Mdm2 regulates p53 independently of p19(ARF) in homeostatic tissues (Q34551152)

3 August 2017

Mdm2 regulates p53 independently of p19(ARF) in homeostatic tissues (English)

1 reference

3 August 2017

Kathleen A O'Leary

1

1 reference

3 August 2017

Susan M Mendrysa

series ordinal

2

1 reference

3 August 2017

Abram Vaccaro

series ordinal

3

1 reference

3 August 2017

Mary Ellen Perry

series ordinal

4

1 reference

3 August 2017

language of work or name

English

0 references

publication date

1 January 2004

1 reference

Molecular and Cellular Biology

3 August 2017

1 reference

3 August 2017

24

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3 August 2017

1

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3 August 2017

186-191

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Mdm2 haplo-insufficiency profoundly inhibits Myc-induced lymphomagenesis

3 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=303350

Oligomerization of the human ARF tumor suppressor and its response to oxidative stress

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=303350

mdm2 Is critical for inhibition of p53 during lymphopoiesis and the response to ionizing irradiation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=303350

ARF differentially modulates apoptosis induced by E2F1 and Myc.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=303350

p19(ARF) is dispensable for oncogenic stress-induced p53-mediated apoptosis and tumor suppression in vivo

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=303350

Differential requirement for p19ARF in the p53-dependent arrest induced by DNA damage, microtubule disruption, and ribonucleotide depletion

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=303350

The p53 tumor suppressor protein does not regulate expression of its own inhibitor, MDM2, except under conditions of stress

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=303350

INK4a/ARF mutations accelerate lymphomagenesis and promote chemoresistance by disabling p53.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=303350

Disruption of the ARF-Mdm2-p53 tumor suppressor pathway in Myc-induced lymphomagenesis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=303350

The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=303350

Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=303350

ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=303350

Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=303350

Expression of the p16INK4a tumor suppressor versus other INK4 family members during mouse development and aging.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=303350

Regulation of mdm2 expression by p53: alternative promoters produce transcripts with nonidentical translation potential

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=303350

Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=303350

Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=303350

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=303350

INK4a-ARF alterations and p53 mutations in primary and consecutive squamous cell carcinoma of the head and neck.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=303350

Loss of the ARF tumor suppressor reverses premature replicative arrest but not radiation hypersensitivity arising from disabled atm function

27 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/14673154

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Loss of p19ARF enhances the defects of Mdm2 overexpression in the mammary gland

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/14673154

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/MCB.24.1.186-191.2004

1 reference

3 August 2017

1 reference

3 August 2017

1 reference