T cells targeting carcinoembryonic antigen can mediate regression of metastatic colorectal cancer but induce severe transient colitis. (Q34621730)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21157437%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

title

T cells targeting carcinoembryonic antigen can mediate regression of metastatic colorectal cancer but induce severe transient colitis (English)

1 reference

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18 January 2020

1 reference

metastatic colon cancer

1 reference

1 reference

16

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18 January 2020

19

Steven A Rosenberg

1 reference

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18 January 2020

12

Udai S Kammula

1 reference

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18 January 2020

11

Marybeth S Hughes

1 reference

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18 January 2020

18

Carolyn M Laurencot

1 reference

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18 January 2020

6

Steven A Feldman

1 reference

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18 January 2020

author name string

Maria R Parkhurst

1

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18 January 2020

James C Yang

2

1 reference

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18 January 2020

Russell C Langan

3

1 reference

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18 January 2020

Mark E Dudley

4

1 reference

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18 January 2020

Debbie-Ann N Nathan

5

1 reference

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18 January 2020

Jeremy L Davis

7

1 reference

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18 January 2020

Richard A Morgan

8

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18 January 2020

Maria J Merino

9

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18 January 2020

Richard M Sherry

10

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18 January 2020

Giao Q Phan

13

1 reference

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18 January 2020

Ramona M Lim

14

1 reference

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18 January 2020

Stephen A Wank

15

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18 January 2020

Paul F Robbins

17

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18 January 2020

language of work or name

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14 December 2010

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18 January 2020

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18 January 2020

volume

19

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18 January 2020

issue

3

1 reference

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18 January 2020

page(s)

620-626

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Of Mice, Not Men: No Evidence for Graft-versus-Host Disease in Humans Receiving T-Cell Receptor–Transduced Autologous T Cells

18 January 2020

cites work

1 reference

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7 July 2018

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7 July 2018

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Therapy of relapsed leukemia after allogeneic hematopoietic cell transplantation with T cells specific for minor histocompatibility antigens

7 July 2018

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7 July 2018

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A herceptin-based chimeric antigen receptor with modified signaling domains leads to enhanced survival of transduced T lymphocytes and antitumor activity

7 July 2018

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Lack of specific gamma-retroviral vector long terminal repeat promoter silencing in patients receiving genetically engineered lymphocytes and activation upon lymphocyte restimulation

7 July 2018

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Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen

7 July 2018

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A phase I study of a combination of yttrium-90-labeled anti-carcinoembryonic antigen (CEA) antibody and gemcitabine in patients with CEA-producing advanced malignancies

7 July 2018

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Adoptive cell therapy for the treatment of patients with metastatic melanoma

7 July 2018

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Characterization of genetically modified T-cell receptors that recognize the CEA:691-699 peptide in the context of HLA-A2.1 on human colorectal cancer cells

7 July 2018

1 reference

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The tumor microenvironment and its role in promoting tumor growth

7 July 2018

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Adoptive cell therapy for patients with metastatic melanoma: evaluation of intensive myeloablative chemoradiation preparative regimens

7 July 2018

1 reference

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Single and dual amino acid substitutions in TCR CDRs can enhance antigen-specific T cell functions

7 July 2018

1 reference

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Toll-like receptors in tumor immunotherapy

7 July 2018

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Enhanced antitumor activity of murine-human hybrid T-cell receptor (TCR) in human lymphocytes is associated with improved pairing and TCR/CD3 stability

7 July 2018

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Cancer regression in patients after transfer of genetically engineered lymphocytes

7 July 2018

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CD8+ T-cell memory in tumor immunology and immunotherapy

7 July 2018

1 reference

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Redirection of T cells by delivering a transgenic mouse-derived MDM2 tumor antigen-specific TCR and its humanized derivative is governed by the CD8 coreceptor and affects natural human TCR expression

7 July 2018

1 reference

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Mouse models expressing human carcinoembryonic antigen (CEA) as a transgene: evaluation of CEA-based cancer vaccines

7 July 2018

1 reference

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Cutting edge: persistence of transferred lymphocyte clonotypes correlates with cancer regression in patients receiving cell transfer therapy

7 July 2018

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Immunotherapy of colorectal cancer

7 July 2018

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Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes

7 July 2018

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Circumventing tolerance to a human MDM2-derived tumor antigen by TCR gene transfer

7 July 2018

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Phase I study in advanced cancer patients of a diversified prime-and-boost vaccination protocol using recombinant vaccinia virus and recombinant nonreplicating avipox virus to elicit anti-carcinoembryonic antigen immune responses

7 July 2018

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Phase I clinical trial of a recombinant canarypoxvirus (ALVAC) vaccine expressing human carcinoembryonic antigen and the B7.1 co-stimulatory molecule

7 July 2018

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The carcinoembryonic antigen (CEA) family: structures, suggested functions and expression in normal and malignant tissues

7 July 2018

1 reference

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Lethal graft-versus-host disease in mouse models of T cell receptor gene therapy

7 July 2018

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Colorectal cancer: response to sunitinib in a heavily pretreated colorectal cancer patient

26 October 2018

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A phase I study of hyperthermic isolated hepatic perfusion with oxaliplatin in the treatment of unresectable liver metastases from colorectal cancer

26 October 2018

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Clinical and immune responses in resected colon cancer patients treated with anti-idiotype monoclonal antibody vaccine that mimics the carcinoembryonic antigen

26 October 2018

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Balancing between antitumor efficacy and autoimmune pathology in T-cell-mediated targeting of carcinoembryonic antigen

26 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21157437

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/MT.2010.272

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21157437%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21157437%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

PubMed publication ID

21157437

1 reference