Hypocretin/orexin overexpression induces an insomnia-like phenotype in zebrafish. (Q34593415)

3 August 2017

Hypocretin/orexin overexpression induces an insomnia-like phenotype in zebrafish (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6675014&resulttype=core&format=json

11 May 2020

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2

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11 May 2020

Alexander F Schier

5

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11 May 2020

author name string

David A Prober

1

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11 May 2020

Anthony A Onah

3

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11 May 2020

Rou-Jia Sung

4

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11 May 2020

language of work or name

English

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publication date

1 December 2006

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3 August 2017

Journal of Neuroscience

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6675014&resulttype=core&format=json

11 May 2020

volume

26

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11 May 2020

issue

51

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11 May 2020

page(s)

13400-13410

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Effect of lateral cerebroventricular injection of the appetite-stimulating neuropeptide, orexin and neuropeptide Y, on the various behavioral activities of rats

11 May 2020

cites work

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12 December 2020

Hypothalamic hypocretin (orexin): robust innervation of the spinal cord

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12 December 2020

Distribution of orexin neurons in the adult rat brain

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12 December 2020

The sleep disorder canine narcolepsy is caused by a mutation in the hypocretin (orexin) receptor 2 gene

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12 December 2020

Narcolepsy in orexin knockout mice: molecular genetics of sleep regulation

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12 December 2020

Orexin A activates locus coeruleus cell firing and increases arousal in the rat.

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12 December 2020

Hypocretin (orexin) activation and synaptic innervation of the locus coeruleus noradrenergic system.

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12 December 2020

Chronic intracerebroventricular administration of orexin-A to rats increases food intake in daytime, but has no effect on body weight

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12 December 2020

Rest in Drosophila is a sleep-like state.

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12 December 2020

Correlates of sleep and waking in Drosophila melanogaster.

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12 December 2020

The novel brain neuropeptide, orexin-A, modulates the sleep-wake cycle of rats

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12 December 2020

The need for a simple animal model to understand sleep

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12 December 2020

Activity, arousal, and the MSLT in patients with insomnia.

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12 December 2020

Laser-induced gene expression in specific cells of transgenic zebrafish

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12 December 2020

Effect of lesions of the ventrolateral preoptic nucleus on NREM and REM sleep.

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12 December 2020

Orexin-induced hyperlocomotion and stereotypy are mediated by the dopaminergic system

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12 December 2020

A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains

1 reference

12 December 2020

Hypocretin-1 modulates rapid eye movement sleep through activation of locus coeruleus neurons.

1 reference

12 December 2020

Sleep and the fruit fly.

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12 December 2020

Effects of centrally administered orexin-B and orexin-A: a role for orexin-1 receptors in orexin-B-induced hyperactivity

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12 December 2020

The suprachiasmatic nucleus projects to posterior hypothalamic arousal systems.

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12 December 2020

Enhanced expression and stable transmission of transgenes flanked by inverted terminal repeats from adeno-associated virus in zebrafish

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12 December 2020

Melatonin promotes sleep-like state in zebrafish

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12 December 2020

Systemic administration of hypocretin-1 reduces cataplexy and normalizes sleep and waking durations in narcoleptic dogs

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12 December 2020

Genetic ablation of orexin neurons in mice results in narcolepsy, hypophagia, and obesity.

1 reference

12 December 2020

A neural circuit for circadian regulation of arousal.

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12 December 2020

Arousal effect of orexin A depends on activation of the histaminergic system

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12 December 2020

Orexins activate histaminergic neurons via the orexin 2 receptor

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12 December 2020

Effects of orexins on energy balance and thermoregulation.

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12 December 2020

Circadian-dependent and circadian-independent behavioral actions of hypocretin/orexin.

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12 December 2020

Entraining signals initiate behavioral circadian rhythmicity in larval zebrafish.

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12 December 2020

I-SceI meganuclease mediates highly efficient transgenesis in fish.

