TNF receptor subtype signalling: differences and cellular consequences (Q34565473)

3 August 2017

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title

TNF receptor subtype signalling: differences and cellular consequences (English)

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3 August 2017

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David J MacEwan

1

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publication date

1 June 2002

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3 August 2017

16

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inferred from page(s)

published in

Cellular Signalling

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3 August 2017

14

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3 August 2017

477-492

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3 August 2017

6

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Binding, gating, affinity and efficacy: the interpretation of structure-activity relationships for agonists and of the effects of mutating receptors

3 August 2017

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https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Inverse, protean, and ligand-selective agonism: matters of receptor conformation

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https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Characterization of receptors for human tumour necrosis factor and their regulation by gamma-interferon

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

High affinity binding of 125I-labeled human tumor necrosis factor (LuKII) to specific cell surface receptors

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https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

A high molecular weight component of the human tumor necrosis factor receptor is associated with cytotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Cellular receptor for 125I-labeled tumor necrosis factor: specific binding, affinity labeling, and relationship to sensitivity

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https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Receptor binding and activation of polymorphonuclear neutrophils by tumor necrosis factor-alpha.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Characterization of the tumour necrosis factor receptor in human placenta

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https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Reduction in tumor necrosis factor receptor affinity and cytotoxicity by glucocorticoids

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Complementary DNA cloning of a receptor for tumor necrosis factor and demonstration of a shed form of the receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Molecular Cloning and Expression of Human and Rat Tumor Necrosis Factor Receptor Chain (p60) and Its Soluble Derivative, Tumor Necrosis Factor-Binding Protein

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Cloning of human tumor necrosis factor (TNF) receptor cDNA and expression of recombinant soluble TNF-binding protein

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Molecular cloning and expression of the human 55 kd tumor necrosis factor receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Molecular cloning and expression of a receptor for human tumor necrosis factor

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https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Cloning, expression and cross-linking analysis of the murine p55 tumor necrosis factor receptor

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https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Molecular cloning and expression of the type 1 and type 2 murine receptors for tumor necrosis factor

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https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Cloning and expression of cDNAs for two distinct murine tumor necrosis factor receptors demonstrate one receptor is species specific

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https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Molecular cloning and expression of the mouse Tnf receptor type b

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https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Tumor necrosis factor (TNF).

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https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

TNF alpha and the TNF receptor superfamily: structure-function relationship(s).

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Tumour necrosis factors receptor associated signalling molecules and their role in activation of apoptosis, JNK and NF-kappaB.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Signal transduction by tumour necrosis factor and tumour necrosis factor related ligands and their receptors

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https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

The TNF and TNF receptor superfamilies: integrating mammalian biology

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https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Tumor necrosis factor receptor-associated factor (TRAF) family: adapter proteins that mediate cytokine signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

A domain in TNF receptors that mediates ligand-independent receptor assembly and signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

The tumour necrosis factor receptor family: life or death choices

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https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

A novel domain within the 55 kd TNF receptor signals cell death

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https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Prevention of constitutive TNF receptor 1 signaling by silencer of death domains

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Distinct adapter proteins mediate acid versus neutral sphingomyelinase activation through the p55 receptor for tumor necrosis factor.

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https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Regulation of ceramide production and apoptosis

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https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

BRE: a modulator of TNF-alpha action

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

The TNF-receptor-associated factor family: scaffold molecules for cytokine receptors, kinases and their regulators

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation

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https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

RIP: a novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death

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https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex

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https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex

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https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Regulated commitment of TNF receptor signaling: a molecular switch for death or activation.

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https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

NF-kappaB-inducing kinase activates IKK-alpha by phosphorylation of Ser-176

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https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

The tumor necrosis factor-inducible zinc finger protein A20 interacts with TRAF1/TRAF2 and inhibits NF-kappaB activation

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https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

ASK1 is essential for JNK/SAPK activation by TRAF2

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https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Tumor necrosis factor signaling to stress-activated protein kinase (SAPK)/Jun NH2-terminal kinase (JNK) and p38. Germinal center kinase couples TRAF2 to mitogen-activated protein kinase/ERK kinase kinase 1 and SAPK while receptor interacting [...]

