TRAIL receptor-mediated JNK activation and Bim phosphorylation critically regulate Fas-mediated liver damage and lethality. (Q35009467)

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29 December 2019

title

TRAIL receptor-mediated JNK activation and Bim phosphorylation critically regulate Fas-mediated liver damage and lethality (English)

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29 December 2019

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9

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Pascal Schneider

10

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29 December 2019

author name string

Nadia Corazza

1

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Sabine Jakob

2

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29 December 2019

Corinne Schaer

3

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29 December 2019

Steffen Frese

4

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29 December 2019

Adrian Keogh

5

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29 December 2019

Deborah Stroka

6

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Daniela Kassahn

7

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Ralph Torgler

8

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Thomas Brunner

11

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29 December 2019

language of work or name

English

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publication date

1 September 2006

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Journal of Clinical Investigation

29 December 2019

published in

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volume

116

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issue

9

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page(s)

2493-2499

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Caspase cleavage of BimEL triggers a positive feedback amplification of apoptotic signaling

29 December 2019

cites work

1 reference

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Critical roles of TRAIL in hepatic cell death and hepatic inflammation.

8 July 2018

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TRAIL and apoptosis induction by TNF-family death receptors.

8 July 2018

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Fas (CD95/Apo-1) ligand regulation in T cell homeostasis, cell-mediated cytotoxicity and immune pathology

8 July 2018

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Apo2L/TRAIL and its death and decoy receptors

8 July 2018

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Two adjacent trimeric Fas ligands are required for Fas signaling and formation of a death-inducing signaling complex

8 July 2018

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TRAIL-induced apoptosis requires Bax-dependent mitochondrial release of Smac/DIABLO.

8 July 2018

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SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase

8 July 2018

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Proliferation, cell cycle and apoptosis in cancer

8 July 2018

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Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) contributes to interferon gamma-dependent natural killer cell protection from tumor metastasis

8 July 2018

1 reference

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The death domain kinase RIP is essential for TRAIL (Apo2L)-induced activation of IkappaB kinase and c-Jun N-terminal kinase

8 July 2018

1 reference

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Fas and Fas ligand in gut and liver

8 July 2018

1 reference

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8 July 2018

The Hallmarks of Cancer

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Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity

8 July 2018

1 reference

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Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis

8 July 2018

1 reference

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Safety and antitumor activity of recombinant soluble Apo2 ligand

8 July 2018

1 reference

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The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex

8 July 2018

1 reference

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Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo.

8 July 2018

1 reference

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Modulation of life and death by the TNF receptor superfamily

8 July 2018

1 reference

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Caspase cleaved BID targets mitochondria and is required for cytochrome c release, while BCL-XL prevents this release but not tumor necrosis factor-R1/Fas death

8 July 2018

1 reference

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Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

8 July 2018

1 reference

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Fas ligand- mediated killing by intestinal intraepithelial lymphocytes. Participation in intestinal graft-versus-host disease

8 July 2018

1 reference

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Lethal effect of the anti-Fas antibody in mice

8 July 2018

1 reference

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Tissue distribution of the death ligand TRAIL and its receptors.

8 July 2018

1 reference

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JNK-mediated BIM phosphorylation potentiates BAX-dependent apoptosis

26 October 2018

1 reference

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Increased susceptibility to tumor initiation and metastasis in TNF-related apoptosis-inducing ligand-deficient mice

26 October 2018

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Enhancement of Apo2L/TRAIL (tumor necrosis factor-related apoptosis-inducing ligand)-induced apoptosis in non-small cell lung cancer cell lines by chemotherapeutic agents without correlation to the expression level of cellular protease caspase-8 inh

26 October 2018

1 reference

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TRAIL and immunity: more than a license to kill tumor cells

26 October 2018

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12 December 2020

Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand

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12 December 2020

Involvement of tumor necrosis factor-related apoptosis-inducing ligand in surveillance of tumor metastasis by liver natural killer cells

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12 December 2020

Differential hepatocyte toxicity of recombinant Apo2L/TRAIL versions

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12 December 2020

Fc gamma Rs modulate cytotoxicity of anti-Fas antibodies: implications for agonistic antibody-based therapeutics

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12 December 2020

Local Fas/APO-1 (CD95) ligand-mediated tumor cell killing in vivo

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12 December 2020

Essential roles of the Fas ligand in the development of hepatitis

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12 December 2020

Contribution of Fas ligand to T cell-mediated hepatic injury in mice

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12 December 2020

In vivo evidence for a functional role of both tumor necrosis factor (TNF) receptors and transmembrane TNF in experimental hepatitis

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12 December 2020

TRAIL and thymocyte apoptosis: not so deadly?

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12 December 2020

Identifiers

DOI

10.1172/JCI27726

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16955144%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

1 reference

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29 December 2019

PubMed publication ID

16955144

1 reference