Polycystic kidney disease: cell division without a c(l)ue? (Q34544069)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16816842%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

review article

1 reference

title

Polycystic kidney disease: cell division without a c(l)ue? (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16816842%20AND%20SRC:MED&resulttype=core&format=json

polycystic kidney disease

26 December 2019

main subject

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1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16816842%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

author name string

Walz G

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16816842%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

language of work or name

English

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publication date

28 June 2006

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26 December 2019

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16816842%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

volume

70

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16816842%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

page(s)

854-864

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26 December 2019

issue

5

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https://scigraph.springernature.com/pub.10.1038/sj.ki.5001534

26 December 2019

exact match

0 references

cites work

Polycystic kidney disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

Role of polycystins in renal tubulogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

The genetics and physiology of polycystic kidney disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

Polycystins: from mechanosensation to gene regulation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

Nephrocystin-5, a ciliary IQ domain protein, is mutated in Senior-Loken syndrome and interacts with RPGR and calmodulin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

Polycystic kidney disease: new understanding in the pathogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

Ciliary proteins and exencephaly.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

Mutations in INVS encoding inversin cause nephronophthisis type 2, linking renal cystic disease to the function of primary cilia and left-right axis determination

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

Abnormal polarization of EGF receptors and autocrine stimulation of cyst epithelial growth in human ADPKD

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

The polycystic kidney disease 1 gene product mediates protein kinase C alpha-dependent and c-Jun N-terminal kinase-dependent activation of the transcription factor AP-1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

The polycystic kidney disease-1 protein, polycystin-1, binds and activates heterotrimeric G-proteins in vitro.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

Polycystin-1 activation of c-Jun N-terminal kinase and AP-1 is mediated by heterotrimeric G proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

Mechanical stimuli induce cleavage and nuclear translocation of the polycystin-1 C terminus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

The polycystin-1 C-terminal fragment triggers branching morphogenesis and migration of tubular kidney epithelial cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

PKD1 induces p21(waf1) and regulation of the cell cycle via direct activation of the JAK-STAT signaling pathway in a process requiring PKD2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

Pkd1 regulates immortalized proliferation of renal tubular epithelial cells through p53 induction and JNK activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

Apoptosis and loss of renal tissue in polycystic kidney diseases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

Dysregulation of the TSC-mTOR pathway in human disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

Rapamycin markedly slows disease progression in a rat model of polycystic kidney disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

Inhibition of mTOR with sirolimus slows disease progression in Han:SPRD rats with autosomal dominant polycystic kidney disease (ADPKD).

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

Lethality of Drosophila lacking TSC tumor suppressor function rescued by reducing dS6K signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

Akt regulates growth by directly phosphorylating Tsc2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

An incredible decade for the primary cilium: a look at a once-forgotten organelle

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

Intraflagellar transport and cilia-dependent renal disease: the ciliary hypothesis of polycystic kidney disease.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

Randomization of left-right asymmetry due to loss of nodal cilia generating leftward flow of extraembryonic fluid in mice lacking KIF3B motor protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

Intraflagellar transport.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

Intraflagellar Transport

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

Chlamydomonas IFT88 and its mouse homologue, polycystic kidney disease gene tg737, are required for assembly of cilia and flagella

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

An autosomal recessive polycystic kidney disease gene homolog is involved in intraflagellar transport in C. elegans ciliated sensory neurons

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

The Caenorhabditis elegans autosomal dominant polycystic kidney disease gene homologs lov-1 and pkd-2 act in the same pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

A polycystic kidney-disease gene homologue required for male mating behaviour in C. elegans

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

Sensory regulation of male mating behavior in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

The polycystic kidney disease proteins, polycystin-1, polycystin-2, polaris, and cystin, are co-localized in renal cilia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

Cilia and centrosomes: a unifying pathogenic concept for cystic kidney disease?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

A genetic screen in zebrafish identifies cilia genes as a principal cause of cystic kidney

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

Kidney-specific inactivation of the KIF3A subunit of kinesin-II inhibits renal ciliogenesis and produces polycystic kidney disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

Cilia-driven fluid flow in the zebrafish pronephros, brain and Kupffer's vesicle is required for normal organogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

Cilia in the human kidney

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

PDGFRalphaalpha signaling is regulated through the primary cilium in fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

Vertebrate Smoothened functions at the primary cilium

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

Gli2 and Gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

Cilia and the cell cycle?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

Expression of primary cilia in mammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