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

TNF-mediated activation of the stress-activated protein kinase pathway: TNF receptor-associated factor 2 recruits and activates germinal center kinase related

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Signaling by proinflammatory cytokines: oligomerization of TRAF2 and TRAF6 is sufficient for JNK and IKK activation and target gene induction via an amino-terminal effector domain

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Tumor Necrosis Factor-α Activates the Sphingomyelin Signal Transduction Pathway in a Cell-Free System

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Characterization of a ceramide-activated protein kinase: stimulation by tumor necrosis factor alpha

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Kinase suppressor of Ras is ceramide-activated protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Phosphorylation of Raf by ceramide-activated protein kinase

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https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Signal transduction of stress via ceramide

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https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Identification of Grb2 as a novel binding partner of tumor necrosis factor (TNF) receptor I.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Inhibition of death receptor signals by cellular FLIP

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https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors

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https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

The caspase-8 inhibitor FLIP promotes activation of NF-kappaB and Erk signaling pathways

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https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

MADD, a novel death domain protein that interacts with the type 1 tumor necrosis factor receptor and activates mitogen-activated protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Engagement of tumor necrosis factor (TNF) receptor 1 leads to ATF-2- and p38 mitogen-activated protein kinase-dependent TNF-alpha gene expression

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https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Apoptotic and necrotic cell death induced by death domain receptors.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Dual signaling of the Fas receptor: initiation of both apoptotic and necrotic cell death pathways

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https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Inhibition of caspases increases the sensitivity of L929 cells to necrosis mediated by tumor necrosis factor.

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https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Non-specific effects of methyl ketone peptide inhibitors of caspases

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https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice

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https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme

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https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Caspase knockouts: matters of life and death.

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https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Two tumour necrosis factor receptors: structure and function.

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https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

The death domain kinase RIP mediates the TNF-induced NF-kappaB signal

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https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Caspases: the executioners of apoptosis

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https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

BCL-2 family: regulators of cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

T cell life and death signalling via TNF-receptor family members

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https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Proteolytic activation of protein kinase C delta by an ICE-like protease in apoptotic cells.

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https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Defying death after DNA damage.

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https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

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https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Noncaspase proteases in apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Life and death decisions: regulation of apoptosis by proteolysis of signaling molecules

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Calcium signalling and the regulation of apoptosis.

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https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Cleavage of the calpain inhibitor, calpastatin, during apoptosis

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https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Control of apoptosis by IP(3) and ryanodine receptor driven calcium signals

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https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Selective down-regulation of IP(3)receptor subtypes by caspases and calpain during TNF alpha -induced apoptosis of human T-lymphoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Tumor necrosis factor-alpha-inducible IkappaBalpha proteolysis mediated by cytosolic m-calpain. A mechanism parallel to the ubiquitin-proteasome pathway for nuclear factor-kappab activation

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Cachectin/tumor necrosis factor stimulates collagenase and prostaglandin E2 production by human synovial cells and dermal fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Reduced tumour necrosis factor-induced cytotoxicity by inhibitors of the arachidonic acid metabolism

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Tumour necrosis factor (cachectin) induces phospholipase A2 activity and synthesis of a phospholipase A2-activating protein in endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Recombinant tumor necrosis factor and interleukin-1 both stimulate human synovial cell arachidonic acid release and phospholipid metabolism

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https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Tumor necrosis factor receptor-mediated signaling pathways

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https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

TNF activates NF-kappa B by phosphatidylcholine-specific phospholipase C-induced "acidic" sphingomyelin breakdown

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Tumor necrosis factor induces rapid production of 1'2'diacylglycerol by a phosphatidylcholine-specific phospholipase C.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Function of the p55 tumor necrosis factor receptor "death domain" mediated by phosphatidylcholine-specific phospholipase C.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C

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https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Differential activation of phospholipases during necrosis or apoptosis: A comparative study using tumor necrosis factor and anti-Fas antibodies

