Loss of LKB1 expression reduces the latency of ErbB2-mediated mammary gland tumorigenesis, promoting changes in metabolic pathways (Q34602408)

3 August 2017

Loss of LKB1 expression reduces the latency of ErbB2-mediated mammary gland tumorigenesis, promoting changes in metabolic pathways (English)

1 reference

3 August 2017

4

Paola A Marignani

1 reference

3 August 2017

2

Zhaolin Xu

1 reference

3 August 2017

Rafaela Andrade-Vieira

series ordinal

1

1 reference

PubMed ID

23451056

3 August 2017

Patricia Colp

series ordinal

3

1 reference

PubMed ID

23451056

3 August 2017

language of work or name

English

0 references

publication date

22 February 2013

1 reference

3 August 2017

1 reference

3 August 2017

8

1 reference

3 August 2017

2

1 reference

3 August 2017

e56567

1 reference

Creative Commons Attribution 4.0 International

3 August 2017

start time

22 February 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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7 July 2018

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Activation of a metabolic gene regulatory network downstream of mTOR complex 1

7 July 2018

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AZD8055 is a potent, selective, and orally bioavailable ATP-competitive mammalian target of rapamycin kinase inhibitor with in vitro and in vivo antitumor activity

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Understanding the Warburg effect: the metabolic requirements of cell proliferation

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PTEN deficiency in a luminal ErbB-2 mouse model results in dramatic acceleration of mammary tumorigenesis and metastasis

7 July 2018

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LKB1 catalytic activity contributes to estrogen receptor alpha signaling

7 July 2018

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An ATP-competitive mammalian target of rapamycin inhibitor reveals rapamycin-resistant functions of mTORC1

7 July 2018

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LKB1 signaling in mesenchymal cells required for suppression of gastrointestinal polyposis

7 July 2018

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7 July 2018

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The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin

7 July 2018

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Growing roles for the mTOR pathway

7 July 2018

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Deficiency of LKB1 in skeletal muscle prevents AMPK activation and glucose uptake during contraction

7 July 2018

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PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients.

7 July 2018

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The LKB1 tumor suppressor negatively regulates mTOR signaling

7 July 2018

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Regulation of the TSC pathway by LKB1: evidence of a molecular link between tuberous sclerosis complex and Peutz-Jeghers syndrome

7 July 2018

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The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress

7 July 2018

1 reference

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LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1

7 July 2018

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7 July 2018

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Further observations on LKB1/STK11 status and cancer risk in Peutz-Jeghers syndrome.

7 July 2018

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Activation of the tumour suppressor kinase LKB1 by the STE20-like pseudokinase STRAD

7 July 2018

1 reference

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Loss of the Lkb1 tumour suppressor provokes intestinal polyposis but resistance to transformation

7 July 2018

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7 July 2018

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7 July 2018

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neu/ERBB2 cooperates with p53-172H during mammary tumorigenesis in transgenic mice

7 July 2018

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7 July 2018

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Conditional deletion of the Lkb1 gene in the mouse mammary gland induces tumour formation.

7 July 2018

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LKB1 catalytically deficient mutants enhance cyclin D1 expression.

21 January 2018

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Towards automatic metabolomic profiling of high-resolution one-dimensional proton NMR spectra.

21 January 2018

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Dysfunctional AMPK activity, signalling through mTOR and survival in response to energetic stress in LKB1-deficient lung cancer.

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0056567

In vivo mapping of hydrogen peroxide and oxidized glutathione reveals chemical and regional specificity of redox homeostasis.

21 January 2018

1 reference

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Enhanced apoptosis and tumor growth suppression elicited by combination of MEK (selumetinib) and mTOR kinase inhibitors (AZD8055).

21 January 2018

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Alterations to either c-erbB-2(neu) or c-myc proto-oncogenes in breast carcinomas correlate with poor short-term prognosis

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23451056

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

LKB1 protein expression in human breast cancer

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23451056

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0056567

1 reference

3 August 2017

0 references

1 reference

3 August 2017

1 reference

PubMed ID

23451056