Medicarpin, a legume phytoalexin sensitizes myeloid leukemia cells to TRAIL-induced apoptosis through the induction of DR5 and activation of the ROS-JNK-CHOP pathway (Q34541614)

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English	Medicarpin, a legume phytoalexin sensitizes myeloid leukemia cells to TRAIL-induced apoptosis through the induction of DR5 and activation of the ROS-JNK-CHOP pathway	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

2 August 2017

Medicarpin, a legume phytoalexin sensitizes myeloid leukemia cells to TRAIL-induced apoptosis through the induction of DR5 and activation of the ROS-JNK-CHOP pathway (English)

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Europe PubMed Central

PubMed publication ID

2 August 2017

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based on heuristic

inferred from title

myeloid leukemia

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based on heuristic

inferred from title

author name string

R Trivedi

1

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

R Maurya

2

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Europe PubMed Central

PubMed publication ID

2 August 2017

D P Mishra

3

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Europe PubMed Central

PubMed publication ID

2 August 2017

publication date

16 October 2014

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Europe PubMed Central

PubMed publication ID

2 August 2017

Cell Death and Disease

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Europe PubMed Central

PubMed publication ID

2 August 2017

5

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Europe PubMed Central

PubMed publication ID

2 August 2017

e1465

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Europe PubMed Central

PubMed publication ID

2 August 2017

copyright license

Creative Commons Attribution 4.0 International

1 October 2014

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April 2022 Public Data File from Crossref

copyright status

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(6)-Gingerolinduced myeloid leukemia cell death is initiated by reactive oxygen species and activation of miR-27b expression.

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7 July 2018

The transcription factor Wilms tumor 1 confers resistance in myeloid leukemia cells against the proapoptotic therapeutic agent TRAIL (tumor necrosis factor α-related apoptosis-inducing ligand) by regulating the antiapoptotic protein Bcl-xL

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7 July 2018

Triptolide sensitizes TRAIL-induced apoptosis in prostate cancer cells via p53-mediated DR5 up-regulation

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7 July 2018

Phytoalexins in cancer prevention

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7 July 2018

Advances in the treatment of chronic myeloid leukemia

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7 July 2018

Ursolic acid, a pentacyclin triterpene, potentiates TRAIL-induced apoptosis through p53-independent up-regulation of death receptors: evidence for the role of reactive oxygen species and JNK

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Centchroman inhibits proliferation of head and neck cancer cells through the modulation of PI3K/mTOR pathway

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7 July 2018

Gossypol induces death receptor-5 through activation of the ROS-ERK-CHOP pathway and sensitizes colon cancer cells to TRAIL

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7 July 2018

Garcinol potentiates TRAIL-induced apoptosis through modulation of death receptors and antiapoptotic proteins

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7 July 2018

Zerumbone enhances TRAIL-induced apoptosis through the induction of death receptors in human colon cancer cells: Evidence for an essential role of reactive oxygen species.

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7 July 2018

Rottlerin induces apoptosis via death receptor 5 (DR5) upregulation through CHOP-dependent and PKC delta-independent mechanism in human malignant tumor cells

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7 July 2018

Coupling of endoplasmic reticulum stress to CDDO-Me-induced up-regulation of death receptor 5 via a CHOP-dependent mechanism involving JNK activation

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7 July 2018

Reactive oxygen species mediate oridonin-induced HepG2 apoptosis through p53, MAPK, and mitochondrial signaling pathways

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7 July 2018

Andrographolide sensitizes cancer cells to TRAIL-induced apoptosis via p53-mediated death receptor 4 up-regulation.

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7 July 2018

To kill a tumor cell: the potential of proapoptotic receptor agonists

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7 July 2018

Inhibiting survivin expression enhances TRAIL-induced tumoricidal activity in human hepatocellular carcinoma via cell cycle arrest

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7 July 2018

Tunicamycin sensitizes human melanoma cells to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by up-regulation of TRAIL-R2 via the unfolded protein response

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TRAIL receptor-mediated JNK activation and Bim phosphorylation critically regulate Fas-mediated liver damage and lethality.