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Changes of phospholipase D activity in TNF-alpha and anti-Fas/Apo1 monoclonal antibody induced apoptosis in HL-60 and A20 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Priming of human neutrophil superoxide generation by tumour necrosis factor-alpha is signalled by enhanced phosphatidylinositol 3,4,5-trisphosphate but not inositol 1,4,5-trisphosphate accumulation.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Effect of TNF-alpha on SMIT mRNA levels and myo-inositol accumulation in cultured endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Tumor necrosis factor-alpha autoregulates interleukin-6 synthesis via activation of protein kinase C. Function of sphingosine 1-phosphate and phosphatidylcholine-specific phospholipase C.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Tumor necrosis factor alpha decreases inositol phosphate formation and phosphatidylinositol-bisphosphate (PIP2) synthesis in rat cardiomyocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Functional dichotomy of neutral and acidic sphingomyelinases in tumor necrosis factor signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Functions of sphingolipids and sphingolipid breakdown products in cellular regulation

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Diversity and complexity of ceramide signalling in apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Enzymes of sphingolipid metabolism: from modular to integrative signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

BAD Enables Ceramide to Signal Apoptosis via Ras and Raf-1

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Sphingolipid metabolites differentially regulate extracellular signal-regulated kinase and stress-activated protein kinase cascades

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Ceramide-induced translocation of protein kinase C-delta and -epsilon to the cytosol. Implications in apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Ceramide inactivates cellular protein kinase Calpha

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Functional dichotomy of protein kinase C (PKC) in tumor necrosis factor-alpha (TNF-alpha ) signal transduction in L929 cells. Translocation and inactivation of PKC by TNF-alpha.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Involvement of protein kinase C-beta and ceramide in tumor necrosis factor-alpha-induced but not Fas-induced apoptosis of human myeloid leukemia cells

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

PKC zeta is a molecular switch in signal transduction of TNF-alpha, bifunctionally regulated by ceramide and arachidonic acid

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Evidence for a role of MEK and MAPK during signal transduction by protein kinase C zeta

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Ceramide-dependent regulation of p42/p44 mitogen-activated protein kinase and c-Jun N-terminal-directed protein kinase in cultured airway smooth muscle cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

A novel arachidonic acid-selective cytosolic PLA2 contains a Ca(2+)-dependent translocation domain with homology to PKC and GAP

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Cell killing and induction of manganous superoxide dismutase by tumor necrosis factor-alpha is mediated by lipoxygenase metabolites of arachidonic acid

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Manganous superoxide dismutase is essential for cellular resistance to cytotoxicity of tumor necrosis factor

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Induction of manganous superoxide dismutase by tumor necrosis factor: possible protective mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Distinct PKC isoforms mediate the activation of cPLA2 and adenylyl cyclase by phorbol ester in RAW264.7 macrophages

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

cPLA2 is phosphorylated and activated by MAP kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

p38 mitogen-activated protein kinase phosphorylates cytosolic phospholipase A2 (cPLA2) in thrombin-stimulated platelets. Evidence that proline-directed phosphorylation is not required for mobilization of arachidonic acid by cPLA2

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Identification of the phosphorylation sites of cytosolic phospholipase A2 in agonist-stimulated human platelets and HeLa cells

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Phosphorylation and activation of cytosolic phospholipase A2 by 38-kDa mitogen-activated protein kinase in collagen-stimulated human platelets

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Cytoplasmic phospholipase A2 activity and gene expression are stimulated by tumor necrosis factor: dexamethasone blocks the induced synthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Tumour-necrosis-factor-mediated cytotoxicity is correlated with phospholipase-A2 activity, but not with arachidonic acid release per se.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Phospholipase A2 is necessary for tumor necrosis factor alpha-induced ceramide generation in L929 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Activation of p42/p44 mitogen-activated protein kinases (MAPK) and p38 MAPK by tumor necrosis factor (TNF) is mediated through the death domain of the 55-kDa TNF receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Stimulation of stress-activated but not mitogen-activated protein kinases by tumour necrosis factor receptor subtypes in airway smooth muscle

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Elevated cPLA2 levels as a mechanism by which the p70 TNF and p75 NGF receptors enhance apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Cleavage of human cytosolic phospholipase A2 by caspase-1 (ICE) and caspase-8 (FLICE).

