Helper T cell IL-2 production is limited by negative feedback and STAT-dependent cytokine signals. (Q34574100)

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24 December 2019

title

Helper T cell IL-2 production is limited by negative feedback and STAT-dependent cytokine signals (English)

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24 December 2019

1

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24 December 2019

Lothar Hennighausen

6

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24 December 2019

author name string

Cristina M Tato

2

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24 December 2019

Jason S Stumhofer

3

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24 December 2019

Zhengju Yao

4

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24 December 2019

Yongzhi K Cui

5

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24 December 2019

John J O'Shea

7

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24 December 2019

Christopher A Hunter

8

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24 December 2019

language of work or name

English

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publication date

16 January 2007

1 reference

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Journal of Experimental Medicine

24 December 2019

published in

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24 December 2019

volume

204

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24 December 2019

issue

1

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24 December 2019

page(s)

65-71

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Interleukin-2 signals during priming are required for secondary expansion of CD8+ memory T cells.

24 December 2019

cites work

1 reference

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Stat5a/b are essential for normal lymphoid development and differentiation

7 July 2018

1 reference

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IL-27 limits IL-2 production during Th1 differentiation.

7 July 2018

1 reference

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Sequential development of interleukin 2-dependent effector and regulatory T cells in response to endogenous systemic antigen

7 July 2018

1 reference

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IL-2 production in developing Th1 cells is regulated by heterodimerization of RelA and T-bet and requires T-bet serine residue 508.

7 July 2018

1 reference

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New IL-12-family members: IL-23 and IL-27, cytokines with divergent functions

7 July 2018

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7 July 2018

The B7 family revisited

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IL-7: maintaining T-cell memory and achieving homeostasis

7 July 2018

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Tolerance, not immunity, crucially depends on IL-2.

7 July 2018

1 reference

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Cytokines and immunodeficiency diseases

7 July 2018

1 reference

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Tob is a negative regulator of activation that is expressed in anergic and quiescent T cells

7 July 2018

1 reference

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In vivo priming of CD4 T cells that produce interleukin (IL)-2 but not IL-4 or interferon (IFN)-gamma, and can subsequently differentiate into IL-4- or IFN-gamma-secreting cells

7 July 2018

1 reference

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Contrasting roles of IL-2 and IL-15 in the life and death of lymphocytes: implications for immunotherapy

7 July 2018

1 reference

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The interleukin-4 receptor activates STAT5 by a mechanism that relies upon common gamma-chain

7 July 2018

1 reference

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Interleukin 4 suppresses interleukin 2 and interferon gamma production by naive T cells stimulated by accessory cell-dependent receptor engagement

7 July 2018

1 reference

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Transcriptional regulation of the IL-2 gene

7 July 2018

1 reference

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Purification and some characteristics of human T-cell growth factor from phytohemagglutinin-stimulated lymphocyte-conditioned media

7 July 2018

1 reference

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Control of biologically active interleukin 2 messenger RNA formation in induced human lymphocytes.

7 July 2018

1 reference

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Observations on the systemic administration of autologous lymphokine-activated killer cells and recombinant interleukin-2 to patients with metastatic cancer

7 July 2018

1 reference

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Interleukin-2: inception, impact, and implications

7 July 2018

1 reference

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NF-kappa B subunit regulation in nontransformed CD4+ T lymphocytes

7 July 2018

1 reference

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Interleukin-2 programs mouse alpha beta T lymphocytes for apoptosis

7 July 2018

1 reference

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Interleukin-2 induced immune effects in human immunodeficiency virus-infected patients receiving intermittent interleukin-2 immunotherapy

21 January 2018

1 reference

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IL-2 secretion by CD4+ T cells in vivo is rapid, transient, and influenced by TCR-specific competition.

21 January 2018

1 reference

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Selective, stable demethylation of the interleukin-2 gene enhances transcription by an active process

21 January 2018

1 reference

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Smad3 is essential for TGF-beta 1 to suppress IL-2 production and TCR-induced proliferation, but not IL-2-induced proliferation

21 January 2018

1 reference

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p27kip1 functions as an anergy factor inhibiting interleukin 2 transcription and clonal expansion of alloreactive human and mouse helper T lymphocytes

21 January 2018

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12 December 2020

T(H)1 and T(H)2 cells: a historical perspective

1 reference

12 December 2020

Stat5 activation plays a critical role in Th2 differentiation

1 reference

12 December 2020

Regulation of lymphokine messenger RNA stability by a surface-mediated T cell activation pathway

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.20061198

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17227909%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

1 reference

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24 December 2019

1 reference