Common genetic variants highlight the role of insulin resistance and body fat distribution in type 2 diabetes, independent of obesity (Q34559688)

3 August 2017

title

Common genetic variants highlight the role of insulin resistance and body fat distribution in type 2 diabetes, independent of obesity (English)

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Françoise Clavel-Chapelon

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Françoise Clavel-Chapelon

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Inês Barroso

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Inês Barroso

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Claudia Langenberg

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Claudia Langenberg

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Vilmantas Giedraitis

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Vilmantas Giedraitis

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Heiner Boeing

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Heiner Boeing

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Aurelio Barricarte

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Luca A Lotta

Luca A Lotta

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Nita G. Forouhi

Nita G Forouhi

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Sara Grioni

Sara Grioni

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Matthias B Schulze

Matthias B Schulze

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Paul W. Franks

Paul W Franks

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Carlotta Sacerdote

Carlotta Sacerdote

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Domenico Palli

Domenico Palli

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Anne Tjønneland

Anne Tjonneland

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Rudolf Kaaks

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Rudolf Kaaks

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David B Savage

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Rosario Tumino

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Rosario Tumino

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Kim Overvad

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Afshan Siddiq

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Mark McCarthy

Mark I McCarthy

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Salvatore Panico

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Salvatore Panico

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Nicholas J Wareham

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Erik Ingelsson

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Guy Fagherazzi

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Tove Fall

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Hanieh Yaghootkar

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Jacqueline M Dekker

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Nadia Slimani

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Ele Ferrannini

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Tilman Kühn

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Stephen J Sharp

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Robert A Scott

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Leif C Groop

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Ivonne Sluijs

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Olov Rolandsson

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Annemieke M W Spijkerman

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Annemieke Mw Spijkerman

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Francesca L Crowe

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Dorota Pasko

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Larraitz Arriola

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Beverley Balkau

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Nina Roswall

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Diana Gavrila

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María José Sánchez Pérez

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María-José Sánchez

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Adam Barker

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Timothy J Key

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Peter M Nilsson

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J Ramón Quirós

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Núria Sala

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Daphne L van der A

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RISC study group

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EPIC-InterAct consortium

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Mark Walker

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Tim M Frayling

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3 August 2017

language of work or name

English

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publication date

19 June 2014

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3 August 2017

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volume

63

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issue

12

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3 August 2017

page(s)

4378-4387

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Impact of type 2 diabetes susceptibility variants on quantitative glycemic traits reveals mechanistic heterogeneity

3 August 2017

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Genetic predisposition to obesity leads to increased risk of type 2 diabetes

7 July 2018

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Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

7 July 2018

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7 July 2018

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Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

7 July 2018

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Detailed physiologic characterization reveals diverse mechanisms for novel genetic Loci regulating glucose and insulin metabolism in humans

7 July 2018

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New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

7 July 2018

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Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge

7 July 2018

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7 July 2018

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7 July 2018

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Postreceptor insulin resistance contributes to human dyslipidemia and hepatic steatosis

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Insulin Secretion in Response to Glycemic Stimulus: Relation of Delayed Initial Release to Carbohydrate intolerance in Mild Diabetes Mellitus*

7 July 2018

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Glucose clamp technique: a method for quantifying insulin secretion and resistance

7 July 2018

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Association between birth weight and visceral fat in adults

7 July 2018

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Proinsulin and acute insulin response independently predict Type 2 diabetes mellitus in men--report from 27 years of follow-up study

27 October 2018

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Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp.

27 October 2018

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27 October 2018

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27 October 2018

Identifiers

DOI

10.2337/DB14-0319

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3 August 2017

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3 August 2017

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