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Fas-induced arachidonic acid release is mediated by Ca2+-independent phospholipase A2 but not cytosolic phospholipase A2, which undergoes proteolytic inactivation

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Involvement of caspase-dependent activation of cytosolic phospholipase A2 in tumor necrosis factor-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Studies on the role of protein kinases in the TNF-mediated enhancement of murine tumor cell-endothelial cell interactions

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Involvement of Protein Kinase C in Regulating Tumor Necrosis Factor α-Stimulated Progesterone Production in Rat Preovulatory Folliclesin Vitro*

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Serine phosphorylation of p60 tumor necrosis factor receptor by PKC-delta in TNF-alpha-activated neutrophils

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

The interaction of p62 with RIP links the atypical PKCs to NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Role of the protein kinase C lambda/iota isoform in nuclear factor-kappaB activation by interleukin-1beta or tumor necrosis factor-alpha: cell type specificities

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Stress-activated protein kinases: activation, regulation and function.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Differential activation of ERK and JNK mitogen-activated protein kinases by Raf-1 and MEKK

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Tumor necrosis factor receptors (Tnfr) in mouse fibroblasts deficient in Tnfr1 or Tnfr2 are signaling competent and activate the mitogen-activated protein kinase pathway with differential kinetics

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

TGF-beta-induced matrix proteins inhibit p42/44 MAPK and JNK activation and suppress TNF-mediated IkappaBalpha degradation and NF-kappaB nuclear translocation in L929 fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Selective activation of p38 mitogen-activated protein (MAP) kinase isoforms by the MAP kinase kinases MKK3 and MKK6

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Inhibition of p38 mitogen-activated protein kinase provides neuroprotection in cerebral focal ischemia

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Tumor necrosis factor-alpha mediates antiapoptotic signals partially via p38 MAP kinase activation in human eosinophils

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Activation of p38 mitogen-activated protein kinase in vivo selectively induces apoptosis of CD8(+) but not CD4(+) T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Activation of the p38 mitogen-activated protein kinase pathway by Epstein-Barr virus-encoded latent membrane protein 1 coregulates interleukin-6 and interleukin-8 production

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Activation of p38 mitogen-activated protein kinase by sodium salicylate leads to inhibition of tumor necrosis factor-induced IkappaB alpha phosphorylation and degradation

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Serine/threonine protein kinases and apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Tumor necrosis factor (TNF)-mediated kinase cascades: bifurcation of nuclear factor-kappaB and c-jun N-terminal kinase (JNK/SAPK) pathways at TNF receptor-associated factor 2

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

TRAIL/Apo2L activates c-Jun NH2-terminal kinase (JNK) via caspase-dependent and caspase-independent pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

MEK kinase 1, a substrate for DEVD-directed caspases, is involved in genotoxin-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

The regulation of anoikis: MEKK-1 activation requires cleavage by caspases

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Tumor necrosis factor-alpha activation of the c-Jun N-terminal kinase pathway in human neutrophils. Integrin involvement in a pathway leading from cytoplasmic tyrosine kinases apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

JNK and p53 stress signaling cascades are altered in MCF-7 cells resistant to tumor necrosis factor-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Modulated kinase activities in cells undergoing tumour necrosis factor-induced apoptotic cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Anti-TNF alpha therapy of rheumatoid arthritis: what have we learned?

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

The beginning of the end: IkappaB kinase (IKK) and NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

TRAF2-mediated activation of NF-kappa B by TNF receptor 2 and CD40

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

TRAF2 is essential for JNK but not NF-kappaB activation and regulates lymphocyte proliferation and survival

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Early lethality, functional NF-kappaB activation, and increased sensitivity to TNF-induced cell death in TRAF2-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

The distinct roles of TRAF2 and RIP in IKK activation by TNF-R1: TRAF2 recruits IKK to TNF-R1 while RIP mediates IKK activation

