The nitrosated bile acid DNA lesion O6-carboxymethylguanine is a substrate for the human DNA repair protein O6-methylguanine-DNA methyltransferase (Q34555529)

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English	The nitrosated bile acid DNA lesion O6-carboxymethylguanine is a substrate for the human DNA repair protein O6-methylguanine-DNA methyltransferase	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

3 August 2017

The nitrosated bile acid DNA lesion O6-carboxymethylguanine is a substrate for the human DNA repair protein O6-methylguanine-DNA methyltransferase (English)

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Claire E. Eyers

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Claire E Eyers

7

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author name string

Pattama Senthong

1

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Europe PubMed Central

PubMed publication ID

3 August 2017

Christopher L Millington

2

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Europe PubMed Central

PubMed publication ID

3 August 2017

Oliver J Wilkinson

3

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Europe PubMed Central

PubMed publication ID

3 August 2017

Andrew S Marriott

4

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Europe PubMed Central

PubMed publication ID

3 August 2017

Amanda J Watson

5

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Europe PubMed Central

PubMed publication ID

3 August 2017

Onrapak Reamtong

6

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

David M Williams

8

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Geoffrey P Margison

9

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3 August 2017

Andrew C Povey

10

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3 August 2017

language of work or name

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publication date

17 January 2013

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Europe PubMed Central

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3 August 2017

Nucleic Acids Research

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Europe PubMed Central

PubMed publication ID

3 August 2017

41

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Europe PubMed Central

PubMed publication ID

3 August 2017

5

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

3047-3055

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

copyright license

Creative Commons Attribution-NonCommercial 3.0 Unported

7 November 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

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Atl1 Regulates Choice between Global Genome and Transcription-Coupled Repair of O6-Alkylguanines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597670

7 July 2018

A large prospective study of meat consumption and colorectal cancer risk: an investigation of potential mechanisms underlying this association

1 reference

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7 July 2018

Diet, fecal water, and colon cancer--development of a biomarker

1 reference

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7 July 2018

Flipping of alkylated DNA damage bridges base and nucleotide excision repair

1 reference

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7 July 2018

Effect of processed and red meat on endogenous nitrosation and DNA damage

1 reference

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7 July 2018

QCAL--a novel standard for assessing instrument conditions for proteome analysis

1 reference

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7 July 2018

Processed meat and colorectal cancer: a review of epidemiologic and experimental evidence

1 reference

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7 July 2018

Pathophysiology, clinical presentation, and management of colon cancer.

1 reference

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7 July 2018

Methylation pattern of the O6-methylguanine-DNA methyltransferase gene in colon during progressive colorectal tumorigenesis.

1 reference

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7 July 2018

Molecular classification and correlates in colorectal cancer

1 reference

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7 July 2018

MGMT: key node in the battle against genotoxicity, carcinogenicity and apoptosis induced by alkylating agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597670

7 July 2018

Novel synthesis of O6-alkylguanine containing oligodeoxyribonucleotides as substrates for the human DNA repair protein, O6-methylguanine DNA methyltransferase (MGMT).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597670

7 July 2018

Inhibition of O6-methylguanine-DNA methyltransferase by an alkyltransferase-like protein from Escherichia coli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597670

7 July 2018

Alkylation damage in DNA and RNA--repair mechanisms and medical significance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597670

7 July 2018

Variability and regulation of O6-alkylguanine-DNA alkyltransferase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597670

7 July 2018

Mechanisms of carcinogenicity/chemotherapy by O6-methylguanine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597670

7 July 2018

Elevated levels of the pro-carcinogenic adduct, O(6)-methylguanine, in normal DNA from the cancer prone regions of the large bowel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597670

7 July 2018

Repair of O(6)-alkylguanine by alkyltransferases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597670

7 July 2018

Transgenic systems in studies on genotoxicity of alkylating agents: critical lesions, thresholds and defense mechanisms.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597670

7 July 2018

Low O6-alkylguanine DNA-alkyltransferase activity in normal colorectal tissue is associated with colorectal tumours containing a GC-->AT transition in the K-ras oncogene.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597670

7 July 2018

Presence of N2-(deoxyguanosin-8-yl)-2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (dG-C8-MeIQx) in human tissues.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597670

7 July 2018

High levels of DNA adducts in human colon are associated with colorectal cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597670

7 July 2018

On the quantitative relationship between O6-methylguanine residues in genomic DNA and production of sister-chromatid exchanges, mutations and lethal events in a Mer- human tumor cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597670

7 July 2018

Relevance of nitrosamines to human cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597670

7 July 2018

Studies of the repair of O6-alkylguanine and O4-alkylthymine in DNA by alkyltransferases from mammalian cells and bacteria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597670

7 July 2018

Mechanisms and experimental and epidemiological evidence relating dietary fibre (non-starch polysaccharides) and starch to protection against large bowel cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597670

7 July 2018

Laboratory and epidemiologic studies of fecapentaenes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597670

7 July 2018

The detection of alkylation damage in the DNA of human gastrointestinal tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597670

7 July 2018

Repair of DNA containing O6-alkylguanine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597670

7 July 2018

Dietary fiber and colorectal cancer risk: a nested case-control study using food diaries

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKS1476

21 January 2018

Evidence of anti-benzo[a]pyrene diolepoxide-DNA adduct formation in human colon mucosa.

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKS1476

21 January 2018

Red meat enhances the colonic formation of the DNA adduct O6-carboxymethyl guanine: implications for colorectal cancer risk

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKS1476

21 January 2018

MGMT Ile143Val polymorphism, dietary factors and the risk of breast, colorectal and prostate cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC)-Norfolk study

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKS1476

21 January 2018

O6-methylguanine-DNA methyltransferase Leu84Phe and Ile143Val polymorphisms and risk of colorectal cancer in the Nurses' Health Study and Physicians' Health Study (United States).

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKS1476

21 January 2018

Reduced MGMT activity in human colorectal adenomas is associated with K-ras GC->AT transition mutations in a population exposed to methylating agents

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKS1476

21 January 2018

Convenient and efficient syntheses of oligodeoxyribonucleotides containing O(6)-(carboxymethyl)guanine and O(6)-(4-oxo-4-(3-pyridyl)butyl)guanine

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKS1476

21 January 2018

An approach based on ultra-high pressure liquid chromatography-tandem mass spectrometry to quantify O6-methyl and O6-carboxymethylguanine DNA adducts in intestinal cell lines

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKS1476

21 January 2018

Promoter hypermethylation of the DNA repair gene O(6)-methylguanine-DNA methyltransferase is associated with the presence of G:C to A:T transition mutations in p53 in human colorectal tumorigenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597670

27 October 2018

Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is associated with G to A mutations in K-ras in colorectal tumorigenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597670

27 October 2018

Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597670

27 October 2018

The cytotoxicity of DNA carboxymethylation and methylation by the model carboxymethylating agent azaserine in human cells

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKS1476

21 January 2018

Nitrosated glycine derivatives as a potential source of O6-methylguanine in DNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/23335782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Repair of O6-benzylguanine by the Escherichia coli Ada and Ogt and the human O6-alkylguanine-DNA alkyltransferases

1 reference

https://pubmed.ncbi.nlm.nih.gov/23335782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1093/NAR/GKS1476

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

ResearchGate publication ID

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