Associations between UCP1 -3826A/G, UCP2 -866G/A, Ala55Val and Ins/Del, and UCP3 -55C/T polymorphisms and susceptibility to type 2 diabetes mellitus: case-control study and meta-analysis (Q34568272)

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English	Associations between UCP1 -3826A/G, UCP2 -866G/A, Ala55Val and Ins/Del, and UCP3 -55C/T polymorphisms and susceptibility to type 2 diabetes mellitus: case-control study and meta-analysis	scientific article

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23 February 2020

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Associations between UCP1 -3826A/G, UCP2 -866G/A, Ala55Val and Ins/Del, and UCP3 -55C/T polymorphisms and susceptibility to type 2 diabetes mellitus: case-control study and meta-analysis (English)

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23 February 2020

type 2 diabetes

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Cristiane Leitao

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23 February 2020

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23 February 2020

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Bianca M de Souza

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23 February 2020

Letícia A Brondani

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23 February 2020

Ana P Bouças

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23 February 2020

Denise A Sortica

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23 February 2020

Caroline K Kramer

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23 February 2020

Luís H Canani

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24 January 2013

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23 February 2020

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23 February 2020

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23 February 2020

e54259

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23 February 2020

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23 February 2020

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Creative Commons Attribution 4.0 International

24 January 2013

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April 2022 Public Data File from Crossref

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0 references

The role of the uncoupling protein 1 (UCP1) on the development of obesity and type 2 diabetes mellitus

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7 July 2018

The role of uncoupling protein 2 (UCP2) on the development of type 2 diabetes mellitus and its chronic complications

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7 July 2018

Genetic Variance in Uncoupling Protein 2 in Relation to Obesity, Type 2 Diabetes, and Related Metabolic Traits: Focus on the Functional -866G>A Promoter Variant (rs659366)

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7 July 2018

Uncoupling protein 2 and 3 gene polymorphisms and their association with type 2 diabetes in asian indians

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7 July 2018

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Association of the type 2 deiodinase Thr92Ala polymorphism with type 2 diabetes: case-control study and meta-analysis

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7 July 2018

Interaction between the UCP2 -866 G>A polymorphism, diabetes, and beta-blocker use among patients with acute coronary syndromes

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A haplotype at the UCP1 gene locus contributes to genetic risk for type 2 diabetes in Asian Indians (CURES-72).

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7 July 2018

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7 July 2018

Genomics of type 2 diabetes mellitus: implications for the clinician

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7 July 2018

The polymorphisms of UCP1 genes associated with fat metabolism, obesity and diabetes

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7 July 2018

The polymorphisms of UCP2 and UCP3 genes associated with fat metabolism, obesity and diabetes

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7 July 2018

Synthesis of genetic association studies for pertinent gene-disease associations requires appropriate methodological and statistical approaches

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7 July 2018

Genetic variants in the UCP2-UCP3 gene cluster and risk of diabetes in the Women's Health Initiative Observational Study.

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7 July 2018

The uncoupling protein 1 gene, UCP1, is expressed in mammalian islet cells and associated with acute insulin response to glucose in African American families from the IRAS Family Study

1 reference

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7 July 2018

Beta2-adrenergic receptor and UCP3 variants modulate the relationship between age and type 2 diabetes mellitus

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7 July 2018

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7 July 2018

Expression modification of uncoupling proteins and MnSOD in retinal endothelial cells and pericytes induced by high glucose: the role of reactive oxygen species in diabetic retinopathy

1 reference

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7 July 2018

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7 July 2018

Uncoupling protein 2 promoter polymorphism -866G/A affects its expression in beta-cells and modulates clinical profiles of Japanese type 2 diabetic patients

1 reference

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7 July 2018

Mutational analysis of the UCP2 core promoter and relationships of variants with obesity

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7 July 2018

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7 July 2018

A functional polymorphism in the promoter of UCP2 enhances obesity risk but reduces type 2 diabetes risk in obese middle-aged humans.

1 reference

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7 July 2018

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7 July 2018

Uncoupling proteins--a new family of proteins with unknown function

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7 July 2018

Uncoupling proteins: functional characteristics and role in the pathogenesis of obesity and Type II diabetes

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7 July 2018

A polymorphism in the 5' untranslated region and a Met229-->Leu variant in exon 5 of the human UCP1 gene are associated with susceptibility to type II diabetes mellitus

1 reference

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7 July 2018

Evidence for gene-nutrient interaction at the PPARgamma locus.

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7 July 2018

The human uncoupling protein-3 gene promoter requires MyoD and is induced by retinoic acid in muscle cells

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7 July 2018

The uncoupling protein-3 gene is transcribed from tissue-specific promoters in humans but not in rodents

1 reference

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7 July 2018

Cloning and characterization of the 5' flanking region of the human uncoupling protein 3 (UCP3) gene

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7 July 2018

Association between uncoupling protein polymorphisms (UCP2-UCP3) and energy metabolism/obesity in Pima indians.

1 reference

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7 July 2018

The fatty acid-binding protein-2 A54T polymorphism is associated with renal disease in patients with type 2 diabetes.