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

RIP2 is a novel NF-kappaB-activating and cell death-inducing kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Identification of CARDIAK, a RIP-like kinase that associates with caspase-1

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

RIP3, a novel apoptosis-inducing kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Tumor necrosis factor receptor (TNFR)-associated factor 2A (TRAF2A), a TRAF2 splice variant with an extended RING finger domain that inhibits TNFR2-mediated NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Anatomy of TRAF2. Distinct domains for nuclear factor-kappaB activation and association with tumor necrosis factor signaling proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Alymphoplasia is caused by a point mutation in the mouse gene encoding Nf-kappa b-inducing kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Essential role of nuclear factor (NF)-kappaB-inducing kinase and inhibitor of kappaB (IkappaB) kinase alpha in NF-kappaB activation through lymphotoxin beta receptor, but not through tumor necrosis factor receptor I

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Defective lymphotoxin-beta receptor-induced NF-kappaB transcriptional activity in NIK-deficient mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Differential IκB Kinase Activation and IκBα Degradation by Interleukin-1β and Tumor Necrosis Factor-α in Human U937 Monocytic Cells

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways are required for nuclear factor-kappaB p65 transactivation mediated by tumor necrosis factor.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Differential effects of lipopolysaccharide and tumor necrosis factor on monocytic IkappaB kinase signalsome activation and IkappaB proteolysis

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

The zinc finger protein A20 inhibits TNF-induced NF-kappaB-dependent gene expression by interfering with an RIP- or TRAF2-mediated transactivation signal and directly binds to a novel NF-kappaB-inhibiting protein ABIN

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Protein kinase Cmu downregulation of tumor-necrosis-factor-induced apoptosis correlates with enhanced expression of nuclear-factor-kappaB-dependent protective genes

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Dissociation of cytokine-induced phosphorylation of Bad and activation of PKB/akt: involvement of MEK upstream of Bad phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Caspase-dependent cleavage of signaling proteins during apoptosis. A turn-off mechanism for anti-apoptotic signals

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Ceramide induces the dephosphorylation and inhibition of constitutively activated Akt in PTEN negative U87mg cells

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Ceramide inhibits protein kinase B/Akt by promoting dephosphorylation of serine 473.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Inhibition of PKB/Akt1 by C2-ceramide involves activation of ceramide-activated protein phosphatase in PC12 cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Inhibition of Akt kinase by cell-permeable ceramide and its implications for ceramide-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

PI3-K/AKT regulation of NF-kappaB signaling events in suppression of TNF-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Tumor necrosis factor induces phosphorylation and translocation of BAD through a phosphatidylinositide-3-OH kinase-dependent pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Cyclic nucleotides suppress tumor necrosis factor alpha-mediated apoptosis by inhibiting caspase activation and cytochrome c release in primary hepatocytes via a mechanism independent of Akt activation

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Cytokine-induced apoptosis in epithelial HT-29 cells is independent of nitric oxide formation. Evidence for an interleukin-13-driven phosphatidylinositol 3-kinase-dependent survival mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

A phosphatidylinositol 3-kinase/Akt pathway, activated by tumor necrosis factor or interleukin-1, inhibits apoptosis but does not activate NFkappaB in human endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

TNF-alpha stimulation of MCP-1 expression is mediated by the Akt/PKB signal transduction pathway in vascular endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

A novel interaction between the juxtamembrane region of the p55 tumor necrosis factor receptor and phosphatidylinositol-4-phosphate 5-kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

c-Jun is a downstream target for ceramide-activated protein phosphatase in A431 cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Tumor necrosis factor employs a protein-tyrosine phosphatase to inhibit activation of KDR and vascular endothelial cell growth factor-induced endothelial cell proliferation

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Protein tyrosine kinase inhibitors block tumor necrosis factor-induced activation of nuclear factor-kappaB, degradation of IkappaBalpha, nuclear translocation of p65, and subsequent gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Induction of endothelial cell surface adhesion molecules by tumor necrosis factor is blocked by protein tyrosine phosphatase inhibitors: role of the nuclear transcription factor NF-kappa B.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Protein-tyrosine phosphatase inhibitors block tumor necrosis factor-dependent activation of the nuclear transcription factor NF-kappa B.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Pervanadate-induced nuclear factor-kappaB activation requires tyrosine phosphorylation and degradation of IkappaBalpha. Comparison with tumor necrosis factor-alpha

