Biology and genetics of colorectal cancer (Q34558159)

3 August 2017

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title

Biology and genetics of colorectal cancer (English)

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3 August 2017

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Walker J

1

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PubMed ID

11887987

3 August 2017

Quirke P

series ordinal

2

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PubMed ID

11887987

3 August 2017

language of work or name

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1 October 2001

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European Journal of Cancer

3 August 2017

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3 August 2017

37 Suppl 7

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3 August 2017

S163-72

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Tissue microarray (TMA) technology: miniaturized pathology archives for high-throughput in situ studies

3 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

Carcinogenesis and natural selection: a new perspective to the genetics and epigenetics of colorectal cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

Aberrant crypt foci in the human colon: frequency and histologic patterns in patients with colorectal cancer or diverticular disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

Familial adenomatous polyposis: more evidence for disease diversity and genetic heterogeneity

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

Biology of the adenomatous polyposis coli tumor suppressor

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

Complex formation of adenomatous polyposis coli gene product and axin facilitates glycogen synthase kinase-3 beta-dependent phosphorylation of beta-catenin and down-regulates beta-catenin.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

Incidence of Hereditary Nonpolyposis Colorectal Cancer and the Feasibility of Molecular Screening for the Disease

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

Familial endometrial cancer in female carriers of MSH6 germline mutations

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

Germline mutation of MSH6 as the cause of hereditary nonpolyposis colorectal cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

Mutations of two PMS homologues in hereditary nonpolyposis colon cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

Mismatch repair defects in cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

Alternative genetic pathways in colorectal carcinogenesis.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

Microsatellite instability in the insulin–like growth factor II receptor gene in gastrointestinal tumours

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

The DNA repair gene MBD4 (MED1) is mutated in human carcinomas with microsatellite instability

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

Prognostic significance of extensive microsatellite instability in sporadic clinicopathological stage C colorectal cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

Tumour infiltrating lymphocytes and apoptosis are independent features in colorectal cancer stratified according to microsatellite instability status

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

Choice of management strategy for colorectal cancer based on a diagnostic immunohistochemical test for defective mismatch repair

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

Immunohistochemistry for hMLH1 and hMSH2: a practical test for DNA mismatch repair-deficient tumors

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

Efficient detection of hereditary nonpolyposis colorectal cancer gene carriers by screening for tumor microsatellite instability before germline genetic testing.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

Generalized Intestinal Polyposis and Melanin Spots of the Oral Mucosa, Lips and Digits

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

Increased risk of cancer in the Peutz-Jeghers syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

Localization of a susceptibility locus for Peutz-Jeghers syndrome to 19p using comparative genomic hybridization and targeted linkage analysis

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

A serine/threonine kinase gene defective in Peutz-Jeghers syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

Growth suppression by Lkb1 is mediated by a G(1) cell cycle arrest

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

Peutz-Jeghers syndrome: confirmation of linkage to chromosome 19p13.3 and identification of a potential second locus, on 19q13.4.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

Molecular genetic alterations in hamartomatous polyps and carcinomas of patients with Peutz-Jeghers syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

The risk of gastrointestinal carcinoma in familial juvenile polyposis

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

A gene for familial juvenile polyposis maps to chromosome 18q21.1.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

Down-regulation of TGF-beta receptors in human colorectal cancer: implications for cancer development

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https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

Familial colorectal cancer in Ashkenazim due to a hypermutable tract in APC.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

APC I1307K increases risk of transition from polyp to colorectal carcinoma in Ashkenazi Jews

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

The prevalence of polyps of the large intestine in Oslo: an autopsy study

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

The type of somatic mutation at APC in familial adenomatous polyposis is determined by the site of the germline mutation: a new facet to Knudson's 'two-hit' hypothesis

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

PPARdelta is an APC-regulated target of nonsteroidal anti-inflammatory drugs

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

Sulindac inhibits activation of the NF-kappaB pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

Cyclooxygenase regulates angiogenesis induced by colon cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

