Antidepressant-like effects of the novel, selective, 5-HT2C receptor agonist WAY-163909 in rodents (Q34575450)

3 August 2017

Antidepressant-like effects of the novel, selective, 5-HT2C receptor agonist WAY-163909 in rodents (English)

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3 August 2017

John F Cryan

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author name string

Sharon Rosenzweig-Lipson

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3 August 2017

Annmarie Sabb

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3 August 2017

Gary Stack

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3 August 2017

Paul Mitchell

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3 August 2017

Irwin Lucki

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3 August 2017

Jessica E Malberg

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3 August 2017

Steve Grauer

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3 August 2017

Julie Brennan

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3 August 2017

Stacey J Sukoff Rizzo

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3 August 2017

John Dunlop

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3 August 2017

James E Barrett

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3 August 2017

Karen L Marquis

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3 August 2017

13 February 2007

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192

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2

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159-170

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https://scigraph.springernature.com/pub.10.1007/s00213-007-0710-6

3 August 2017

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Chronic treatment with meta-chlorophenylpiperazine (m-CPP) alters behavioral and cerebral metabolic responses to the serotonin agonists m-CPP and quipazine but not 8-hydroxy-2(di-N-propylamino)tetralin.

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Selective serotonin re-uptake inhibitors decrease schedule-induced polydipsia in rats: a potential model for obsessive compulsive disorder

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Combining pindolol and paroxetine in an animal model of chronic antidepressant action--can early onset of action be detected?

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Antidepressant-like behavioral effects mediated by 5-Hydroxytryptamine(2C) receptors.

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5HT2C receptor agonists exhibit antidepressant-like properties in the anhedonia model of depression in rats

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Synthesis and 5-hydroxytryptamine (5-HT) activity of 2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5-(6H)ones and 2,3,4,4a,5,6-hexahydro-1H-pyrazino[1,2-a]quinoxalines

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Effects of housing, restraint and chronic treatments with mCPP and sertraline on behavioural responses to mCPP.

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Acute and chronic antidepressant drug treatments induce opposite effects in the social behaviour of rats.

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Differentiating antidepressants of the future: efficacy and safety

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Compulsive behavior in the 5-HT2C receptor knockout mouse

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Animal models of depressive illness: the importance of chronic drug treatment

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Antidepressants preferentially enhance habituation to novelty in the olfactory bulbectomized rat.

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12 December 2020

Anxiolytic-like actions of BW 723C86 in the rat Vogel conflict test are 5-HT2B receptor mediated

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12 December 2020

Antiobesity effect of YM348, a novel 5-HT2C receptor agonist, in Zucker rats

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12 December 2020

Involvement of 5-HT(2C) receptors in the anti-immobility effects of antidepressants in the forced swimming test in mice

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Depression: a new animal model sensitive to antidepressant treatments

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Effects of chronic fluoxetine treatment in the presence and absence of (+/-)pindolol: a microdialysis study

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Oral administration of the 5-HT2Creceptor agonist, mCPP, reduces body weight gain in rats over 28 days as a result of maintained hypophagia.

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Pharmacological profile of YM348, a novel, potent and orally active 5-HT2C receptor agonist

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A novel approach for predicting antidepressant-induced sexual dysfunction in rats

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12 December 2020

WAY-163909 [(7bR, 10aR)-1,2,3,4,8,9,10,10a-octahydro-7bH-cyclopenta-[b][1,4]diazepino[6,7,1hi]indole], a novel 5-hydroxytryptamine 2C receptor-selective agonist with anorectic activity

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12 December 2020

Inactivation of 5-HT(2C) receptors potentiates consequences of serotonin reuptake blockade

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12 December 2020

Novel agonists of 5HT2C receptors. Synthesis and biological evaluation of substituted 2-(indol-1-yl)-1-methylethylamines and 2-(indeno[1,2-b]pyrrol-1-yl)-1-methylethylamines. Improved therapeutics for obsessive compulsive disorder

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12 December 2020

WAY-163909 [(7bR,10aR)-1,2,3,4,8,9,10,10a-octahydro-7bH-cyclopenta-[b][1,4]diazepino[6,7,1hi]indole]: A novel 5-hydroxytryptamine 2C receptor-selective agonist with preclinical antipsychotic-like activity.

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12 December 2020

Onset of the effects of the 5-HT1A antagonist, WAY-100635, alone, and in combination with paroxetine, on olfactory bulbectomy and 8-OH-DPAT-induced changes in the rat.

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12 December 2020

Effects of repeated mild stress and two antidepressant treatments on the behavioral response to 5HT1C receptor activation in rats.

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12 December 2020

Activity and onset of action of reboxetine and effect of combination with sertraline in an animal model of depression.

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12 December 2020

Active behaviors in the rat forced swimming test differentially produced by serotonergic and noradrenergic antidepressants

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12 December 2020

Comparison of the effects of antidepressants on norepinephrine and serotonin concentrations in the rat frontal cortex: an in-vivo microdialysis study

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12 December 2020

Comparative effects of continuous infusion of mCPP, Ro 60-0175 and d-fenfluramine on food intake, water intake, body weight and locomotor activity in rats.

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12 December 2020

Antiobesity-like effects of the 5-HT2C receptor agonist WAY-161503.

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12 December 2020

Acceleration of onset of action in schedule-induced polydipsia: combinations of SSRI and 5-HT1A and 5-HT1B receptor antagonists

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12 December 2020

SB 242084, a selective and brain penetrant 5-HT2C receptor antagonist

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12 December 2020

Cycloalkyl[b][1,4]benzodiazepinoindoles are agonists at the human 5-HT2C receptor

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12 December 2020

The olfactory bulbectomized rat as a model of depression: an update

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12 December 2020

10.1007/S00213-007-0710-6

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3 August 2017

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