Therapeutics against mitochondrial oxidative stress in animal models of aging (Q34614534)

3 August 2017

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title

Therapeutics against mitochondrial oxidative stress in animal models of aging (English)

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3 August 2017

Simon Melov

1

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3 August 2017

language of work or name

English

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publication date

1 April 2002

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Annals of the New York Academy of Sciences

3 August 2017

published in

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3 August 2017

volume

959

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3 August 2017

page(s)

330-340

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Extension of Drosophila lifespan by overexpression of human SOD1 in motorneurons

3 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02104.X

Extension of life-span by overexpression of superoxide dismutase and catalase in Drosophila melanogaster.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02104.X

FLP recombinase-mediated induction of Cu/Zn-superoxide dismutase transgene expression can extend the life span of adult Drosophila melanogaster flies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02104.X

Oxidative stress, caloric restriction, and aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02104.X

Mitochondrial disease in superoxide dismutase 2 mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02104.X

A novel neurological phenotype in mice lacking mitochondrial manganese superoxide dismutase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02104.X

Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02104.X

Mice lacking extracellular superoxide dismutase are more sensitive to hyperoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02104.X

Neurodegeneration, myocardial injury, and perinatal death in mitochondrial superoxide dismutase-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02104.X

Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02104.X

Generation of superoxide anion by the NADH dehydrogenase of bovine heart mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02104.X

Dependence of H2O2 formation by rat heart mitochondria on substrate availability and donor age.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02104.X

Endogenous oxidative damage of mtDNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02104.X

Role of oxidized amino acids in protein breakdown and stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02104.X

Distribution of glutathione peroxidases and glutathione reductase in rat brain mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02104.X

Human complex I deficiency: clinical spectrum and involvement of oxygen free radicals in the pathogenicity of the defect

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02104.X

Aconitase and mitochondrial iron-sulphur protein deficiency in Friedreich ataxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02104.X

Mouse models for Friedreich ataxia exhibit cardiomyopathy, sensory nerve defect and Fe-S enzyme deficiency followed by intramitochondrial iron deposits

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02104.X

Aging: a theory based on free radical and radiation chemistry

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02104.X

Mitochondrial adenine nucleotide translocase is modified oxidatively during aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02104.X

Oxidative damage during aging targets mitochondrial aconitase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02104.X

Differential oxidative damage to mitochondrial proteins during aging.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02104.X

Protein oxidative damage is associated with life expectancy of houseflies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02104.X

Excess brain protein oxidation and enzyme dysfunction in normal aging and in Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02104.X

Free radical damage, iron, and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02104.X

Iron accumulation in Alzheimer disease is a source of redox-generated free radicals

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02104.X

Gene expression profile of aging and its retardation by caloric restriction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02104.X

Array-based gene expression profiling to study aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02104.X

Aging and resistance to oxidative damage in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02104.X

Oxidative stress and ageing in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02104.X

Mitochondrial superoxide and hydrogen peroxide generation, protein oxidative damage, and longevity in different species of flies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02104.X

Mitochondrial oxidative damage, hydrogen peroxide release, and aging.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02104.X

Relationship between antioxidants, prooxidants, and the aging process

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02104.X

Role of metabolic rate and DNA-repair in Drosophila aging: implications for the mitochondrial mutation theory of aging.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02104.X

The rate of free radical production as a determinant of the rate of aging: evidence from the comparative approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02104.X

Low mitochondrial free radical production per unit O2 consumption can explain the simultaneous presence of high longevity and high aerobic metabolic rate in birds.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02104.X

Double bond content of phospholipids and lipid peroxidation negatively correlate with maximum longevity in the heart of mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02104.X

Genetic influences on aging.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02104.X

Signals from the reproductive system regulate the lifespan of C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02104.X

Genome sequence of the nematode C. elegans: a platform for investigating biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02104.X

A C. elegans mutant that lives twice as long as wild type

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02104.X

daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02104.X

Genetic and environmental conditions that increase longevity in Caenorhabditis elegans decrease metabolic rate

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02104.X

Ambient temperature, physical activity and aging in the housefly, Musca domestica

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02104.X

A mutation in succinate dehydrogenase cytochrome b causes oxidative stress and ageing in nematodes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02104.X

Mitochondrial disease in mouse results in increased oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02104.X

Alzheimer's disease and oxidative stress: implications for novel therapeutic approaches

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02104.X

The relation between antioxidants and memory performance in the old and very old.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02104.X

Cognitive impairment and mortality in a cohort of elderly people

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02104.X

Antioxidants, metabolic rate and aging in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02104.X

Dietary antioxidants and cognitive function in a population-based sample of older persons. The Rotterdam Study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02104.X

Aconitase is a sensitive and critical target of oxygen poisoning in cultured mammalian cells and in rat lungs

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02104.X

Superoxide-driven aconitase FE-S center cycling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02104.X

Avian 3-hydroxy-3-methylglutaryl-CoA lyase: sensitivity of enzyme activity to thiol/disulfide exchange and identification of proximal reactive cysteines

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02104.X

Molecular cloning of rat mitochondrial 3-hydroxy-3-methylglutaryl-CoA lyase and detection of the corresponding mRNA and of those encoding the remaining enzymes comprising the ketogenic 3-hydroxy-3-methylglutaryl-CoA cycle in central nervous system o

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02104.X

EUK-134, a synthetic superoxide dismutase and catalase mimetic, prevents oxidative stress and attenuates kainate-induced neuropathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2002.TB02104.X

10.1111/J.1749-6632.2002.TB02104.X

21 January 2018

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DOI

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3 August 2017

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