A portable BRCA1-HAC (human artificial chromosome) module for analysis of BRCA1 tumor suppressor function. (Q34579790)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25260588%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

title

A portable BRCA1-HAC (human artificial chromosome) module for analysis of BRCA1 tumor suppressor function (English)

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20 February 2020

3

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20 February 2020

William Charles Earnshaw

6

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20 February 2020

author name string

Artem V Kononenko

1

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20 February 2020

Ruchi Bansal

2

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20 February 2020

Brenda R Grimes

4

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20 February 2020

Hiroshi Masumoto

5

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20 February 2020

Vladimir Larionov

7

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20 February 2020

Natalay Kouprina

8

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20 February 2020

language of work or name

English

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publication date

26 September 2014

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20 February 2020

published in

Nucleic Acids Research

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20 February 2020

volume

42

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20 February 2020

issue

21

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Centromere reference models for human chromosomes X and Y satellite arrays.

20 February 2020

page(s)

e164-e164

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cites work

1 reference

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7 July 2018

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Interaction between DNA Polymerase β and BRCA1

7 July 2018

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A new assay for measuring chromosome instability (CIN) and identification of drugs that elevate CIN in cancer cells

7 July 2018

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Re-engineering an alphoid(tetO)-HAC-based vector to enable high-throughput analyses of gene function

7 July 2018

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Organization of synthetic alphoid DNA array in human artificial chromosome (HAC) with a conditional centromere

7 July 2018

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The role of epigenetic transcriptional regulation in BRCA1-mediated tumor suppression

7 July 2018

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A new generation of human artificial chromosomes for functional genomics and gene therapy

7 July 2018

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HACking the centromere chromatin code: insights from human artificial chromosomes.

7 July 2018

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Heterochromatin instability in cancer: from the Barr body to satellites and the nuclear periphery

7 July 2018

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Breaking the HAC Barrier: histone H3K9 acetyl/methyl balance regulates CENP-A assembly

7 July 2018

1 reference

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Epigenetic engineering: histone H3K9 acetylation is compatible with kinetochore structure and function

7 July 2018

1 reference

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BRCA1 and BRCA2: different roles in a common pathway of genome protection

7 July 2018

1 reference

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Human artificial chromosome (HAC) vector with a conditional centromere for correction of genetic deficiencies in human cells

7 July 2018

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Cancer-associated alteration of pericentromeric heterochromatin may contribute to chromosome instability

7 July 2018

1 reference

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BRCA1 tumour suppression occurs via heterochromatin-mediated silencing.

7 July 2018

1 reference

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Human artificial chromosomes for gene delivery and the development of animal models

7 July 2018

1 reference

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Functional differences among BRCA1 missense mutations in the control of centrosome duplication

7 July 2018

1 reference

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Aberrant overexpression of satellite repeats in pancreatic and other epithelial cancers

7 July 2018

1 reference

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Human artificial chromosome with a conditional centromere for gene delivery and gene expression.

7 July 2018

1 reference

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Genomic instability in breast cancer: pathogenesis and clinical implications

7 July 2018

1 reference

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BRCA1 role in the mitigation of radiotoxicity and chromosomal instability through repair of clustered DNA lesions.

7 July 2018

1 reference

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Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis

7 July 2018

1 reference

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Recent advances in lentiviral vector development and applications

7 July 2018

1 reference

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BRCA1 and its toolbox for the maintenance of genome integrity

7 July 2018

1 reference

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Integrase-defective lentiviral vectors: progress and applications.

7 July 2018

1 reference

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A transcriptomic analysis of human centromeric and pericentric sequences in normal and tumor cells

7 July 2018

1 reference

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Histone modifications within the human X centromere region

7 July 2018

1 reference

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Integration-deficient lentiviral vectors: a slow coming of age.

7 July 2018

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Lentiviral vectors with measles virus glycoproteins - dream team for gene transfer?

7 July 2018

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Advances in high-capacity extrachromosomal vector technology: episomal maintenance, vector delivery, and transgene expression.

7 July 2018

1 reference

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Inactivation of a human kinetochore by specific targeting of chromatin modifiers

7 July 2018

1 reference

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Induction and processing of complex DNA damage in human breast cancer cells MCF-7 and nonmalignant MCF-10A cells

7 July 2018

1 reference

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Evolutionary diversification of SPANX-N sperm protein gene structure and expression

7 July 2018

1 reference

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Functional characterization of a novel BRCA1-null ovarian cancer cell line in response to ionizing radiation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4245969

RNAPol-ChIP analysis of transcription from FSHD-linked tandem repeats and satellite DNA.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4245969

BRCA1 foci in normal S-phase nuclei are linked to interphase centromeres and replication of pericentric heterochromatin

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4245969

TAR cloning: insights into gene function, long-range haplotypes and genome structure and evolution

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4245969

Dynamic structure of the SPANX gene cluster mapped to the prostate cancer susceptibility locus HPCX at Xq27

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4245969

The SPANX gene family of cancer/testis-specific antigens: rapid evolution and amplification in African great apes and hominids

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4245969

Role of BRCA1 in cellular resistance to paclitaxel and ionizing radiation in an ovarian cancer cell line carrying a defective BRCA1

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4245969

Co-localization of centromere activity, proteins and topoisomerase II within a subdomain of the major human X alpha-satellite array

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4245969

Isolation of a functional copy of the human BRCA1 gene by transformation-associated recombination in yeast

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4245969

BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4245969

Genetic analysis of BRCA1 function in a defined tumor cell line

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4245969

Nucleotide sequence of the partially deleted D4Z4 locus in a patient with FSHD identifies a putative gene within each 3.3 kb element

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4245969

Structural organization of multiple alphoid subsets coexisting on human chromosomes 1, 4, 5, 7, 9, 15, 18, and 19.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4245969

Complete genomic sequence and analysis of 117 kb of human DNA containing the gene BRCA1

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4245969

Construction of mouse A9 clones containing a single human chromosome tagged with neomycin-resistance gene via microcell fusion

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4245969

Physical map of the centromeric region of human chromosome 7: relationship between two distinct alpha satellite arrays

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4245969

Microcell-mediated transfer of murine chromosomes into mouse, Chinese hamster, and human somatic cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4245969

Pig gene knockout by rAAV-mediated homologous recombination: comparison of BRCA1 gene knockout efficiency in Yucatan and Göttingen fibroblasts with slightly different target sequences.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4245969

CENP-B box and pJalpha sequence distribution in human alpha satellite higher-order repeats (HOR).

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4245969

BRCA1 and BRCA2: a common pathway of genome protection but different breast cancer subtypes

27 October 2018

1 reference

12 December 2020

Selective isolation of genomic loci from complex genomes by transformation-associated recombination cloning in the yeast Saccharomyces cerevisiae

1 reference

12 December 2020

Loss of the tumour-suppressor genes CHK2 and BRCA1 results in chromosomal instability

1 reference

12 December 2020

The disappearing Barr body in breast and ovarian cancers

1 reference

12 December 2020

Identifiers

DOI

10.1093/NAR/GKU870

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25260588%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25260588%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

PubMed publication ID

25260588

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25260588%20AND%20SRC:MED&resulttype=core&format=json