EXP-1 is an excitatory GABA-gated cation channel (Q34542555)

2 August 2017

EXP-1 is an excitatory GABA-gated cation channel (English)

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Gamma-aminobutyric acid receptor exp-1 CELE_H35N03.1

2 August 2017

1 reference

GOA release 2020-03-11

author name string

Asim A Beg

series ordinal

1

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PubMed ID

14555952

2 August 2017

Erik M Jorgensen

series ordinal

2

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PubMed ID

14555952

2 August 2017

language of work or name

English

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publication date

12 October 2003

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2 August 2017

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2 August 2017

6

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2 August 2017

11

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2 August 2017

1145-1152

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https://scigraph.springernature.com/pub.10.1038/nn1136

2 August 2017

0 references

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GABA(A) receptor beta 2 Tyr97 and Leu99 line the GABA-binding site. Insights into mechanisms of agonist and antagonist actions

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Identification of acetylcholine receptor channel-lining residues in the entire M2 segment of the alpha subunit.

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Mutations in the channel domain of a neuronal nicotinic receptor convert ion selectivity from cationic to anionic.

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Ion currents of Xenopus laevis oocytes: state of the art.

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A single amino acid in gamma-aminobutyric acid rho 1 receptors affects competitive and noncompetitive components of picrotoxin inhibition

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Cloning of a gamma-aminobutyric acid type C receptor subunit in rat retina with a methionine residue critical for picrotoxinin channel block

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Pharmacologic characteristics of excitatory gamma-amino-butyric acid (GABA) receptors in a snail neuron

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Rings of negatively charged amino acids determine the acetylcholine receptor channel conductance

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The permeation pathway of neurotransmitter-gated ion channels

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The location of the gate in the acetylcholine receptor channel.

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Identification of channel-lining residues in the M2 membrane-spanning segment of the GABA(A) receptor alpha1 subunit

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Cation-selective mutations in the M2 domain of the inhibitory glycine receptor channel reveal determinants of ion-charge selectivity

21 January 2018

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Conversion of the ion selectivity of the 5-HT(3a) receptor from cationic to anionic reveals a conserved feature of the ligand-gated ion channel superfamily

21 January 2018

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M2 pore mutations convert the glycine receptor channel from being anion- to cation-selective

21 January 2018

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Single channel analysis of conductance and rectification in cation-selective, mutant glycine receptor channels

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Evolutionary history of the ligand-gated ion-channel superfamily of receptors

21 January 2018

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Arginine residue 120 of the human GABAA receptor alpha 1, subunit is essential for GABA binding and chloride ion current gating

21 January 2018

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GABAA receptor needs two homologous domains of the beta-subunit for activation by GABA but not by pentobarbital.

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7 January 2021

Long-lasting GABA-mediated depolarization evoked by high-frequency stimulation in pyramidal neurons of rat hippocampal slice is attributable to a network-driven, bicarbonate-dependent K+ transient.

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7 January 2021

Ionic mechanisms of neuronal excitation by inhibitory GABAA receptors

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7 January 2021

Cl- accumulation does not account for the depolarizing phase of the synaptic GABA response in hippocampal pyramidal cells

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7 January 2021

GABAergic excitatory synapses and electrical coupling sustain prolonged discharges in the prey capture neural network of Clione limacina.

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7 January 2021

The Caenorhabditis elegans unc-49 locus encodes multiple subunits of a heteromultimeric GABA receptor.

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7 January 2021

Factors that determine connectivity in the nervous system of Caenorhabditis elegans

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7 January 2021

The Caenorhabditis elegans gene unc-25 encodes glutamic acid decarboxylase and is required for synaptic transmission but not synaptic development.

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7 January 2021

Reversal of a muscle response to GABA during C. elegans male development.

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7 January 2021

Structure and dynamics of the GABA binding pocket: A narrowing cleft that constricts during activation.

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7 January 2021

Decreased agonist affinity and chloride conductance of mutant glycine receptors associated with human hereditary hyperekplexia

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7 January 2021

Point mutations affecting antagonist affinity and agonist dependent gating of GABAA receptor channels.

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7 January 2021

Mapping the agonist binding site of the GABAA receptor: evidence for a beta-strand.

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7 January 2021

Identifiers

DOI

10.1038/NN1136

1 reference

2 August 2017

1 reference

PubMed ID

14555952