Targeted deletion of p53 in the proximal tubule prevents ischemic renal injury (Q34568811)

3 August 2017

Targeted deletion of p53 in the proximal tubule prevents ischemic renal injury (English)

1 reference

3 August 2017

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24854277%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

author name string

Yuan Ying

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24854277%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Sherry N Westphal

3

1 reference

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4 June 2020

Kelly E Long

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24854277%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Babu J Padanilam

5

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4 June 2020

publication date

22 May 2014

1 reference

Journal of the American Society of Nephrology

3 August 2017

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4 June 2020

volume

25

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4 June 2020

issue

12

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4 June 2020

page(s)

2707-2716

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describes a project that uses

4 June 2020

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4243356/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Bax and Bak function as the outer membrane component of the mitochondrial permeability pore in regulating necrotic cell death in mice

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Two independent pathways of regulated necrosis mediate ischemia-reperfusion injury

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p53 regulates a non-apoptotic death induced by ROS.

7 July 2018

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Bax and Bak have critical roles in ischemic acute kidney injury in global and proximal tubule-specific knockout mouse models

7 July 2018

1 reference

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p53 is renoprotective after ischemic kidney injury by reducing inflammation.

7 July 2018

1 reference

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Specific deletion of glycogen synthase kinase-3β in the renal proximal tubule protects against acute nephrotoxic injury in mice

7 July 2018

1 reference

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p53 opens the mitochondrial permeability transition pore to trigger necrosis

7 July 2018

1 reference

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Bax regulates primary necrosis through mitochondrial dynamics

7 July 2018

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The p53 inhibitor pifithrin-α can stimulate fibrosis in a rat model of ischemic acute kidney injury.

7 July 2018

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Loss of poly(ADP-ribose) polymerase 1 attenuates renal fibrosis and inflammation during unilateral ureteral obstruction.

7 July 2018

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p53 target Siva regulates apoptosis in ischemic kidneys

7 July 2018

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Epithelial cell cycle arrest in G2/M mediates kidney fibrosis after injury

7 July 2018

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Activation of p53 promotes renal injury in acute aristolochic acid nephropathy

7 July 2018

1 reference

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siRNA targeted to p53 attenuates ischemic and cisplatin-induced acute kidney injury

7 July 2018

1 reference

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7 July 2018

Modes of p53 regulation

1 reference

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Compartmentalization of neutrophils in the kidney and lung following acute ischemic kidney injury

7 July 2018

1 reference

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The BCL-2 protein family: opposing activities that mediate cell death

7 July 2018

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Activation and involvement of p53 in cisplatin-induced nephrotoxicity

7 July 2018

1 reference

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p53 in health and disease

7 July 2018

1 reference

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Renal cyst development in mice with conditional inactivation of the von Hippel-Lindau tumor suppressor

7 July 2018

1 reference

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Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243356

Recent advances in the pathophysiology of ischemic acute renal failure

7 July 2018

1 reference

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Guanosine supplementation reduces apoptosis and protects renal function in the setting of ischemic injury

7 July 2018

1 reference

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Poly(ADP-ribose) polymerase is a mediator of necrotic cell death by ATP depletion

7 July 2018

1 reference

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Intercellular adhesion molecule-1-deficient mice are protected against ischemic renal injury

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243356

Cloning of cDNAs for M-phase phosphoproteins recognized by the MPM2 monoclonal antibody and determination of the phosphorylated epitope

7 July 2018

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cdc25 is one of the MPM-2 antigens involved in the activation of maturation-promoting factor

7 July 2018

1 reference

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Outer medullary circulatory defect in ischemic acute renal failure.

7 July 2018

1 reference

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Poly(ADP-ribose) polymerase 1 activation is required for cisplatin nephrotoxicity.

7 July 2018

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Cyclophilin D gene ablation protects mice from ischemic renal injury.

27 October 2018

1 reference

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PARP-1 inhibits glycolysis in ischemic kidneys

27 October 2018

1 reference

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Sequential activation of poly(ADP-ribose) polymerase 1, calpains, and Bax is essential in apoptosis-inducing factor-mediated programmed necrosis.

27 October 2018

1 reference

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Selective sphingosine 1-phosphate 1 receptor activation reduces ischemia-reperfusion injury in mouse kidney

27 October 2018

1 reference

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Aquaporin-1 facilitates epithelial cell migration in kidney proximal tubule.

27 October 2018

1 reference

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Bid deficiency ameliorates ischemic renal failure and delays animal death in C57BL/6 mice

27 October 2018

1 reference

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Caspase-1-deficient mice are protected against cisplatin-induced apoptosis and acute tubular necrosis

27 October 2018

1 reference

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Poly(ADP-ribose) polymerase-1 gene ablation protects mice from ischemic renal injury

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243356

Activation of protein kinase C isozymes protects LLCPK1 cells from H2O2 induced necrotic cell death

27 October 2018

1 reference

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Prevention of apoptotic and necrotic cell death, caspase-3 activation, and renal dysfunction by melatonin after ischemia/reperfusion

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243356

P53 mediates the apoptotic response to GTP depletion after renal ischemia-reperfusion: protective role of a p53 inhibitor

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243356

pEg2 aurora-A kinase, histone H3 phosphorylation, and chromosome assembly in Xenopus egg extract

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243356

Inhibition of poly(ADP-ribose) polymerase attenuates ischemic renal injury in rats

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243356

Ischemic damage and repair in the rat proximal tubule: differences among the S1, S2, and S3 segments

27 October 2018

1 reference

12 December 2020

The morphology of "acute tubular necrosis" in man: analysis of 57 renal biopsies and a comparison with the glycerol model

1 reference

12 December 2020

Role of the medullary perfusion defect in the pathogenesis of ischemic renal failure

1 reference

12 December 2020

Epidemiology of acute renal failure: a prospective, multicenter, community-based study. Madrid Acute Renal Failure Study Group

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12 December 2020

Outcomes in acute renal failure

1 reference

12 December 2020

Adenovirus-mediated bcl-2 gene transfer inhibits renal ischemia/reperfusion induced tubular oxidative stress and apoptosis

1 reference

12 December 2020

Identifiers

DOI

10.1681/ASN.2013121270

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24854277%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24854277%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

1 reference