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7 July 2018

Survivin inhibits apoptosis induced by TRAIL, and the ratio between survivin and TRAIL receptors is predictive of recurrent disease in neuroblastoma

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7 July 2018

Sulforaphane sensitizes tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-resistant hepatoma cells to TRAIL-induced apoptosis through reactive oxygen species-mediated up-regulation of DR5.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237253

7 July 2018

Endoplasmic reticulum quality control and apoptosis

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7 July 2018

Mechanisms of resistance to TRAIL-induced apoptosis in cancer

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7 July 2018

Rottlerin sensitizes glioma cells to TRAIL-induced apoptosis by inhibition of Cdc2 and the subsequent downregulation of survivin and XIAP.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237253

7 July 2018

CHOP is involved in endoplasmic reticulum stress-induced apoptosis by enhancing DR5 expression in human carcinoma cells

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237253

7 July 2018

X-linked inhibitor of apoptosis protein (XIAP) is a nonredundant modulator of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis in human cancer cells

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7 July 2018

Promoter of TRAIL-R2 gene

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7 July 2018

Mitogen-activated protein kinase/extracellular signal-regulated kinase signaling in activated T cells abrogates TRAIL-induced apoptosis upstream of the mitochondrial amplification loop and caspase-8

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Promoter structure and transcription initiation sites of the human death receptor 5/TRAIL-R2 gene

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TRAIL receptor-2 signals apoptosis through FADD and caspase-8

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Molecular cloning and functional analysis of the mouse homologue of the KILLER/DR5 tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) death receptor.

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7 July 2018

Apoptosis control by death and decoy receptors

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7 July 2018

Inhibition of nuclear factor kappaB activation attenuates apoptosis resistance in lymphoid cells

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7 July 2018

Reactive oxygen species and programmed cell death

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7 July 2018

Medicarpin, a legume phytoalexin, stimulates osteoblast differentiation and promotes peak bone mass achievement in rats: evidence for estrogen receptor β-mediated osteogenic action of medicarpin.

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Induction of apoptosis by pterocarpans from Platymiscium floribundum in HL-60 human leukemia cells.

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Downregulation of Bcl-2, FLIP or IAPs (XIAP and survivin) by siRNAs sensitizes resistant melanoma cells to Apo2L/TRAIL-induced apoptosis

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The proteasome inhibitor PS-341 sensitizes neoplastic cells to TRAIL-mediated apoptosis by reducing levels of c-FLIP.

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Medicarpin inhibits osteoclastogenesis and has nonestrogenic bone conserving effect in ovariectomized mice

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15-Deoxy-Δ12,14-prostaglandin J2 induces apoptosis through activation of the CHOP gene in HeLa cells

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TRAIL decoy receptors mediate resistance of acute myeloid leukemia cells to TRAIL.

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Involvement of proapoptotic molecules Bax and Bak in tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced mitochondrial disruption and apoptosis: differential regulation of cytochrome c and Smac/DIABLO release

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CCAAT/enhancer binding protein homologous protein-dependent death receptor 5 induction and ubiquitin/proteasome-mediated cellular FLICE-inhibitory protein down-regulation contribute to enhancement of tumor necrosis factor-related apoptosis-inducing

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α-Tocopheryl succinate induces DR4 and DR5 expression by a p53-dependent route: Implication for sensitisation of resistant cancer cells to TRAIL apoptosis

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10.1038/CDDIS.2014.429

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Europe PubMed Central

PubMed publication ID

2 August 2017

release_fv7ffjx7c5d43ohta5bhkdoj2q

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https://api.fatcat.wiki/v0/release/fv7ffjx7c5d43ohta5bhkdoj2q

24 November 2022

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Europe PubMed Central

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2 August 2017

PubMed publication ID

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Europe PubMed Central

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