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12 December 2020

The role of cerebrospinal fluid hypocretin measurement in the diagnosis of narcolepsy and other hypersomnias

1 reference

12 December 2020

Perchance to dream: solving the mystery of sleep through genetic analysis

1 reference

12 December 2020

Hypothalamic orexin neurons regulate arousal according to energy balance in mice

1 reference

12 December 2020

Distinct narcolepsy syndromes in Orexin receptor-2 and Orexin null mice: molecular genetic dissection of Non-REM and REM sleep regulatory processes

1 reference

12 December 2020

Imaging neuronal activity during zebrafish behavior with a genetically encoded calcium indicator.

1 reference

12 December 2020

Critical role of dorsomedial hypothalamic nucleus in a wide range of behavioral circadian rhythms

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12 December 2020

Hypocretin (orexin): role in normal behavior and neuropathology

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12 December 2020

Effects of IV and ICV hypocretin-1 (orexin A) in hypocretin receptor-2 gene mutated narcoleptic dogs and IV hypocretin-1 replacement therapy in a hypocretin-ligand-deficient narcoleptic dog.

1 reference

12 December 2020

Of lasers, mutants, and see-through brains: functional neuroanatomy in zebrafish

1 reference

12 December 2020

The orexin/hypocretin system in zebrafish is connected to the aminergic and cholinergic systems.

1 reference

12 December 2020

Orexin peptides prevent cataplexy and improve wakefulness in an orexin neuron-ablated model of narcolepsy in mice

1 reference

12 December 2020

Behavioral state instability in orexin knock-out mice.

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12 December 2020

Lesions of the suprachiasmatic nucleus eliminate the daily rhythm of hypocretin-1 release.

1 reference

12 December 2020

Sleep homeostasis in Drosophila melanogaster.

1 reference

12 December 2020

Functional neuroimaging evidence for hyperarousal in insomnia

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12 December 2020

Convergence of circadian and sleep regulatory mechanisms on hypocretin-1.

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12 December 2020

Indirect projections from the suprachiasmatic nucleus to major arousal-promoting cell groups in rat: implications for the circadian control of behavioural state

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12 December 2020

Behavioral screening assays in zebrafish

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12 December 2020

Light-dependent development of circadian gene expression in transgenic zebrafish

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12 December 2020

In vivo drug discovery in the zebrafish

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12 December 2020

Identification of zebrafish insertional mutants with defects in visual system development and function

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12 December 2020

Reduced sleep in Drosophila Shaker mutants

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12 December 2020

Cre-mediated site-specific recombination in zebrafish embryos.

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12 December 2020

Input organization and plasticity of hypocretin neurons: possible clues to obesity's association with insomnia.

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12 December 2020

A role for lateral hypothalamic orexin neurons in reward seeking

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12 December 2020

Sleep is of the brain, by the brain and for the brain.

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12 December 2020

Clues to the functions of mammalian sleep

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12 December 2020

Insights from studying human sleep disorders

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12 December 2020

Homeostatic, circadian, and emotional regulation of sleep

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12 December 2020

Afferents to the orexin neurons of the rat brain

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12 December 2020

Orexin A in the VTA is critical for the induction of synaptic plasticity and behavioral sensitization to cocaine.

1 reference

12 December 2020

Regulation by orexin of feeding behaviour and locomotor activity in the goldfish

1 reference

12 December 2020

The neurobiology of hypocretins (orexins), narcolepsy and related therapeutic interventions

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12 December 2020

Hypocretin-1 dose-dependently modulates maternal behaviour in mice

1 reference

12 December 2020

Regulation of hypocretin (orexin) expression in embryonic zebrafish

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12 December 2020

Novel method for high-throughput phenotyping of sleep in mice.

1 reference

12 December 2020

Animal sleep: a review of sleep duration across phylogeny

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12 December 2020

A genetic screen for mutations affecting embryogenesis in zebrafish.

1 reference

12 December 2020

Genes controlling and mediating locomotion behavior of the zebrafish embryo and larva.

1 reference

12 December 2020

The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity

1 reference

12 December 2020

Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior

1 reference

12 December 2020

Neurons containing hypocretin (orexin) project to multiple neuronal systems

1 reference

12 December 2020

Orexins, orexigenic hypothalamic peptides, interact with autonomic, neuroendocrine and neuroregulatory systems

1 reference

12 December 2020

10.1523/JNEUROSCI.4332-06.2006

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6675014&resulttype=core&format=json

11 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6675014&resulttype=core&format=json

11 May 2020

1 reference