Heterozygosity and functional allelic variation in the Candida albicans efflux pump genes CDR1 and CDR2. (Q34561878)

3 August 2017

Heterozygosity and functional allelic variation in the Candida albicans efflux pump genes CDR1 and CDR2. (English)

1 reference

3 August 2017

1 reference

1 reference

Sarah Tsao

2

0 references

Erwin Lamping

Erwin Lamping

4

0 references

Ann R Holmes

Ann R Holmes

1

0 references

Jan Schmid

Jan Schmid

10

0 references

Barbara Holland

Barbara R Holland

9

0 references

Richard D. Cannon

Richard D Cannon

11

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author name string

Soo-Wee Ong

3

1 reference

3 August 2017

Kyoko Niimi

5

1 reference

3 August 2017

Brian C Monk

6

1 reference

3 August 2017

Masakazu Niimi

7

1 reference

3 August 2017

Aki Kaneko

8

1 reference

3 August 2017

language of work or name

English

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publication date

30 August 2006

1 reference

3 August 2017

Molecular Microbiology

1 reference

3 August 2017

62

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3 August 2017

1

1 reference

3 August 2017

170-186

1 reference

The Candida Genome Database (CGD), a community resource for Candida albicans gene and protein information

3 August 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05357.X

Application of real-time quantitative PCR to molecular analysis of Candida albicans strains exhibiting reduced susceptibility to azoles

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05357.X

Role of accurate mass measurement (+/- 10 ppm) in protein identification strategies employing MS or MS/MS and database searching.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05357.X

TAC1, transcriptional activator of CDR genes, is a new transcription factor involved in the regulation of Candida albicans ABC transporters CDR1 and CDR2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05357.X

A mutation in Tac1p, a transcription factor regulating CDR1 and CDR2, is coupled with loss of heterozygosity at chromosome 5 to mediate antifungal resistance in Candida albicans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05357.X

ATPase and multidrug transport activities of the overexpressed yeast ABC protein Yor1p

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05357.X

The transmembrane domain 10 of the yeast Pdr5p ABC antifungal efflux pump determines both substrate specificity and inhibitor susceptibility.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05357.X

Genome-wide single-nucleotide polymorphism map for Candida albicans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05357.X

Demonstration of loss of heterozygosity by single-nucleotide polymorphism microarray analysis and alterations in strain morphology in Candida albicans strains during infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05357.X

Population structure of Candida albicans, a member of the human flora, as determined by microsatellite loci.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05357.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05357.X

Molecular markers reveal that population structure of the human pathogen Candida albicans exhibits both clonality and recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05357.X

Delta plots: a tool for analyzing phylogenetic distance data

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05357.X

Identification of a mating type-like locus in the asexual pathogenic yeast Candida albicans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05357.X

Evidence for mating of the "asexual" yeast Candida albicans in a mammalian host

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05357.X

Pharmacogenomics of drug transporters: a new approach to functional analysis of the genetic polymorphisms of ABCB1 (P-glycoprotein/MDR1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05357.X

Purification and characterization of the N-terminal nucleotide binding domain of an ABC drug transporter of Candida albicans: uncommon cysteine 193 of Walker A is critical for ATP hydrolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05357.X

Covalent modification of cysteine 193 impairs ATPase function of nucleotide-binding domain of a Candida drug efflux pump

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05357.X

ABC multidrug transporter Cdr1p of Candida albicans has divergent nucleotide-binding domains which display functional asymmetry

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05357.X

Mechanism of ABC transporters: a molecular dynamics simulation of a well characterized nucleotide-binding subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05357.X

The diploid genome sequence of Candida albicans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05357.X

Comparison of gene expression profiles of Candida albicans azole-resistant clinical isolates and laboratory strains exposed to drugs inducing multidrug transporters

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05357.X

Homozygosity at the MTL locus in clinical strains of Candida albicans: karyotypic rearrangements and tetraploid formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05357.X

Genome-wide expression profiling of the response to azole, polyene, echinocandin, and pyrimidine antifungal agents in Candida albicans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05357.X

Location of the rhodamine-binding site in the human multidrug resistance P-glycoprotein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05357.X

Mechanisms of fluconazole resistance in Candida albicans isolates from Japanese AIDS patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05357.X

Induction of mating in Candida albicans by construction of MTLa and MTLalpha strains

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05357.X

Through a glass opaquely: the biological significance of mating in Candida albicans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05357.X

Expression regulation of the yeast PDR5 ATP-binding cassette (ABC) transporter suggests a role in cellular detoxification during the exponential growth phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05357.X

CDD: a Conserved Domain Database for protein classification

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05357.X

Inducible azole resistance associated with a heterogeneous phenotype in Candida albicans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05357.X

Cloning, sequencing, expression and allelic sequence diversity of ERG3 (C-5 sterol desaturase gene) in Candida albicans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05357.X

An SNP-based PCR assay to differentiate between Listeria monocytogenes lineages derived from phylogenetic analysis of the sigB gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05357.X

Functional expression of Candida albicans drug efflux pump Cdr1p in a Saccharomyces cerevisiae strain deficient in membrane transporters

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05357.X

Chemosensitization of fluconazole resistance in Saccharomyces cerevisiae and pathogenic fungi by a D-octapeptide derivative

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05357.X

Regulated overexpression of CDR1 in Candida albicans confers multidrug resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05357.X

Membrane raft lipid constituents affect drug susceptibilities of Candida albicans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05357.X

Prevalence of molecular mechanisms of resistance to azole antifungal agents in Candida albicans strains displaying high-level fluconazole resistance isolated from human immunodeficiency virus-infected patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05357.X

Genome-wide expression profile analysis reveals coordinately regulated genes associated with stepwise acquisition of azole resistance in Candida albicans clinical isolates

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05357.X

Alanine scanning of transmembrane helix 11 of Cdr1p ABC antifungal efflux pump of Candida albicans: identification of amino acid residues critical for drug efflux.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05357.X

Mechanisms of resistance to azole antifungal agents in Candida albicans isolates from AIDS patients involve specific multidrug transporters

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05357.X

Reversal of antifungal resistance mediated by ABC efflux pumps from Candida albicans functionally expressed in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05357.X

The Candida albicans Cdr2p ATP-binding cassette (ABC) transporter confers resistance to caspofungin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05357.X

Functional characterization of Candida albicans ABC transporter Cdr1p.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05357.X

Substitution of threonine-1351 in the multidrug transporter Cdr1p of Candida albicans results in hypersusceptibility to antifungal agents and threonine-1351 is essential for synergic effects of calcineurin inhibitor FK520.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05357.X

Host versus in vitro signals and intrastrain allelic differences in the expression of a Candida albicans virulence gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05357.X

Genetic evidence for recombination in Candida albicans based on haplotype analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05357.X

The yeast Pdr15p ATP-binding cassette (ABC) protein is a general stress response factor implicated in cellular detoxification.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05357.X

Chromosome loss followed by duplication is the major mechanism of spontaneous mating-type locus homozygosis in Candida albicans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05357.X

Allele-specific gene targeting in Candida albicans results from heterology between alleles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05357.X

Sixty alleles of the ALS7 open reading frame in Candida albicans: ALS7 is a hypermutable contingency locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05357.X

Allelic variation in the contiguous loci encoding Candida albicans ALS5, ALS1 and ALS9

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05357.X

10.1111/J.1365-2958.2006.05357.X

21 January 2018

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DOI

1 reference

3 August 2017

1 reference