1 reference

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21 January 2018

Polymorphisms of the UCP2 gene are associated with proliferative diabetic retinopathy in patients with diabetes mellitus.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0054259

21 January 2018

Association of -3826 G variant in uncoupling protein-1 with increased BMI in overweight Australian women.

1 reference

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21 January 2018

An uncoupling protein 3 gene polymorphism associated with a lower risk of developing Type II diabetes and with atherogenic lipid profile in a French cohort

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0054259

21 January 2018

The -866A/A genotype in the promoter of the human uncoupling protein 2 gene is associated with insulin resistance and increased risk of type 2 diabetes.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0054259

21 January 2018

A common polymorphism of uncoupling protein 2 gene is associated with hypertension.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0054259

21 January 2018

Uncoupling protein-2 polymorphisms in type 2 diabetes, obesity, and insulin secretion

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0054259

21 January 2018

The common -866G/A polymorphism in the promoter region of the UCP-2 gene is associated with reduced risk of type 2 diabetes in Caucasians from Italy

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0054259

21 January 2018

The uncoupling protein 2 Ala55Val polymorphism is associated with diabetes mellitus: the CARDIA study

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0054259

21 January 2018

Ala55Val polymorphism on UCP2 gene predicts greater weight loss in morbidly obese patients undergoing gastric banding.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0054259

21 January 2018

Association of the ins/del polymorphisms of uncoupling protein 2 (UCP2) with BMI in a Korean population

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0054259

21 January 2018

Putative role of polymorphisms in UCP1-3 genes for diabetic nephropathy.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0054259

21 January 2018

The common -55 C/T polymorphism in the promoter region of the uncoupling protein 3 gene reduces prevalence of obesity and elevates serum high-density lipoprotein cholesterol levels in the general Japanese population

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0054259

21 January 2018

Linkage and association analyses of the UCP3 gene with obesity phenotypes in Caucasian families

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0054259

21 January 2018

Uncoupling protein 1 and 3 polymorphisms are associated with waist-to-hip ratio.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0054259

21 January 2018

Interactions between physical activity and variants of the genes encoding uncoupling proteins -2 and -3 in relation to body weight changes during a 10-y follow-up.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0054259

21 January 2018

A novel polymorphism in the proximal UCP3 promoter region: effect on skeletal muscle UCP3 mRNA expression and obesity in male non-diabetic Pima Indians

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0054259

21 January 2018

Skeletal muscle uncoupling protein 3 expression is a determinant of energy expenditure in Pima Indians.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0054259

21 January 2018

UCP2 -866G/A and Ala55Val, and UCP3 -55C/T polymorphisms in association with type 2 diabetes susceptibility: a meta-analysis study.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0054259

21 January 2018

[Common variants in beta 3-adrenergic-receptor and uncoupling protein-2 genes are associated with type 2 diabetes and obesity].

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554780

27 October 2018

Multifactor-dimensionality reduction shows a two-locus interaction associated with Type 2 diabetes mellitus.

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554780

27 October 2018

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0054259

21 January 2018

Lack of association between the uncoupling protein-2 Ala55Val gene polymorphism and phenotypic features of the Metabolic Syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554780

27 October 2018

Association between obesity and insulin resistance with UCP2–UCP3 gene variants in Spanish children and adolescents

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0054259

21 January 2018

Variation in the UCP2-UCP3 gene cluster predicts the development of type 2 diabetes in healthy middle-aged men

1 reference

https://pubmed.ncbi.nlm.nih.gov/23365654

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impact of the v/v 55 polymorphism of the uncoupling protein 2 gene on 24-h energy expenditure and substrate oxidation

1 reference

https://pubmed.ncbi.nlm.nih.gov/23365654

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The UCP1 gene polymorphism A-3826G in relation to DM2 and body composition in Czech population

1 reference

https://pubmed.ncbi.nlm.nih.gov/23365654

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synergistic effect of polymorphisms in uncoupling protein 1 and β3-adrenergic receptor genes on long-term body weight change in Finnish type 2 diabetic and non-diabetic control subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/23365654

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A genetic variation in the 5' flanking region of the UCP3 gene is associated with body mass index in humans in interaction with physical activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/23365654

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The uncoupling protein 3 -55 C -->T variant is not associated with Type II diabetes mellitus in Danish subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/23365654

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Association between polymorphism in uncoupling proteins and type 2 diabetes in a northwestern Colombian population]

1 reference

https://pubmed.ncbi.nlm.nih.gov/23365654

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Screening for variants of the uncoupling protein 2 gene in Japanese patients with non-insulin-dependent diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/23365654

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The association between the val/ala-55 polymorphism of the uncoupling protein 2 gene and exercise efficiency

1 reference

https://pubmed.ncbi.nlm.nih.gov/23365654

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association study of the -866G/A UCP2 gene promoter polymorphism with type 2 diabetes and obesity in a Tehran population: a case control study

1 reference

https://pubmed.ncbi.nlm.nih.gov/23365654

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular screening of uncoupling protein 2 gene in patients with noninsulin-dependent diabetes mellitus or obesity

1 reference

https://pubmed.ncbi.nlm.nih.gov/23365654

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1371/JOURNAL.PONE.0054259

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23 February 2020

2013PLoSO...854259D

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23 February 2020

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23 February 2020

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