Rosiglitazone causes cardiotoxicity via peroxisome proliferator-activated receptor γ-independent mitochondrial oxidative stress in mouse hearts (Q34569388)

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English	Rosiglitazone causes cardiotoxicity via peroxisome proliferator-activated receptor γ-independent mitochondrial oxidative stress in mouse hearts	scientific article

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scholarly article

1 reference

Europe PubMed Central

3 August 2017

Rosiglitazone causes cardiotoxicity via peroxisome proliferator-activated receptor γ-independent mitochondrial oxidative stress in mouse hearts (English)

1 reference

Europe PubMed Central

3 August 2017

(RS)-rosiglitazone

1 reference

based on heuristic

inferred from title

author name string

Huamei He

1

1 reference

Europe PubMed Central

3 August 2017

Hai Tao

2

1 reference

Europe PubMed Central

3 August 2017

Hui Xiong

3

1 reference

Europe PubMed Central

3 August 2017

Sheng Zhong Duan

4

1 reference

Europe PubMed Central

3 August 2017

Francis X McGowan

5

1 reference

Europe PubMed Central

3 August 2017

Richard M Mortensen

6

1 reference

Europe PubMed Central

3 August 2017

James A Balschi

7

1 reference

Europe PubMed Central

3 August 2017

publication date

21 January 2014

1 reference

Europe PubMed Central

3 August 2017

Toxicological Sciences

1 reference

Europe PubMed Central

3 August 2017

138

1 reference

Europe PubMed Central

3 August 2017

2

1 reference

Europe PubMed Central

3 August 2017

468-481

1 reference

Europe PubMed Central

3 August 2017

Mitochondria as a source of reactive oxygen and nitrogen species: from molecular mechanisms to human health

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243497

7 July 2018

Chemical proteomics-based analysis of off-target binding profiles for rosiglitazone and pioglitazone: clues for assessing potential for cardiotoxicity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243497

7 July 2018

Mitochondria as a source and target of lipid peroxidation products in healthy and diseased heart

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243497

7 July 2018

Peroxisome proliferator-activated receptor {delta} is an essential transcriptional regulator for mitochondrial protection and biogenesis in adult heart

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243497

7 July 2018

Peroxisome proliferator-activated receptor gamma-independent effects of thiazolidinediones on human cardiac myofibroblast function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243497

7 July 2018

Troglitazone, but not rosiglitazone, damages mitochondrial DNA and induces mitochondrial dysfunction and cell death in human hepatocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243497

7 July 2018

Type 2 diabetes, thiazolidinediones, and cardiovascular risk

1 reference

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7 July 2018

Effects of chronic PPAR-agonist treatment on cardiac structure and function, blood pressure, and kidney in healthy sprague-dawley rats

1 reference

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7 July 2018

Comparison of cardiovascular outcomes in elderly patients with diabetes who initiated rosiglitazone vs pioglitazone therapy

1 reference

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7 July 2018

Energy metabolism in heart failure and remodelling

1 reference

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7 July 2018

Rosiglitazone Suppresses the Growth and Invasiveness of SGC-7901 Gastric Cancer Cells and Angiogenesis In Vitro via PPARgamma Dependent and Independent Mechanisms

1 reference

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7 July 2018

The peroxisome proliferator-activated receptor-gamma agonist pioglitazone represses inflammation in a peroxisome proliferator-activated receptor-alpha-dependent manner in vitro and in vivo in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243497

7 July 2018

Redox regulation of cell survival

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243497

7 July 2018

Congestive heart failure and cardiovascular death in patients with prediabetes and type 2 diabetes given thiazolidinediones: a meta-analysis of randomised clinical trials

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243497

7 July 2018

Long-term risk of cardiovascular events with rosiglitazone: a meta-analysis

1 reference

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7 July 2018

Cardiomyocyte expression of PPARgamma leads to cardiac dysfunction in mice

1 reference

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7 July 2018

Effects of rosiglitazone on the liver histology and mitochondrial function in ob/ob mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243497

7 July 2018

Rosiglitazone evaluated for cardiovascular outcomes--an interim analysis

1 reference

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7 July 2018

R-92L and R-92W mutations in cardiac troponin T lead to distinct energetic phenotypes in intact mouse hearts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243497

7 July 2018

Effect of Rosiglitazone on the Risk of Myocardial Infarction and Death from Cardiovascular Causes

1 reference

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7 July 2018

Anti-proliferative effect of peroxisome proliferator-activated receptor gamma agonists on human malignant melanoma cells in vitro

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7 July 2018

Role of PPAR- gamma agonist thiazolidinediones in treatment of pre-diabetic and diabetic individuals: a cardiovascular perspective.

1 reference

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7 July 2018

Pleiotropic effects of thiazolidinediones: taking a look beyond antidiabetic activity.

1 reference

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7 July 2018

The antidiabetic agent rosiglitazone upregulates SERCA2 and enhances TNF-alpha- and LPS-induced NF-kappaB-dependent transcription and TNF-alpha-induced IL-6 secretion in ventricular myocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243497

7 July 2018

PPAR-gamma activation fails to provide myocardial protection in ischemia and reperfusion in pigs.

