The role of uncoupling protein 2 (UCP2) on the development of type 2 diabetes mellitus and its chronic complications (Q37903726)

25 August 2017

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title

The role of uncoupling protein 2 (UCP2) on the development of type 2 diabetes mellitus and its chronic complications (English)

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25 August 2017

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Bianca Marmontel de Souza

1

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25 August 2017

Taís Silveira Assmann

2

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25 August 2017

Lúcia Maria Kliemann

3

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25 August 2017

Jorge Luiz Gross

4

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25 August 2017

Luís Henrique Canani

5

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25 August 2017

Daisy Crispim

6

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25 August 2017

1 June 2011

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Arquivos Brasileiros de Endocrinologia e Metabologia

25 August 2017

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25 August 2017

55

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25 August 2017

4

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25 August 2017

239-248

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Multicenter study of the prevalence of diabetes mellitus and impaired glucose tolerance in the urban Brazilian population aged 30-69 yr. The Brazilian Cooperative Group on the Study of Diabetes Prevalence

25 August 2017

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302011000400001

Diagnosis and Classification of Diabetes Mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302011000400001

21 January 2018

Retinopathy in diabetes

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302011000400001

Uncoupling proteins, dietary fat and the metabolic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302011000400001

Mitochondrial uncoupling proteins--what is their physiological role?

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302011000400001

Uncoupling proteins: functional characteristics and role in the pathogenesis of obesity and Type II diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302011000400001

Reactive oxygen species, mitochondria, apoptosis and aging.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302011000400001

Mitochondrial dysfunction in insulin insensitivity: implication of mitochondrial role in type 2 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302011000400001

Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302011000400001

Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302011000400001

Decreased insulin-stimulated ATP synthesis and phosphate transport in muscle of insulin-resistant offspring of type 2 diabetic parents

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302011000400001

Mitochondrial dysfunction and type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302011000400001

Uncoupling proteins--a new family of proteins with unknown function

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302011000400001

Expression modification of uncoupling proteins and MnSOD in retinal endothelial cells and pericytes induced by high glucose: the role of reactive oxygen species in diabetic retinopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302011000400001

The uncoupling protein 1 gene, UCP1, is expressed in mammalian islet cells and associated with acute insulin response to glucose in African American families from the IRAS Family Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302011000400001

Uncoupling protein 2 and islet function

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302011000400001

Uncoupling protein-2: a novel gene linked to obesity and hyperinsulinemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302011000400001

The mitochondrial uncoupling-protein homologues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302011000400001

On the role of uncoupling protein-2 in pancreatic beta cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302011000400001

The regulation and turnover of mitochondrial uncoupling proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302011000400001

The reactions catalysed by the mitochondrial uncoupling proteins UCP2 and UCP3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302011000400001

Links between fatty acids and expression of UCP2 and UCP3 mRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302011000400001

Uncoupling protein-2 negatively regulates insulin secretion and is a major link between obesity, beta cell dysfunction, and type 2 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302011000400001

Disruption of the uncoupling protein-2 gene in mice reveals a role in immunity and reactive oxygen species production

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302011000400001

Superoxide-mediated activation of uncoupling protein 2 causes pancreatic beta cell dysfunction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302011000400001

Overexpression of uncoupling protein 2 inhibits glucose-stimulated insulin secretion from rat islets.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302011000400001

Dietary fatty acids Up-regulate the expression of UCP2 in 3T3-L1 preadipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302011000400001

The on-off switches of the mitochondrial uncoupling proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302011000400001

Mitochondrial superoxide: production, biological effects, and activation of uncoupling proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302011000400001

Uncoupling protein 2 promoter polymorphism -866G/A affects its expression in beta-cells and modulates clinical profiles of Japanese type 2 diabetic patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302011000400001

An uncoupling protein 2 gene variant is associated with a raised body mass index but not Type II diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302011000400001

The uncoupling protein 2 Ala55Val polymorphism is associated with diabetes mellitus: the CARDIA study

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302011000400001

The -866A/A genotype in the promoter of the human uncoupling protein 2 gene is associated with insulin resistance and increased risk of type 2 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302011000400001

The common -866G/A polymorphism in the promoter region of the UCP-2 gene is associated with reduced risk of type 2 diabetes in Caucasians from Italy

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302011000400001

A common polymorphism in the promoter of UCP2 contributes to the variation in insulin secretion in glucose-tolerant subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302011000400001

A functional polymorphism in the promoter of UCP2 enhances obesity risk but reduces type 2 diabetes risk in obese middle-aged humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302011000400001

Uncoupling protein-2 polymorphisms in type 2 diabetes, obesity, and insulin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302011000400001

Mutational analysis of the UCP2 core promoter and relationships of variants with obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302011000400001

Lack of association between the uncoupling protein-2 Ala55Val gene polymorphism and phenotypic features of the Metabolic Syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302011000400001

Genetic variants in the UCP2-UCP3 gene cluster and risk of diabetes in the Women's Health Initiative Observational Study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302011000400001

Mitochondrial uncoupling protein gene cluster variation (UCP2-UCP3) and the risk of incident type 2 diabetes mellitus: the Women's Genome Health Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302011000400001

A common polymorphism in the promoter of UCP2 is associated with decreased risk of obesity in middle-aged humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302011000400001

The polymorphisms of UCP2 and UCP3 genes associated with fat metabolism, obesity and diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302011000400001

Associations of the UCP2 gene locus with asymptomatic carotid atherosclerosis in middle-aged women.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302011000400001

Putative role of polymorphisms in UCP1-3 genes for diabetic nephropathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302011000400001

Polymorphisms of the UCP2 gene are associated with proliferative diabetic retinopathy in patients with diabetes mellitus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302011000400001

Association between uncoupling protein polymorphisms (UCP2-UCP3) and energy metabolism/obesity in Pima indians.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302011000400001

The emerging functions of UCP2 in health, disease, and therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302011000400001

The common -866G>A variant in the promoter of UCP2 is associated with decreased risk of coronary artery disease in type 2 diabetic men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302011000400001

Uncoupling Protein-2 Participates in Cellular Defense against Oxidative Stress in Clonal β-Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302011000400001

Association between obesity and insulin resistance with UCP2–UCP3 gene variants in Spanish children and adolescents

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302011000400001

10.1590/S0004-27302011000400001

21 January 2018

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DOI

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25 August 2017

1 reference