The subcellular organization of Madin-Darby canine kidney cells during the formation of a polarized epithelium

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

Proteomic characterization of the human centrosome by protein correlation profiling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

Requirement of Cdk2-cyclin E activity for repeated centrosome reproduction in Xenopus egg extracts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

Cyclin-dependent kinase control of centrosome duplication

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

Cellular deflagellation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

Mutations in a NIMA-related kinase gene, Nek1, cause pleiotropic effects including a progressive polycystic kidney disease in mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

A defect in a novel Nek-family kinase causes cystic kidney disease in the mouse and in zebrafish

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

Expression analyses and interaction with the anaphase promoting complex protein Apc2 suggest a role for inversin in primary cilia and involvement in the cell cycle

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

The Invs gene encodes a microtubule-associated protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

Inversin forms a complex with catenins and N-cadherin in polarized epithelial cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

Rapid microtubule-independent dynamics of Cdc20 at kinetochores and centrosomes in mammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

The roles of Fzy/Cdc20 and Fzr/Cdh1 in regulating the destruction of cyclin B in space and time

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

APC/C-mediated destruction of the centrosomal kinase Nek2A occurs in early mitosis and depends upon a cyclin A-type D-box

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

Basal body dysfunction is a likely cause of pleiotropic Bardet-Biedl syndrome

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

Epithelial transformation of metanephric mesenchyme in the developing kidney regulated by Wnt-4

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

Wnt9b plays a central role in the regulation of mesenchymal to epithelial transitions underlying organogenesis of the mammalian urogenital system

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

Wnt11 and Ret/Gdnf pathways cooperate in regulating ureteric branching during metanephric kidney development.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

Convergence of Wnt, beta-catenin, and cadherin pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

Early development of polycystic kidney disease in transgenic mice expressing an activated mutant of the beta-catenin gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signaling pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

The ankyrin repeat protein Diversin recruits Casein kinase Iepsilon to the beta-catenin degradation complex and acts in both canonical Wnt and Wnt/JNK signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

Mapping Wnt/beta-catenin signaling during mouse development and in colorectal tumors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

Planar cell polarization: an emerging model points in the right direction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

Linking cilia to Wnts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

Prickle mediates feedback amplification to generate asymmetric planar cell polarity signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

Polarized transport of Frizzled along the planar microtubule arrays in Drosophila wing epithelium.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

Ciliogenesis defects in embryos lacking inturned or fuzzy function are associated with failure of planar cell polarity and Hedgehog signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

Triallelic inheritance in Bardet-Biedl syndrome, a Mendelian recessive disorder

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

Lifting the lid on Pandora's box: the Bardet-Biedl syndrome

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

Comparative genomics identifies a flagellar and basal body proteome that includes the BBS5 human disease gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

Decoding cilia function: defining specialized genes required for compartmentalized cilia biogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

The Bardet-Biedl protein BBS4 targets cargo to the pericentriolar region and is required for microtubule anchoring and cell cycle progression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

Antenatal presentation of Bardet-Biedl syndrome may mimic Meckel syndrome

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

MKS1, encoding a component of the flagellar apparatus basal body proteome, is mutated in Meckel syndrome

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

The transmembrane protein meckelin (MKS3) is mutated in Meckel-Gruber syndrome and the wpk rat.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

Centrosome localization determines neuronal polarity.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

The centrosome in vertebrates: more than a microtubule-organizing center

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

Centrosomes direct cell polarity independently of microtubule assembly in C. elegans embryos

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

Polarity proteins control ciliogenesis via kinesin motor interactions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

The orientation of cell divisions determines the shape of Drosophila organs.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

Frizzled signalling controls orientation of asymmetric sense organ precursor cell divisions in Drosophila.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

Planar cell polarity signalling controls cell division orientation during zebrafish gastrulation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

Planar cell polarity signalling couples cell division and morphogenesis during neurulation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

Defective planar cell polarity in polycystic kidney disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

A transcriptional network in polycystic kidney disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

Adherens junctions inhibit asymmetric division in the Drosophila epithelium

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

Polycystin-1, the PKD1 gene product, is in a complex containing E-cadherin and the catenins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

The focal adhesion scaffolding protein HEF1 regulates activation of the Aurora-A and Nek2 kinases at the centrosome

1 reference

https://api.crossref.org/works/10.1038%2FSJ.KI.5001534

7 January 2021

Identifiers

DOI

10.1038/SJ.KI.5001534

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16816842%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

26 December 2019

0 references

1 reference