Resveratrol is a peroxidase-mediated inactivator of COX-1 but not COX-2: a mechanistic approach to the design of COX-1 selective agents. (Q34546310)

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25 December 2019

title

Resveratrol is a peroxidase-mediated inactivator of COX-1 but not COX-2: a mechanistic approach to the design of COX-1 selective agents (English)

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25 December 2019

2

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25 December 2019

Trevor M Penning

series ordinal

4

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25 December 2019

author name string

Lawrence M Szewczuk

series ordinal

1

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25 December 2019

Lucia A Stivala

series ordinal

3

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25 December 2019

language of work or name

English

0 references

publication date

12 March 2004

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Journal of Biological Chemistry

25 December 2019

published in

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25 December 2019

volume

279

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25 December 2019

issue

21

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25 December 2019

page(s)

22727-22737

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The red wine phenolics trans-resveratrol and quercetin block human platelet aggregation and eicosanoid synthesis: implications for protection against coronary heart disease.

25 December 2019

cites work

1 reference

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Cancer chemopreventive activity of resveratrol, a natural product derived from grapes

21 January 2018

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Paradoxical effects of resveratrol on the two prostaglandin H synthases

21 January 2018

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Detection and Isolation of an Endoperoxide Intermediate in Prostaglandin Biosynthesis

21 January 2018

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Isolation and Structure of Two Prostaglandin Endoperoxides That Cause Platelet Aggregation

21 January 2018

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Mechanism of free radical oxygenation of polyunsaturated fatty acids by cyclooxygenases

21 January 2018

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Thromboxanes: a new group of biologically active compounds derived from prostaglandin endoperoxides

21 January 2018

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An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation

21 January 2018

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Prostacyclin (PGI2) and thromboxane A2 interaction in vivo. Regulation by aspirin and relationship with anti-thrombotic therapy

21 January 2018

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The prostacyclin--thromboxane A2 balance: pathophysiological and therapeutic implications

21 January 2018

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Systemic biosynthesis of prostacyclin by cyclooxygenase (COX)-2: the human pharmacology of a selective inhibitor of COX-2

21 January 2018

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Aspirin as an antiplatelet drug

21 January 2018

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Specific structural determinants are responsible for the antioxidant activity and the cell cycle effects of resveratrol.

21 January 2018

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Expression purification and characterization of recombinant human inducible prostaglandin G/H synthase from baculovirus-infected insect cells

21 January 2018

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Dimerization of resveratrol by the grapevine pathogen Botrytis cinerea

21 January 2018

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Delta-viniferin, a resveratrol dehydrodimer: one of the major stilbenes synthesized by stressed grapevine leaves

21 January 2018

1 reference

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Structural analysis of NSAID binding by prostaglandin H2 synthase: time-dependent and time-independent inhibitors elicit identical enzyme conformations

21 January 2018

1 reference

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Structural basis for selective inhibition of cyclooxygenase-2 by anti-inflammatory agents

21 January 2018

1 reference

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Histidinyl radical formation in the self-peroxidation reaction of bovine copper-zinc superoxide dismutase

21 January 2018

1 reference

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Human cyclooxygenase-2 cDNA

21 January 2018

1 reference

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Platelet-active drugs : the relationships among dose, effectiveness, and side effects

21 January 2018

1 reference

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Resveratrol decreases early signaling events in washed platelets but has little effect on platelet in whole blood

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M314302200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15020596%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

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