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Modulation of the nuclear factor kappa B pathway by Shp-2 tyrosine phosphatase in mediating the induction of interleukin (IL)-6 by IL-1 or tumor necrosis factor

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Specific macrophage receptor activity for advanced glycosylation end products inversely correlates with insulin levels in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Identity of tumour necrosis factor and the macrophage-secreted factor cachectin

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Soluble tumor necrosis factor receptors in sera from patients with insulin-dependent diabetes mellitus: relations to duration and complications of disease

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

New perspectives into the molecular pathogenesis and treatment of type 2 diabetes

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Potential role of TNF-alpha in the pathogenesis of insulin resistance and type 2 diabetes

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Through thick and thin: wasting, obesity, and TNF alpha

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Reduced tyrosine kinase activity of the insulin receptor in obesity-diabetes. Central role of tumor necrosis factor-alpha

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Tumor necrosis factor alpha inhibits signaling from the insulin receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Transmembrane tumor necrosis factor (TNF)-alpha inhibits adipocyte differentiation by selectively activating TNF receptor 1

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Characterisation of receptor-specific TNFalpha functions in adipocyte cell lines lacking type 1 and 2 TNF receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Protection from obesity-induced insulin resistance in mice lacking TNF-alpha function

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

TNF inhibits insulin induced STAT5 activation in differentiated mouse muscle cells pmi28.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Protein kinase C-zeta phosphorylates insulin receptor substrate-1 and impairs its ability to activate phosphatidylinositol 3-kinase in response to insulin.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Tumor necrosis factor‐mediated cell lysis in vitro: relationship to cAMP accumulation and guanine nucleotide‐binding proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Tumor necrosis factor alpha inhibits collagen alpha 1(I) gene expression in rat hepatic stellate cells through a G protein

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Azotemia, TNF alpha, and LPS prime the human neutrophil oxidative burst by distinct mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Modulation of transmembrane signalling in HL-60 granulocytes by tumour necrosis factor-alpha

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

TNF-alpha stimulates increased plasma membrane guanine nucleotide binding protein activity in polymorphonuclear leukocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Selective down-regulation of the G(q)alpha/G11alpha G-protein family in tumour necrosis factor-alpha induced cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

A human suppressor of c-Jun N-terminal kinase 1 activation by tumor necrosis factor alpha

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Ras signaling in tumor necrosis factor-induced apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

RIP2 is a Raf1-activated mitogen-activated protein kinase kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Regulation of Raf-1 kinase by TNF via its second messenger ceramide and cross-talk with mitogenic signalling

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Transcriptional regulation of rat Na(+)/H(+) exchanger isoform-2 (NHE-2) gene by Sp1 transcription factor

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Regulation of TNF-alpha-induced reorganization of the actin cytoskeleton and cell-cell junctions by Rho, Rac, and Cdc42 in human endothelial cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

LMP1 signal transduction differs substantially from TNF receptor 1 signaling in the molecular functions of TRADD and TRAF2

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Activation of the nuclear factor-kappaB by Rho, CDC42, and Rac-1 proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Roles of phosphatidylinositol 3-kinase and Rac in the nuclear signaling by tumor necrosis factor-alpha in rat-2 fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Differential role of calcium in tumour necrosis factor-mediated apoptosis and secretion of granulocyte-macrophage colony-stimulating factor in a T cell hybridoma.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Endothelin-stimulated Ca2+ mobilization by 3T3-L1 adipocytes is suppressed by tumor necrosis factor-alpha

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Tumor necrosis factor-alpha inhibits store-mediated Ca2+ entry in the human hepatocellular carcinoma cell line HepG2.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Interleukin-1β (IL-1β) and tumour necrosis factor (TNF) inhibit long-term potentiation in the rat dentate gyrus in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Tumor necrosis factor-alpha increases airway responsiveness and sputum neutrophilia in normal human subjects

