The unusual amino acid L-ergothioneine is a physiologic cytoprotectant (Q34613774)

3 August 2017

title

The unusual amino acid L-ergothioneine is a physiologic cytoprotectant (English)

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3 August 2017

1 reference

ChEBI release 2020-05-28

B D Paul

1

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3 August 2017

S H Snyder

series ordinal

2

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3 August 2017

publication date

13 November 2009

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Cell Death & Differentiation

3 August 2017

published in

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3 August 2017

volume

17

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3 August 2017

issue

7

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3 August 2017

page(s)

1134-1140

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Skin cells and tissue are capable of using L-ergothioneine as an integral component of their antioxidant defense system

3 August 2017

cites work

1 reference

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Bilirubin and glutathione have complementary antioxidant and cytoprotective roles

7 July 2018

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Dietary sources and antioxidant effects of ergothioneine

7 July 2018

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Probing the substrate specificity of the ergothioneine transporter with methimazole, hercynine, and organic cations

7 July 2018

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Decreased proliferation and erythroid differentiation of K562 cells by siRNA-induced depression of OCTN1 (SLC22A4) transporter gene.

7 July 2018

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Mechanism of the regulation of organic cation/carnitine transporter 1 (SLC22A4) by rheumatoid arthritis-associated transcriptional factor RUNX1 and inflammatory cytokines

7 July 2018

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Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases

7 July 2018

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Novel localization of OCTN1, an organic cation/carnitine transporter, to mammalian mitochondria

7 July 2018

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Functional role of the 503F variant of the organic cation transporter OCTN1 in Crohn's disease

7 July 2018

1 reference

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Discovery of the ergothioneine transporter

7 July 2018

1 reference

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Functional variants of OCTN cation transporter genes are associated with Crohn disease

7 July 2018

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Somatic mitochondrial DNA mutations in cortex and substantia nigra in aging and Parkinson's disease

7 July 2018

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An intronic SNP in a RUNX1 binding site of SLC22A4, encoding an organic cation transporter, is associated with rheumatoid arthritis

7 July 2018

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BIOSYNTHESIS OF ERGOTHIONEINE AND HERCYNINE BY MYCOBACTERIA

7 July 2018

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The biosynthesis of ergothioneine.

7 July 2018

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Electrophile and oxidant damage of mitochondrial DNA leading to rapid evolution of homoplasmic mutations

7 July 2018

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Biliverdin reductase: a major physiologic cytoprotectant

7 July 2018

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Structural and functional characteristics and tissue distribution pattern of rat OCTN1, an organic cation transporter, cloned from placenta

7 July 2018

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Protection against oxidative damage and cell death by the natural antioxidant ergothioneine

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885499

Novel membrane transporter OCTN1 mediates multispecific, bidirectional, and pH-dependent transport of organic cations

7 July 2018

1 reference

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Bilirubin, formed by activation of heme oxygenase-2, protects neurons against oxidative stress injury

7 July 2018

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Cloning and characterization of a novel human pH-dependent organic cation transporter, OCTN1

7 July 2018

1 reference

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Biosynthesis of Ergothioneine and Hercynine by Fungi and Actinomycetales

7 July 2018

1 reference

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Reactions of L-ergothioneine and some other aminothiones with2,2'-and 4,4'-dipyridyl disulphides and of L-ergothioneine with iodoacetamide. 2-Mercaptoimidazoles, 2- and 4-thiopyridones, thiourea and thioacetamide as highly reactive neutral sulphur n

7 July 2018

1 reference

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Ergothioneine as antioxidant

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885499

Fine-mapping of DNA damage and repair in specific genomic segments

7 July 2018

1 reference

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A polymerase chain reaction-based method to detect cisplatin adducts in specific genes

7 July 2018

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Expression of organic cation transporter OCTN1 in hematopoietic cells during erythroid differentiation

7 July 2018

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Increased ergothioneine tissue concentrations in carriers of the Crohn's disease risk-associated 503F variant of the organic cation transporter OCTN1.

21 January 2018

1 reference

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Ergothioneine inhibits oxidative stress- and TNF-alpha-induced NF-kappa B activation and interleukin-8 release in alveolar epithelial cells

21 January 2018

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A convenient spectrophotometric assay for the determination of L-ergothioneine in blood

21 January 2018

1 reference

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L-ergothioneine modulates oxidative damage in the kidney and liver of rats in vivo: studies upon the profile of polyunsaturated fatty acids.

21 January 2018

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Modulation of hydrogen peroxide-induced DNA damage, MAPKs activation and cell death in PC12 by ergothioneine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.163

L-Ergothioneine scavenges superoxide and singlet oxygen and suppresses TNF-alpha and MMP-1 expression in UV-irradiated human dermal fibroblasts

21 January 2018

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Identification of a mononucleotide repeat as a major target for mitochondrial DNA alterations in human tumors

26 October 2018

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Ergothioneine content in normal and senile human cataractous lenses

26 October 2018

1 reference

12 December 2020

Studies on ergothioneine. VI. Distribution and fluctuations of ergothioneine in rats

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12 December 2020

Ergothioneine distribution in bovine and porcine ocular tissues

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12 December 2020

The reaction sequence in ergothioneine biosynthesis: hercynine as an intermediate

1 reference

12 December 2020

Identifiers

DOI

10.1038/CDD.2009.163

1 reference

3 August 2017

1 reference

3 August 2017

1 reference