Klotho inhibits transforming growth factor-beta1 (TGF-beta1) signaling and suppresses renal fibrosis and cancer metastasis in mice (Q34624546)

3 August 2017

Klotho inhibits transforming growth factor-beta1 (TGF-beta1) signaling and suppresses renal fibrosis and cancer metastasis in mice (English)

1 reference

3 August 2017

1 reference

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13

Makoto Kuro-o

1 reference

3 August 2017

4

Johanne V Pastor

1 reference

3 August 2017

Shigehiro Doi

1

1 reference

3 August 2017

Yonglong Zou

2

1 reference

3 August 2017

Osamu Togao

3

1 reference

3 August 2017

George B John

5

1 reference

3 August 2017

Lei Wang

6

1 reference

3 August 2017

Kazuhiro Shiizaki

7

1 reference

3 August 2017

Russell Gotschall

8

1 reference

3 August 2017

Susan Schiavi

9

1 reference

3 August 2017

Noriaki Yorioka

10

1 reference

3 August 2017

Masaya Takahashi

11

1 reference

3 August 2017

David A Boothman

12

1 reference

3 August 2017

language of work or name

English

0 references

publication date

5 January 2011

1 reference

Journal of Biological Chemistry

3 August 2017

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3 August 2017

286

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3 August 2017

8655-8665

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3 August 2017

10

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describes a project that uses

3 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3048747/fullTextXML

inferred from PubMed Central ID database lookup

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Klotho is a substrate for alpha-, beta- and gamma-secretase

7 July 2018

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Regulation of renal outer medullary potassium channel and renal K(+) excretion by Klotho

7 July 2018

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Removal of sialic acid involving Klotho causes cell-surface retention of TRPV5 channel via binding to galectin-1

7 July 2018

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Insulin stimulates the cleavage and release of the extracellular domain of Klotho by ADAM10 and ADAM17

7 July 2018

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Prevalence of chronic kidney disease in the United States

7 July 2018

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Pathobiology of transforming growth factor beta in cancer, fibrosis and immunologic disease, and therapeutic considerations

7 July 2018

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7 July 2018

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Tissue-specific expression of betaKlotho and fibroblast growth factor (FGF) receptor isoforms determines metabolic activity of FGF19 and FGF21

7 July 2018

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7 July 2018

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Amelioration of progressive renal injury by genetic manipulation of Klotho gene

7 July 2018

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Snail activation disrupts tissue homeostasis and induces fibrosis in the adult kidney

7 July 2018

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Klotho converts canonical FGF receptor into a specific receptor for FGF23

7 July 2018

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Regulation of fibroblast growth factor-23 signaling by klotho

7 July 2018

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The beta-glucuronidase klotho hydrolyzes and activates the TRPV5 channel

7 July 2018

1 reference

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Specificity and versatility in tgf-beta signaling through Smads

7 July 2018

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Suppression of aging in mice by the hormone Klotho

7 July 2018

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7 July 2018

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7 July 2018

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FGF-23 is a potent regulator of vitamin D metabolism and phosphate homeostasis

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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In vivo klotho gene transfer ameliorates angiotensin II-induced renal damage

7 July 2018

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Association of human aging with a functional variant of klotho

7 July 2018

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Multiple roles for activated LEF/TCF transcription complexes during hair follicle development and differentiation

7 July 2018

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Mutation of the mouse klotho gene leads to a syndrome resembling ageing

7 July 2018

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Secreted Klotho protein in sera and CSF: implication for post-translational cleavage in release of Klotho protein from cell membrane.

7 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.174037

Autosomal dominant hypophosphataemic rickets is associated with mutations in FGF23

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.174037

Therapeutic role of TGF-beta-neutralizing antibody in mouse cyclosporin A nephropathy: morphologic improvement associated with functional preservation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.174037

PPAR-gamma agonist attenuates renal interstitial fibrosis and inflammation through reduction of TGF-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.174037

Klotho reduces apoptosis in experimental ischaemic acute renal failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.174037

Severely reduced production of klotho in human chronic renal failure kidney.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.174037

Inhibition of the insulin-like growth factor receptor-1 tyrosine kinase activity as a therapeutic strategy for multiple myeloma, other hematologic malignancies, and solid tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.174037

Establishment of the anti-Klotho monoclonal antibodies and detection of Klotho protein in kidneys

21 January 2018

1 reference

12 December 2020

Measurement of cell density and necrotic fraction in human melanoma xenografts by diffusion weighted magnetic resonance imaging

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12 December 2020

Effect of combination therapy with enalapril and the TGF-beta antagonist 1D11 in unilateral ureteral obstruction

1 reference

12 December 2020

Relationship between the renal apparent diffusion coefficient and glomerular filtration rate: preliminary experience

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12 December 2020

Identifiers

DOI

10.1074/JBC.M110.174037

1 reference

release_2klxvggtxjcjzdwhuhow75hx5y

3 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/2klxvggtxjcjzdwhuhow75hx5y

24 November 2022

mapped directly with Wikidata item

PMCID

3048747

1 reference

3 August 2017

1 reference