Cell-intrinsic transforming growth factor-beta signaling mediates virus-specific CD8+ T cell deletion and viral persistence in vivo (Q34577200)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19604493%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

title

Cell-intrinsic transforming growth factor-beta signaling mediates virus-specific CD8+ T cell deletion and viral persistence in vivo (English)

1 reference

2 February 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19604493%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

author name string

Victor Alcalde

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19604493%20AND%20SRC:MED&resulttype=core&format=json

2

1 reference

2 February 2020

Yating Yang

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19604493%20AND%20SRC:MED&resulttype=core&format=json

3

1 reference

2 February 2020

Karsten Sauer

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19604493%20AND%20SRC:MED&resulttype=core&format=json

4

1 reference

2 February 2020

Elina I Zuniga

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19604493%20AND%20SRC:MED&resulttype=core&format=json

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19604493%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

language of work or name

English

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publication date

1 July 2009

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2 February 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19604493%20AND%20SRC:MED&resulttype=core&format=json

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19604493%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

volume

31

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2 February 2020

page(s)

145-157

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2 February 2020

issue

1

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Chronic antigen stimulation alone is sufficient to drive CD8+ T cell exhaustion

2 February 2020

cites work

1 reference

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Multiple-cytokine-producing antiviral CD4 T cells are functionally superior to single-cytokine-producing cells

7 July 2018

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Hepatitis C Virus (HCV)-Specific CD8+ Cells Produce Transforming Growth Factor That Can Suppress HCV-Specific T-Cell Responses

7 July 2018

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7 July 2018

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7 July 2018

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Liver-Infiltrating Lymphocytes in Chronic Human Hepatitis C Virus Infection Display an Exhausted Phenotype with High Levels of PD-1 and Low Levels of CD127 Expression

7 July 2018

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Cellular mechanisms of fatal early-onset autoimmunity in mice with the T cell-specific targeting of transforming growth factor-beta receptor

7 July 2018

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Transforming growth factor-beta controls development, homeostasis, and tolerance of T cells by regulatory T cell-dependent and -independent mechanisms

7 July 2018

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PD-1 Expression in Acute Hepatitis C Virus (HCV) Infection Is Associated with HCV-Specific CD8 Exhaustion

7 July 2018

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PD-1 is a regulator of virus-specific CD8+ T cell survival in HIV infection

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Viral persistence alters CD8 T-cell immunodominance and tissue distribution and results in distinct stages of functional impairment

7 July 2018

1 reference

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Making sense of latent TGFbeta activation

7 July 2018

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HIV antigens can induce TGF-beta(1)-producing immunoregulatory CD8+ T cells

7 July 2018

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Critical role for alpha/beta and gamma interferons in persistence of lymphocytic choriomeningitis virus by clonal exhaustion of cytotoxic T cells

7 July 2018

1 reference

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TGF-beta in the cardiovascular system: molecular mechanisms of a context-specific growth factor

7 July 2018

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Sustained Dysfunction of Antiviral CD8+ T Lymphocytes after Infection with Hepatitis C Virus

7 July 2018

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Impaired function of circulating HIV-specific CD8(+) T cells in chronic human immunodeficiency virus infection.

7 July 2018

1 reference

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Viral immune evasion due to persistence of activated T cells without effector function

7 July 2018

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7 July 2018

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Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death

7 July 2018

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7 July 2018

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7 July 2018

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Virus-induced immunosuppression: immune system-mediated destruction of virus-infected dendritic cells results in generalized immune suppression.

7 July 2018

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Molecular determinants of macrophage tropism and viral persistence: importance of single amino acid changes in the polymerase and glycoprotein of lymphocytic choriomeningitis virus

7 July 2018

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T4+ T helper cell function in vivo: differential requirement for induction of antiviral cytotoxic T-cell and antibody responses

7 July 2018

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Production of transforming growth factor beta by human T lymphocytes and its potential role in the regulation of T cell growth

7 July 2018

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A role for transforming growth factor-beta 1 in regulating natural killer cell and T lymphocyte proliferative responses during acute infection with lymphocytic choriomeningitis virus

7 July 2018

1 reference

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Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease

7 July 2018

1 reference

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TGF-beta in intestinal lymphoid organs contributes to the death of armed effector CD8 T cells and is associated with the absence of virus containment in rhesus macaques infected with the simian immunodeficiency virus

7 July 2018

1 reference

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T cells doing it for themselves: TGF-beta regulation of Th1 and Th17 cells

27 October 2018

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Blocking of interleukin-10 receptor--a novel approach to stimulate T-helper cell type 1 responses to hepatitis C virus

27 October 2018

1 reference

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Transforming growth factor beta3 induces cell death during the first stage of mammary gland involution.

27 October 2018

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Virus persistence in acutely infected immunocompetent mice by exhaustion of antiviral cytotoxic effector T cells

27 October 2018

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Selection of genetic variants of lymphocytic choriomeningitis virus in spleens of persistently infected mice. Role in suppression of cytotoxic T lymphocyte response and viral persistence

27 October 2018

1 reference

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Abrogation of TGFbeta signaling in T cells leads to spontaneous T cell differentiation and autoimmune disease

27 October 2018

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12 December 2020

Persistent numbers of tetramer+ CD8(+) T cells, but loss of interferon-gamma+ HIV-specific T cells during progression to AIDS

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12 December 2020

Endocrine expression of the active form of TGF-beta1 in the TGF-beta1 null mice fails to ameliorate lethal phenotype

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12 December 2020

NF-AT-mediated expression of TGF-beta1 in tolerant T cells

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12 December 2020

10.1016/J.IMMUNI.2009.06.015

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19604493%20AND%20SRC:MED&resulttype=core&format=json

release_6zyfavc76feh5oexqz3wy2xrfy

2 February 2020

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1 reference

Fatcat

https://api.fatcat.wiki/v0/release/6zyfavc76feh5oexqz3wy2xrfy

24 November 2022