Low O6-alkylguanine DNA-alkyltransferase activity in normal colorectal tissue is associated with colorectal tumours containing a GC-->AT transition in the K-ras oncogene.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

Molecular interactions in the Vogelstein model of colorectal carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

1 reference

7 January 2021

Mad-related genes in the human

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

Progression from colorectal adenoma to carcinoma is associated with non-random chromosomal gains as detected by comparative genomic hybridisation

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

p53, the cellular gatekeeper for growth and division

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

Mutations in the APC tumour suppressor gene cause chromosomal instability

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

Prognostic significance of DNA aneuploidy and cell proliferation in rectal adenocarcinomas

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

DNA aneuploidy in colorectal adenomas

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

DNA content and the adenoma-carcinoma sequence in the colorectum

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

Mutations of mitotic checkpoint genes in human cancers

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

Splitting the chromosome: cutting the ties that bind sister chromatids

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

Securin is required for chromosomal stability in human cells

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

Cytogenetics of colorectal adenocarcinomas

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

beta-catenin regulates the expression of the matrix metalloproteinase-7 in human colorectal cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

Methylation of the oestrogen receptor CpG island links ageing and neoplasia in human colon

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

CpG-island methylation in aging and cancer.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

CpG island methylator phenotype in colorectal cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

Aberrant CpG-island methylation has non-random and tumour-type-specific patterns.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

Promoter hypermethylation--can this change alone ever designate true tumor suppressor gene function?

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

Methylation and colorectal cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

Alterations in DNA Methylation: A Fundamental Aspect of Neoplasia

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

The relationship between cyclooxygenase-2 expression and colorectal cancer.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

Different mechanisms in the tumorigenesis of proximal and distal colon cancers

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

Molecular staging of colorectal cancer: K-ras mutation analysis of lymph nodes upstages Dukes B patients

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

Somatic mutation screening: identification of individuals harboring K-ras mutations with the use of plasma DNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

Detection of tumour DNA in serum of colorectal cancer patients

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

Detection and monitoring of serum p53 antibodies in patients with colorectal cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

Mutations of the p53 gene in the stool of patients with resectable colorectal cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

Identification of subjects at risk for colorectal carcinoma through a test based on K-ras determination in the stool

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

Colorectal cancer screening by detection of altered human DNA in stool: feasibility of a multitarget assay panel

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

Tissue microarrays: what will they bring to molecular and anatomic pathology?

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

Clinical importance of DNA content in rectal cancer measured by flow cytometry

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

Kirsten ras mutations in patients with colorectal cancer: the multicenter "RASCAL" study.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

Association of p53 mutations with short survival in colorectal cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

p53 mutations in colorectal cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

Increased p53 protein content of colorectal tumours correlates with poor survival.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

Cytoplasmic accumulation of p53 protein: an independent prognostic indicator in colorectal adenocarcinomas.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

Allelic loss of chromosome 18q and prognosis in colorectal cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

Allelic loss on chromosome 18q as a prognostic marker in stage II colorectal cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

Association of tumour site and sex with survival benefit from adjuvant chemotherapy in colorectal cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

Chemotherapy for colorectal cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

Polymorphisms of the repeated sequences in the enhancer region of the thymidylate synthase gene promoter may predict downstaging after preoperative chemoradiation in rectal cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

Functional analysis and DNA polymorphism of the tandemly repeated sequences in the 5'-terminal regulatory region of the human gene for thymidylate synthase

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

Adjuvant active specific immunotherapy for human colorectal cancer: 6.5-year median follow-up of a phase III prospectively randomized trial

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

Ep-CAM: a human epithelial antigen is a homophilic cell-cell adhesion molecule

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

Randomised trial of monoclonal antibody for adjuvant therapy of resected Dukes' C colorectal carcinoma. German Cancer Aid 17-1A Study Group

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2980018-6

7 January 2021

10.1016/S0959-8049(01)80018-6

Identifiers

DOI

1 reference

3 August 2017

1 reference

PubMed ID

11887987