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Tumour necrosis factor-alpha: the role of this multifunctional cytokine in asthma

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Potentiation by tumour necrosis factor-alpha of calcium signals induced by bradykinin and carbachol in human tracheal smooth muscle cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Activation of the TNF alpha-p55 receptor induces myocyte proliferation and modulates agonist-evoked calcium transients in cultured human tracheal smooth muscle cells

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Activation of p55 tumor necrosis factor-alpha receptor-1 coupled to tumor necrosis factor receptor-associated factor 2 stimulates intercellular adhesion molecule-1 expression by modulating a thapsigargin-sensitive pathway in human tracheal smooth mu

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Tumour necrosis factor-alpha activates a calcium sensitization pathway in guinea-pig bronchial smooth muscle

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Tumor necrosis factor-alpha augments contraction and cytosolic Ca(2+) sensitivity through phospholipase A(2) in bovine tracheal smooth muscle

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Slow increase in intranuclear and cytosolic free calcium concentrations in L929 cells is important in tumour necrosis factor-alpha-mediated cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Unmodified calcium concentrations in tumour necrosis factor receptor subtype-mediated apoptotic cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

TNF-alpha receptors simultaneously activate Ca2+ mobilisation and stress kinases in cultured sensory neurones.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Tumor necrosis factor: specific binding and internalization in sensitive and resistant cells

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Human TNF mutants with selective activity on the p55 receptor.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Characterization of a recombinant extracellular domain of the type 1 tumor necrosis factor receptor: evidence for tumor necrosis factor .alpha. induced receptor aggregation

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

The type 1 receptor (CD120a) is the high-affinity receptor for soluble tumor necrosis factor

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Phosphorylation of the tumor necrosis factor receptor CD120a (p55) recruits Bcl-2 and protects against apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Phosphorylation of tumor necrosis factor receptor CD120a (p55) by p42(mapk/erk2) induces changes in its subcellular localization

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Phosphorylation of the membrane proximal region of tumor necrosis factor receptor CD120a (p55) at ERK consensus sites

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Inhibition of protein tyrosine phosphatases causes phosphorylation of tyrosine-331 in the p60 TNF receptor and inactivates the receptor-associated kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

High levels of circulating soluble receptors for tumor necrosis factor in hairy cell leukemia and type B chronic lymphocytic leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Mice lacking the tumour necrosis factor receptor 1 are resistant to TNF-mediated toxicity but highly susceptible to infection by Listeria monocytogenes

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Differential requirement for caspase 9 in apoptotic pathways in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Essential contribution of caspase 3/CPP32 to apoptosis and its associated nuclear changes

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Deficiency in caspase-9 or caspase-3 induces compensatory caspase activation

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

The transmembrane form of tumor necrosis factor is the prime activating ligand of the 80 kDa tumor necrosis factor receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Generation and biological characterization of membrane-bound, uncleavable murine tumor necrosis factor.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Membrane tumor necrosis factor (TNF) induced cooperative signaling of TNFR60 and TNFR80 favors induction of cell death rather than virus production in HIV-infected T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

The two different receptors for tumor necrosis factor mediate distinct cellular responses

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Evidence for exclusive role in signalling of tumour necrosis factor p55 receptor and a potentiating function of p75 receptor on human endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Tumor necrosis factor (TNF)-alpha activates c-raf-1 kinase via the p55 TNF receptor engaging neutral sphingomyelinase.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Inhibition of death receptor-mediated gene induction by a cycloheximide-sensitive factor occurs at the level of or upstream of Fas-associated death domain protein (FADD)

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

The role of the two TNF receptors in proliferation, NF-kappa B activation and discrimination between TNF and LT alpha signalling in the human myeloma cell line OH-2.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Involvement of the tumor necrosis factor receptor p75 in mediating cytotoxicity and gene regulating activities

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Structure-activity studies of human tumour necrosis factors

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Human tumor necrosis factor mutants with preferential binding to and activity on either the R55 or R75 receptor.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Dissociation of TNF-alpha cytotoxic and proinflammatory activities by p55 receptor- and p75 receptor-selective TNF-alpha mutants.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

