Aspartic proteases of Plasmodium falciparum and other parasitic protozoa as drug targets. (Q34548661)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11872398%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

review article

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title

Aspartic proteases of Plasmodium falciparum and other parasitic protozoa as drug targets (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11872398%20AND%20SRC:MED&resulttype=core&format=json

plasmepsin VIII, putative

7 December 2019

main subject

Plasmodium falciparum

0 references

1 reference

10 September 2018

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11 September 2018

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11 September 2018

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11 September 2018

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12 September 2018

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12 September 2018

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12 September 2018

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12 September 2018

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12 September 2018

1 reference

12 September 2018

plasmepsin VI, putative

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24 September 2018

plasmepsin X, putative

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24 September 2018

plasmepsin VII, putative

1 reference

25 September 2018

plasmepsin V, putative

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25 September 2018

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25 September 2018

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25 September 2018

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25 September 2018

histo-aspartic protease

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25 September 2018

plasmepsin IX, putative

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plasmepsin VIII, putative

25 September 2018

1 reference

25 September 2018

plasmepsin VI, putative

1 reference

19 December 2018

plasmepsin X, putative

1 reference

19 December 2018

plasmepsin VI, putative

1 reference

20 December 2018

plasmepsin X, putative

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4

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11872398%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

Jeremy C. Mottram

6

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7 December 2019

author name string

G H Coombs

1

1 reference

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7 December 2019

D E Goldberg

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11872398%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

M Klemba

3

1 reference

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7 December 2019

J Kay

5

1 reference

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7 December 2019

publication date

1 November 2001

1 reference

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7 December 2019

published in

Trends in Parasitology

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7 December 2019

volume

17

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7 December 2019

issue

11

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7 December 2019

page(s)

532-537

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Targeting the HIV-protease in AIDS therapy: a current clinical perspective

7 December 2019

cites work

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7 January 2021

Inhibitors of HIV-1 protease: a major success of structure-assisted drug design

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7 January 2021

Renin inhibition by substituted piperidines: a novel paradigm for the inhibition of monomeric aspartic proteinases?

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7 January 2021

The two sides of enzyme-substrate specificity: lessons from the aspartic proteinases

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7 January 2021

Identification and characterization of falcilysin, a metallopeptidase involved in hemoglobin catabolism within the malaria parasite Plasmodium falciparum

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7 January 2021

Generation of hemoglobin peptides in the acidic digestive vacuole of Plasmodium falciparum implicates peptide transport in amino acid production.

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7 January 2021

Hemoglobin metabolism in the malaria parasite Plasmodium falciparum

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7 January 2021

Molecular characterization and inhibition of a Plasmodium falciparum aspartic hemoglobinase.

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7 January 2021

Expression and characterisation of plasmepsin I from Plasmodium falciparum

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7 January 2021

Order and specificity of the Plasmodium falciparum hemoglobin degradation pathway

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7 January 2021

Effects of foetal haemoglobin on susceptibility of red cells to Plasmodium falciparum

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7 January 2021

Biosynthesis and maturation of the malaria aspartic hemoglobinases plasmepsins I and II.

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7 January 2021

Structure and inhibition of plasmepsin II, a hemoglobin-degrading enzyme from Plasmodium falciparum

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7 January 2021

High level expression and characterisation of Plasmepsin II, an aspartic proteinase from Plasmodium falciparum.

1 reference

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7 January 2021

Kinetic analysis of plasmepsins I and II aspartic proteases of the Plasmodium falciparum digestive vacuole

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7 January 2021

Naturally-occurring and recombinant forms of the aspartic proteinases plasmepsins I and II from the human malaria parasite Plasmodium falciparum

1 reference

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7 January 2021

Active site specificity of plasmepsin II

1 reference

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7 January 2021

Potent, low-molecular-weight non-peptide inhibitors of malarial aspartyl protease plasmepsin II.

1 reference

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7 January 2021

The aspartic proteinase from the rodent parasite Plasmodium berghei as a potential model for plasmepsins from the human malaria parasite, Plasmodium falciparum.

1 reference

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7 January 2021

A distinct member of the aspartic proteinase gene family from the human malaria parasite Plasmodium falciparum

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7 January 2021

Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

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7 January 2021

Expression of Haemonchus contortus pepsinogen in Caenorhabditis elegans.

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7 January 2021

Proteolysis of human hemoglobin by schistosome cathepsin D.

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7 January 2021

Preliminary characterisation of an Onchocerca volvulus aspartic protease

1 reference

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7 January 2021

Acasp, a gene encoding a cathepsin D-like aspartic protease from the hookworm Ancylostoma caninum.

1 reference

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7 January 2021

Gulliver, a long terminal repeat retrotransposon from the genome of the oriental blood fluke Schistosoma japonicum.

1 reference

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7 January 2021

Cloning and characterization of an Eimeria acervulina sporozoite gene homologous to aspartyl proteinases

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7 January 2021

Differential localisation of an Eimeria tenella aspartyl proteinase during the infection process.

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7 January 2021

Characterization of native and recombinant falcipain-2, a principal trophozoite cysteine protease and essential hemoglobinase of Plasmodium falciparum

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7 January 2021

Antimalarial synergy of cysteine and aspartic protease inhibitors

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7 January 2021

Mice deficient for the lysosomal proteinase cathepsin D exhibit progressive atrophy of the intestinal mucosa and profound destruction of lymphoid cells

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7 January 2021

Napsins: new human aspartic proteinases. Distinction between two closely related genes

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7 January 2021

Expression analysis of BACE2 in brain and peripheral tissues

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7 January 2021

Gastric chief cell-specific transcription of the pepsinogen A gene.

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7 January 2021

Identification of the acid proteinase in human seminal fluid as a gastricsin originating in the prostate.

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7 January 2021

Prorenin and renin as separate mediators of tissue and circulating systems

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7 January 2021

10.1016/S1471-4922(01)02037-2

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11872398%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

1 reference