Oxysterols in biological systems: sources, metabolism and pathophysiological relevance (Q34598714)

3 August 2017

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title

Oxysterols in biological systems: sources, metabolism and pathophysiological relevance (English)

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3 August 2017

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5

Wendy Jessup

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3 August 2017

David M van Reyk

1

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ORCID Public Data File 2021

Roger Dean

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ORCID Public Data File 2021

author name string

Andrew J Brown

series ordinal

2

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PubMed ID

17207307

3 August 2017

Lillemor Mattsson Hult'en

series ordinal

3

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PubMed ID

17207307

3 August 2017

Roger T Dean

series ordinal

4

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3 August 2017

1 January 2006

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3 August 2017

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3 August 2017

11

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3 August 2017

6

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3 August 2017

255-262

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Oxysterols in human circulation: which role do they have?

3 August 2017

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https://api.crossref.org/works/10.1179%2F135100006X155003

Oxysterols: friends, foes, or just fellow passengers?

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F135100006X155003

7-Ketocholesterol delivered to mice in chylomicron remnant-like particles is rapidly metabolised, excreted and does not accumulate in aorta

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F135100006X155003

Dietary cholesterol-oxidation products accumulate in serum and liver in apolipoprotein E-deficient mice, but do not accelerate atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F135100006X155003

Effects of dietary oxysterols on coronary arteries in hyperlipidaemic hamsters

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F135100006X155003

Lymphatic transport of dietary cholesterol oxidation products, cholesterol and triacylglycerols in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F135100006X155003

Rapid hepatic metabolism of 7-ketocholesterol by 11beta-hydroxysteroid dehydrogenase type 1: species-specific differences between the rat, human, and hamster enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F135100006X155003

Oxysterol 7 alpha-hydroxylase activity by cholesterol 7 alpha-hydroxylase (CYP7A).

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F135100006X155003

Induction of 11beta-hydroxysteroid dehydrogenase type 1 but not -2 in human aortic smooth muscle cells by inflammatory stimuli

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F135100006X155003

11 Beta-hydroxysteroid dehydrogenase type 1 is induced in human monocytes upon differentiation to macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F135100006X155003

The expression of 11 beta-hydroxysteroid dehydrogenase type I by lymphocytes provides a novel means for intracrine regulation of glucocorticoid activities.

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F135100006X155003

Regulation of CYP3A genes in the human respiratory tract

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F135100006X155003

Lord of the rings--the mechanism for oxidosqualene:lanosterol cyclase becomes crystal clear

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F135100006X155003

Cholesterol autoxidation 1981-1986.

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F135100006X155003

Activation of microglial poly(ADP-ribose)-polymerase-1 by cholesterol breakdown products during neuroinflammation: a link between demyelination and neuronal damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F135100006X155003

Relevance and mechanism of oxysterol stereospecifity in coronary artery disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F135100006X155003

High circulating levels of 7beta- and 7alpha-hydroxycholesterol and presence of apoptotic and oxidative markers in arterial lesions of normocholesterolemic atherosclerotic patients undergoing endarterectomy

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F135100006X155003

Levels of 7-oxocholesterol in cerebrospinal fluid are more than one thousand times lower than reported in multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F135100006X155003

Cholesterol homeostasis in human brain: evidence for an age-dependent flux of 24S-hydroxycholesterol from the brain into the circulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F135100006X155003

Mechanism of accumulation of cholesterol and cholestanol in tendons and the role of sterol 27-hydroxylase (CYP27A1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F135100006X155003

Measurement of oxysterols and alpha-tocopherol in plasma and tissue samples as indices of oxidant stress status.

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F135100006X155003

Non-cholesterol sterols in serum, lipoproteins, and red cells in statin-treated FH subjects off and on plant stanol and sterol ester spreads

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F135100006X155003

Multifunctional roles of macrophages in the development and progression of atherosclerosis in humans and experimental animals

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F135100006X155003

Transport of side-chain oxidized oxysterols in the human circulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F135100006X155003

Effect of oxysterol-enriched low-density lipoprotein on endothelial barrier function in culture. Low-density lipoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F135100006X155003

Cytotoxicity of oxidized low-density lipoprotein in cultured RPE cells is dependent on the formation of 7-ketocholesterol

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F135100006X155003

Sterol efflux is impaired from macrophage foam cells selectively enriched with 7-ketocholesterol.

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F135100006X155003

27-hydroxycholesterol is an endogenous ligand for liver X receptor in cholesterol-loaded cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F135100006X155003

Protein sensors for membrane sterols

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F135100006X155003

The hypocholesterolemic agent LY295427 reverses suppression of sterol regulatory element-binding protein processing mediated by oxysterols

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F135100006X155003

Cholesterol and 25-hydroxycholesterol inhibit activation of SREBPs by different mechanisms, both involving SCAP and Insigs

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F135100006X155003

Cholesterol addition to ER membranes alters conformation of SCAP, the SREBP escort protein that regulates cholesterol metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F135100006X155003

The liver X receptor gene team: potential new players in atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F135100006X155003

An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F135100006X155003

Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F135100006X155003

Structural requirements of ligands for the oxysterol liver X receptors LXRalpha and LXRbeta

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F135100006X155003

Cholestenoic Acid Is a Naturally Occurring Ligand for Liver X Receptor α

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F135100006X155003

Statins inhibit synthesis of an oxysterol ligand for the liver x receptor in human macrophages with consequences for cholesterol flux

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F135100006X155003

Do oxysterols control cholesterol homeostasis?

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F135100006X155003

Oxysterols present in atherosclerotic tissue decrease the expression of lipoprotein lipase messenger RNA in human monocyte-derived macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F135100006X155003

Cholesterol Oxides Accumulate in Human Cataracts

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F135100006X155003

21 January 2018

Identifiers

DOI

10.1179/135100006X155003

1 reference

3 August 2017

1 reference

PubMed ID

17207307