1 reference

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7 July 2018

Thiazolidinediones

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7 July 2018

Mitochondrial respiratory chain dysfunction, a non-receptor-mediated effect of synthetic PPAR-ligands: biochemical and pharmacological implications

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7 July 2018

Evidence for a potent antiinflammatory effect of rosiglitazone

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7 July 2018

Women and heart disease: the role of diabetes and hyperglycemia

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7 July 2018

Thiazolidinedione use, fluid retention, and congestive heart failure: a consensus statement from the American Heart Association and American Diabetes Association. October 7, 2003.

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7 July 2018

Essential role of the NADPH oxidase subunit p47(phox) in endothelial cell superoxide production in response to phorbol ester and tumor necrosis factor-alpha

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7 July 2018

PPAR signaling in the control of cardiac energy metabolism

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7 July 2018

High phosphorylation efficiency and depression of uncoupled respiration in mitochondria under hypoxia.

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7 July 2018

Mitochondrial dysfunction and oxidative stress in aging and neurodegenerative disease

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7 July 2018

Peroxisome proliferator-activated receptors in the cardiovascular system

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7 July 2018

Cardiovascular disease in the diabetic woman

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7 July 2018

Thiazolidinediones: a new class of antidiabetic drugs

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7 July 2018

Cardiac and glycemic benefits of troglitazone treatment in NIDDM. The Troglitazone Study Group.

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7 July 2018

Oxidative stress and mitochondrial dysfunction in neurodegeneration.

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7 July 2018

Microassay of free and total creatine from tissue extracts by combination of chromatographic and fluorometric methods

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7 July 2018

Rosiglitazone increases fatty acid oxidation and fatty acid translocase (FAT/CD36) but not carnitine palmitoyltransferase I in rat muscle mitochondria

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21 January 2018

Rosiglitazone stimulates nitric oxide synthesis in human aortic endothelial cells via AMP-activated protein kinase.

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21 January 2018

Thiazolidinediones, like metformin, inhibit respiratory complex I: a common mechanism contributing to their antidiabetic actions?

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21 January 2018

Rosiglitazone reduces glucose-induced oxidative stress mediated by NAD(P)H oxidase via AMPK-dependent mechanism.

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21 January 2018

A randomized, placebo-controlled trial assessing the effects of rosiglitazone on echocardiographic function and cardiac status in type 2 diabetic patients with New York Heart Association Functional Class I or II Heart Failure.

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21 January 2018

Cardiomyocyte-specific knockout and agonist of peroxisome proliferator-activated receptor-gamma both induce cardiac hypertrophy in mice

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21 January 2018

Peroxisome proliferator-activated receptor gamma-independent activation of p38 MAPK by thiazolidinediones involves calcium/calmodulin-dependent protein kinase II and protein kinase R: correlation with endoplasmic reticulum stress

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21 January 2018

Rosiglitazone suppresses human lung carcinoma cell growth through PPARgamma-dependent and PPARgamma-independent signal pathways

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The PPARgamma ligand, rosiglitazone, reduces vascular oxidative stress and NADPH oxidase expression in diabetic mice.

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The effects of rosiglitazone on oxidative stress and lipid profile in left ventricular muscles of diabetic rats.

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Mechanisms responsible for beneficial and adverse effects of rosiglitazone in a rat model of acute cardiac ischaemia-reperfusion.

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Effect of rosiglitazone on cardiac electrophysiology, infarct size and mitochondrial function in ischaemia and reperfusion of swine and rat heart.

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21 January 2018

Opposite effects of pioglitazone and rosiglitazone on mitochondrial respiration in skeletal muscle of patients with type 2 diabetes.

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21 January 2018

Countervailing vascular effects of rosiglitazone in high cardiovascular risk mice: role of oxidative stress and PRMT-1.

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Thiazolidinediones and Heart Failure: A teleo-analysis

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A comparison of the effects of rosiglitazone and glyburide on cardiovascular function and glycemic control in patients with type 2 diabetes

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21 January 2018

Rosiglitazone, but not glimepiride, improves myocardial diastolic function in association with reduction in oxidative stress in type 2 diabetic patients without overt heart disease

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21 January 2018

Rosiglitazone (Avandia): hepatic, cardiac and hematological reactions

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27 October 2018

Effect of rosiglitazone on N-nitroso-N-methylurea-induced mammary tumors in rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/24449420

12 December 2020

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Mitochondria are an early target of oxidative modifications in senescing legume nodules

1 reference

https://pubmed.ncbi.nlm.nih.gov/24449420

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cardiac hypertrophy caused by peroxisome proliferator- activated receptor-gamma agonist treatment occurs independently of changes in myocardial insulin signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/24449420

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Critical role of monocyte chemoattractant protein-1/CC chemokine ligand 2 in the pathogenesis of ischemic cardiomyopathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/24449420

12 December 2020

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RETRACTED: Rosiglitazone and pioglitazone aggravate doxorubicin-induced cardiomyopathy in Wistar rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/24449420

12 December 2020

based on heuristic

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Adjudication of serious heart failure in patients from PROactive

1 reference

https://pubmed.ncbi.nlm.nih.gov/24449420

12 December 2020

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Identifiers

10.1093/TOXSCI/KFU015

1 reference

Europe PubMed Central

3 August 2017

1 reference

Europe PubMed Central

3 August 2017

1 reference

Europe PubMed Central

3 August 2017

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