals neural stem cell deficits associated with adherens junctions and polarity	scientific article

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2 August 2017

Modeling a genetic risk for schizophrenia in iPSCs and mice reveals neural stem cell deficits associated with adherens junctions and polarity (English)

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2 August 2017

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neural stem cell

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Guo-Li Ming

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Hongjun Song

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Daniel R. Weinberger

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Daniel R Weinberger

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Zhexing Wen

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Dan Rujescu

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Judith L. Rapoport

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Judith L Rapoport

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David St Clair

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Kimberly M Christian

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Kimberly M Christian

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Joo Heon Shin

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Nam-Shik Kim

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Georgia Makri

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Ki-Jun Yoon

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Ha Nam Nguyen

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Gianluca Ursini

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Fengyu Zhang

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David Nauen

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Youngbin Park

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Raeeun Chung

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Eva Pekle

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Ce Zhang

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Maxwell Towe

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Syed Mohammed Qasim Hussaini

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Yohan Lee

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Joel E Kleinman

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Thomas M Hyde

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Gregory Krauss

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1 July 2014

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79-91

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2 August 2017

Patches of disorganization in the neocortex of children with autism

1 reference

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CNVs conferring risk of autism or schizophrenia affect cognition in controls

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Copy number variants are frequent in genetic generalized epilepsy with intellectual disability

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DISC1 genetics, biology and psychiatric illness

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Scratch regulates neuronal migration onset via an epithelial-mesenchymal transition-like mechanism

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Haploinsufficiency of Cyfip1 produces fragile X-like phenotypes in mice

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Astrocytes generated from patient induced pluripotent stem cells recapitulate features of Huntington's disease patient cells

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Abnormal intracellular accumulation and extracellular Aβ deposition in idiopathic and Dup15q11.2-q13 autism spectrum disorders

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Foxp-mediated suppression of N-cadherin regulates neuroepithelial character and progenitor maintenance in the CNS.

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CNVs: harbingers of a rare variant revolution in psychiatric genetics

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7 July 2018

Rare CNVs and tag SNPs at 15q11.2 are associated with schizophrenia in the Han Chinese population

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Human cerebral cortex development from pluripotent stem cells to functional excitatory synapses

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7 July 2018

CYFIP dependent actin remodeling controls specific aspects of Drosophila eye morphogenesis.

1 reference

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7 July 2018

A copy number variation morbidity map of developmental delay

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7 July 2018

Normalization of cortical gray matter deficits in nonpsychotic siblings of patients with childhood-onset schizophrenia

1 reference

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7 July 2018

Rapid induction and long-term self-renewal of primitive neural precursors from human embryonic stem cells by small molecule inhibitors

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7 July 2018

Essential role for Abi1 in embryonic survival and WAVE2 complex integrity

1 reference

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7 July 2018

Integration-free induced pluripotent stem cells derived from schizophrenia patients with a DISC1 mutation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237009

7 July 2018

Confirmed rare copy number variants implicate novel genes in schizophrenia

1 reference

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7 July 2018

A co-segregating microduplication of chromosome 15q11.2 pinpoints two risk genes for autism spectrum disorder

1 reference

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7 July 2018

Recurrent microdeletions at 15q11.2 and 16p13.11 predispose to idiopathic generalized epilepsies

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7 July 2018

beta1 integrin maintains integrity of the embryonic neocortical stem cell niche

1 reference

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7 July 2018

Advances in autism

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The glial nature of embryonic and adult neural stem cells

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7 July 2018

Support for the involvement of large copy number variants in the pathogenesis of schizophrenia

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The fragile X syndrome protein represses activity-dependent translation through CYFIP1, a new 4E-BP

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Large recurrent microdeletions associated with schizophrenia

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7 July 2018

Rare chromosomal deletions and duplications increase risk of schizophrenia

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7 July 2018

Numb and Numbl are required for maintenance of cadherin-based adhesion and polarity of neural progenitors

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Genome-wide expression profiling of lymphoblastoid cell lines distinguishes different forms of autism and reveals shared pathways

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Spindle regulation in neural precursors of flies and mammals

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Pax6, Tbr2, and Tbr1 are expressed sequentially by radial glia, intermediate progenitor cells, and postmitotic neurons in developing neocortex

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Sra-1 and Nap1 link Rac to actin assembly driving lamellipodia formation.

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Abi, Sra1, and Kette control the stability and localization of SCAR/WAVE to regulate the formation of actin-based protrusions

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Human brain malformations and their lessons for neuronal migration

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Neurodevelopmental abnormalities in schizophrenia: insights from neuropathology.

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12 December 2020

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10.1016/J.STEM.2014.05.003

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