A human tumor necrosis factor p75 receptor agonist stimulates in vitro T cell proliferation but does not produce inflammation or shock in the baboon

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

A human tumor necrosis factor (TNF) alpha mutant that binds exclusively to the p55 TNF receptor produces toxicity in the baboon

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

A metalloprotease inhibitor blocks shedding of the 80-kD TNF receptor and TNF processing in T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Functional characterization of the human tumor necrosis factor receptor p75 in a transfected rat/mouse T cell hybridoma

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Tumor necrosis factor (TNF) receptor type 2 mediates thymocyte proliferation independently of TNF receptor type 1

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Tumor necrosis factor-alpha mediates both apoptotic cell death and cell proliferation in a human hematopoietic cell line dependent on mitotic activity and receptor subtype expression

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Both TNF receptors are required for direct TNF-mediated cytotoxicity in microvascular endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

The p70 tumor necrosis factor receptor mediates cytotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Dimerization of chimeric erythropoietin/75 kDa tumour necrosis factor (TNF) receptors transduces TNF signals: necessity for the 75 kDa-TNF receptor transmembrane domain.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Tumor necrosis factor's cytotoxic activity is signaled by the p55 TNF receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Cytotoxicity in L929 murine fibrosarcoma cells after triggering of transfected human p75 tumour necrosis factor (TNF) receptor is mediated by endogenous murine TNF.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Continuous autotropic signaling by membrane-expressed tumor necrosis factor

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Induction of cell death by tumour necrosis factor (TNF) receptor 2, CD40 and CD30: a role for TNF-R1 activation by endogenous membrane-anchored TNF.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Interleukin-4 down-regulates both forms of tumor necrosis factor receptor and receptor-mediated apoptosis, NF-kappaB, AP-1, and c-Jun N-terminal kinase. Comparison with interleukin-13.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Both type I and type II interferons down-regulate human tumor necrosis factor receptors in human hepatocellular carcinoma cell line Hep G2. Role of protein kinase C.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Effect of cell cycle on the regulation of the cell surface and secreted forms of type I and type II human tumor necrosis factor receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Cell density-dependent regulation of cell surface expression of two types of human tumor necrosis factor receptors and its effect on cellular response

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Distinct roles of the two tumor necrosis factor (TNF) receptors in modulating TNF and lymphotoxin alpha effects

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

The p80 TNF receptor-associated kinase (p80TRAK) associates with residues 354-397 of the p80 cytoplasmic domain: similarity to casein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Specific activation of beta-casein kinase by the inflammatory cytokines interleukin 1 and tumour necrosis factor

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Specific detection of an interleukin 1- and tumour necrosis factor-activated beta-casein kinase in HeLa and KB cells

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Casein kinase-1 phosphorylates the p75 tumor necrosis factor receptor and negatively regulates tumor necrosis factor signaling for apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

A casein kinase I motif present in the cytoplasmic domain of members of the tumour necrosis factor ligand family is implicated in 'reverse signalling'

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

RIP and FADD: two "death domain"-containing proteins can induce apoptosis by convergent, but dissociable, pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Decreased sensitivity to tumour-necrosis factor but normal T-cell development in TNF receptor-2-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Crucial role of tumor necrosis factor (TNF) receptor 2 and membrane-bound TNF in experimental cerebral malaria.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Respective role of TNF receptors in the development of experimental cerebral malaria.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Tumour necrosis factor receptor II (p75) signalling is required for the migration of Langerhans' cells

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

A critical role of the p75 tumor necrosis factor receptor (p75TNF-R) in organ inflammation independent of TNF, lymphotoxin alpha, or the p55TNF-R.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

In vivo evidence for a functional role of both tumor necrosis factor (TNF) receptors and transmembrane TNF in experimental hepatitis

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Tumor necrosis factor receptor 2 plays a minor role for mycobacterial immunity.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

Tumour necrosis factor signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900262-5

7 January 2021

10.1016/S0898-6568(01)00262-5

Identifiers

DOI

1 reference

3 August 2017

1 reference

PubMed ID

11897488